15-epi-lxa4;15r-lxa4

15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-epi-lxa4;15r-lxa4?

15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4

PubChem Associated disorders and diseases

What pathways are associated with 15-epi-lxa4;15r-lxa4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-epi-lxa4;15r-lxa4?

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What functions are associated with 15-epi-lxa4;15r-lxa4?


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What lipids are associated with 15-epi-lxa4;15r-lxa4?

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What genes are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

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NCBI Entrez Crosslinks

All references with 15-epi-lxa4;15r-lxa4

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Authors Title Published Journal PubMed Link
Higgins G et al. Physiological impact of abnormal lipoxin Aâ‚„ production on cystic fibrosis airway epithelium and therapeutic potential. 2015 Biomed Res Int pmid:25866809
Kong X et al. Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin. 2015 Mol Med Rep pmid:25760938
Barnig C and Levy BD Innate immunity is a key factor for the resolution of inflammation in asthma. 2015 Eur Respir Rev pmid:25726564
Souza MC et al. Lipoxin A4 attenuates endothelial dysfunction during experimental cerebral malaria. 2015 Int. Immunopharmacol. pmid:25576659
Rinaldi SF et al. 15-epi-lipoxin A4 reduces the mortality of prematurely born pups in a mouse model of infection-induced preterm birth. 2015 Mol. Hum. Reprod. pmid:25567326
Petri MH et al. Aspirin-triggered 15-epi-lipoxin Aâ‚„ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation. 2015 Int. J. Cardiol. pmid:25464488
Karra L et al. Lipoxin Bâ‚„ promotes the resolution of allergic inflammation in the upper and lower airways of mice. 2015 Mucosal Immunol pmid:25465102
Wang X et al. Resolution of inflammation is altered in Alzheimer's disease. 2015 Alzheimers Dement pmid:24530025
Tateishi N et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. 2015 Lipids Health Dis pmid:25595700
Fahel JS et al. 5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. 2015 Infect. Immun. pmid:25583526