| MeSH term | MeSH ID | Detail |
|---|---|---|
| Airway Obstruction | D000402 | 13 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
Ltd4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ltd4?
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ltd4
PubChem Associated disorders and diseases
What pathways are associated with Ltd4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ltd4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ltd4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ltd4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ltd4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ltd4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Ltd4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Campos MR et al. | Differential kinase requirement for enhancement of Fc gammaR-mediated phagocytosis in alveolar macrophages by leukotriene B4 vs. D4. | 2009 | Mol. Immunol. | pmid:19223078 |
| Lee TH et al. | Leukotriene E4: perspective on the forgotten mediator. | 2009 | J. Allergy Clin. Immunol. | pmid:19482346 |
| Austen KF et al. | The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications. | 2009 | J. Allergy Clin. Immunol. | pmid:19647860 |
| Theron AJ et al. | Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants. | 2009 | Inflamm. Res. | pmid:19184354 |
| Farias S et al. | Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury. | 2009 | J. Neurotrauma | pmid:19886806 |
| Hashimoto K et al. | Cysteinyl leukotrienes induce monocyte chemoattractant protein-1 in human monocyte/macrophages via mitogen-activated protein kinase and nuclear factor-kappaB pathways. | 2009 | Int. Arch. Allergy Immunol. | pmid:19218821 |
| Muraki M et al. | Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication. | 2009 | Int. Immunopharmacol. | pmid:19706339 |
| Mizutani N et al. | Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis. | 2009 | Eur. J. Pharmacol. | pmid:19022242 |
| Fang SH et al. | Pranlukast attenuates ischemia-like injury in endothelial cells via inhibiting reactive oxygen species production and nuclear factor-kappaB activation. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19129732 |
| Claesson HE | On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19130894 |
| Boehmler AM et al. | The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells. | 2009 | J. Immunol. | pmid:19454674 |
| Mori M et al. | Eosinophil superoxide anion generation induced by adhesion molecules and leukotriene D4. | 2009 | Int. Arch. Allergy Immunol. | pmid:19494502 |
| Yang HS et al. | [Effects of leukotriene receptor antagonists on vascular endothelial growth factor and its receptors in a sensitized rat model]. | 2009 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:19575935 |
| Maekawa A et al. | GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19561298 |
| Pugliese AM et al. | Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:19625605 |
| Hori M et al. | NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. | 2009 | Eur. J. Pharmacol. | pmid:19616537 |
| Mezhybovska M et al. | Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells. | 2009 | Br. J. Cancer | pmid:19826421 |
| Thivierge M et al. | Cysteinyl-leukotriene receptor type 1 expression and function is down-regulated during monocyte-derived dendritic cell maturation with zymosan: involvement of IL-10 and prostaglandins. | 2009 | J. Immunol. | pmid:19846883 |
| Schäper C et al. | Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis. | 2009 | J Investig Allergol Clin Immunol | pmid:20128420 |
| Selg E et al. | Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19103301 |