| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Osteitis | D010000 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
15-epi-lxa4;15r-lxa4
15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-epi-lxa4;15r-lxa4?
15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4
PubChem Associated disorders and diseases
What pathways are associated with 15-epi-lxa4;15r-lxa4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-epi-lxa4;15r-lxa4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?
Knock-out
Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 15-epi-lxa4;15r-lxa4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Qiu FH et al. | Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils. | 2001 | FASEB J. | pmid:11687510 |
| Goulet JL et al. | Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice. | 2001 | J. Immunol. | pmid:11714834 |
| Aliberti J et al. | Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. | 2002 | Nat. Immunol. | pmid:11743584 |
| Vachier I et al. | Endogenous anti-inflammatory mediators from arachidonate in human neutrophils. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779156 |
| Fierro IM et al. | Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4). | 2002 | J. Pharmacol. Exp. Ther. | pmid:11805195 |
| Resnati M et al. | The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11818541 |
| Gewirtz AT et al. | Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. | 2002 | J. Immunol. | pmid:11994483 |
| Aliberti J and Sher A | Positive and negative regulation of pathogen induced dendritic cell function by G-protein coupled receptors. | 2002 | Mol. Immunol. | pmid:12009566 |
| Bonnans C et al. | Lipoxins are potential endogenous antiinflammatory mediators in asthma. | 2002 | Am. J. Respir. Crit. Care Med. | pmid:12045128 |
| Maderna P et al. | Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases. | 2002 | Am. J. Pathol. | pmid:12057930 |