15-epi-lxa4;15r-lxa4

15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-epi-lxa4;15r-lxa4?

15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Peritonitis D010538 38 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperplasia D006965 34 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Nasal Polyps D009298 26 associated lipids
Hyperalgesia D006930 42 associated lipids
Toxoplasmosis D014123 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-epi-lxa4;15r-lxa4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-epi-lxa4;15r-lxa4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 15-epi-lxa4;15r-lxa4

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Per page 10 20 50 100 | Total 602
Authors Title Published Journal PubMed Link
Colby JK et al. Lipoxin Signaling in Murine Lung Host Responses to Cryptococcus neoformans Infection. 2016 Am. J. Respir. Cell Mol. Biol. pmid:26039320
Pedruzzi G et al. Understanding PGE2, LXA4 and LTB4 balance during Mycobacterium tuberculosis infection through mathematical model. 2016 J. Theor. Biol. pmid:26551160
Elias I et al. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. 2016 Diabetes pmid:27207555
Pazdrak K et al. Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling. 2016 J. Immunol. pmid:27742828
Chandrasekharan JA et al. Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis. 2016 J. Virol. pmid:27681120
Han X et al. Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner. 2016 Oxid Med Cell Longev pmid:27375835
Brigatte P et al. Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin Aâ‚„. 2016 Mediators Inflamm. pmid:27190493
Higgins G et al. Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa. 2016 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27084849
Wang CS et al. ALX/FPR2 Modulates Anti-Inflammatory Responses in Mouse Submandibular Gland. 2016 Sci Rep pmid:27064029
Martini AC et al. Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection. 2016 J Neuroinflammation pmid:27059991