15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.
To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
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Authors | Title | Published | Journal | PubMed Link |
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Elias I et al. | ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. | 2016 | Diabetes | pmid:27207555 |
Han X et al. | Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner. | 2016 | Oxid Med Cell Longev | pmid:27375835 |
Brigatte P et al. | Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin Aâ‚„. | 2016 | Mediators Inflamm. | pmid:27190493 |
Higgins G et al. | Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27084849 |
Wang CS et al. | ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland. | 2016 | Sci Rep | pmid:27064029 |
Martini AC et al. | Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection. | 2016 | J Neuroinflammation | pmid:27059991 |
Tahan F et al. | Increased Postexercise Lipoxin A4 Levels in Exhaled Breath Condensate in Asthmatic Children With Exercise-Induced Bronchoconstriction. | 2016 | J Investig Allergol Clin Immunol | pmid:27012012 |
Wu B et al. | Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. | 2016 | FASEB J. | pmid:26965685 |
Das UN | Inflammatory bowel disease as a disorder of an imbalance between pro- and anti-inflammatory molecules and deficiency of resolution bioactive lipids. | 2016 | Lipids Health Dis | pmid:26762544 |
Guo Z et al. | Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats. | 2016 | Stroke | pmid:26732571 |