| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Osteitis | D010000 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
15-epi-lxa4;15r-lxa4
15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-epi-lxa4;15r-lxa4?
15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4
PubChem Associated disorders and diseases
What pathways are associated with 15-epi-lxa4;15r-lxa4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-epi-lxa4;15r-lxa4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?
Knock-out
Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 15-epi-lxa4;15r-lxa4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kikuta Y et al. | Purification and characterization of recombinant rat hepatic CYP4F1. | 1999 | Arch. Biochem. Biophys. | pmid:10486137 |
| Titos E et al. | Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). | 1999 | Am. J. Physiol. | pmid:10564079 |
| Filep JG et al. | Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions. | 1999 | Blood | pmid:10590058 |
| Bandeira-Melo C et al. | Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia. | 2000 | J. Immunol. | pmid:10623853 |
| Godson C et al. | Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. | 2000 | J. Immunol. | pmid:10657608 |
| Bandeira-Melo C et al. | Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. | 2000 | J. Immunol. | pmid:10679058 |
| Sodin-Semrl S et al. | Lipoxin A4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases. | 2000 | J. Immunol. | pmid:10679106 |
| Pouliot M and Serhan CN | Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-alpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis relevant to periodontal diseases. | 1999 | J. Periodont. Res. | pmid:10685363 |
| Desplat V et al. | Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines. | 1999 | Mediators Inflamm. | pmid:10704149 |
| Chiang N et al. | Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation. | 2000 | J. Exp. Med. | pmid:10748237 |