15-epi-lxa4;15r-lxa4

15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-epi-lxa4;15r-lxa4?

15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Lung Diseases D008171 37 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Edema D004487 152 associated lipids
Osteitis D010000 10 associated lipids
Asthma D001249 52 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Peritonitis D010538 38 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperplasia D006965 34 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Nasal Polyps D009298 26 associated lipids
Hyperalgesia D006930 42 associated lipids
Toxoplasmosis D014123 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-epi-lxa4;15r-lxa4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-epi-lxa4;15r-lxa4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-epi-lxa4;15r-lxa4?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 15-epi-lxa4;15r-lxa4

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Per page 10 20 50 100 | Total 602
Authors Title Published Journal PubMed Link
Zong L et al. Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer. 2016 Oxid Med Cell Longev pmid:26649143
Pedruzzi G et al. Understanding PGE2, LXA4 and LTB4 balance during Mycobacterium tuberculosis infection through mathematical model. 2016 J. Theor. Biol. pmid:26551160
Diaz-Gerevini GT et al. Beneficial action of resveratrol: How and why? 2016 Nutrition pmid:26706021
Wu B et al. Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. 2016 FASEB J. pmid:26965685
Das UN Inflammatory bowel disease as a disorder of an imbalance between pro- and anti-inflammatory molecules and deficiency of resolution bioactive lipids. 2016 Lipids Health Dis pmid:26762544
Guo Z et al. Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats. 2016 Stroke pmid:26732571
Li L et al. New development in studies of formyl-peptide receptors: critical roles in host defense. 2016 J. Leukoc. Biol. pmid:26701131
DoÄŸan B et al. Lipoxin A4 and Neutrophil/Lymphocyte Ratio: A Possible Indicator in Achieved Systemic Risk Factors for Periodontitis. 2015 Med. Sci. Monit. pmid:26298769
Lehmann C et al. Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein. 2015 FASEB J. pmid:26289316
Dunn HC et al. Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model. 2015 J. Alzheimers Dis. pmid:25125468