15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.
To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
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Authors | Title | Published | Journal | PubMed Link |
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Yu D et al. | Inverse Relationship between Serum Lipoxin A4 Level and the Risk of Metabolic Syndrome in a Middle-Aged Chinese Population. | 2015 | PLoS ONE | pmid:26565966 |
Dakin SG et al. | Inflammation activation and resolution in human tendon disease. | 2015 | Sci Transl Med | pmid:26511510 |
Rinaldi SF et al. | 15-epi-lipoxin A4 reduces the mortality of prematurely born pups in a mouse model of infection-induced preterm birth. | 2015 | Mol. Hum. Reprod. | pmid:25567326 |
Petri MH et al. | Aspirin-triggered 15-epi-lipoxin Aâ‚„ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation. | 2015 | Int. J. Cardiol. | pmid:25464488 |
Alvarez AM et al. | Aspirin-triggered lipoxin prevents antiphospholipid antibody effects on human trophoblast migration and endothelial cell interactions. | 2015 | pmid:25370166 | |
Gobbetti T et al. | Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor. | 2015 | Br. J. Pharmacol. | pmid:25296998 |
Karra L et al. | Lipoxin Bâ‚„ promotes the resolution of allergic inflammation in the upper and lower airways of mice. | 2015 | Mucosal Immunol | pmid:25465102 |
Lee JY et al. | Immune parameters differentiating active from latent tuberculosis infection in humans. | 2015 | Tuberculosis (Edinb) | pmid:26520601 |
Homann J et al. | In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse. | 2015 | PLoS ONE | pmid:26599340 |
Ribeiro LR et al. | Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis. | 2015 | Mediators Inflamm. | pmid:26635449 |