| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
Total
1
15-hpete
15-hpete is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 15-hpete
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-hpete
NCBI Entrez Crosslinks
All references with 15-hpete
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Piomelli D | The ligand that came from within. | 2001 | Trends Pharmacol. Sci. | pmid:11165666 |
| Yoshinaga M et al. | 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165036 |
| Kalyankrishna S et al. | Arachidonic acid-derived oxidation products initiate apoptosis in vascular smooth muscle cells. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428675 |
| Hung ND et al. | Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19819343 |
| Van Diest MJ et al. | Influence of hypercholesterolaemia on the reactivity of isolated rabbit arteries to 15-lipoxygenase metabolites of arachidonic acid: comparison with platelet-derived agents and vasodilators. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8848433 |
| Rock C and Moos PJ | Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. | 2010 Oct-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20826080 |
| Sakai K et al. | 12-Hydroperoxyeicosatetraenoic acid (12-HPETE) and 15-HPETE stimulate melatonin synthesis in rat pineals. | 1988 | Prostaglandins | pmid:3187058 |
| Trachte GJ et al. | Potent constriction of cat coronary arteries by hydroperoxides of arachidonic acid and its blockade by anti-inflammatory agents. | 1979 | Prostaglandins | pmid:547310 |
| Van Diest MJ et al. | Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels. | 1986 | Prostaglandins | pmid:3094100 |
| Goetzl EJ et al. | Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid. | 1980 | Prostaglandins | pmid:6247746 |
| Kühn H | Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)XY-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)XY-9Z,11E-octadecadienoic acid. | 1996 | Prog. Lipid Res. | pmid:9082450 |
| Maas RL and Brash AR | Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes. | 1983 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6304687 |
| Capdevila J et al. | Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6801662 |
| Hwang SW et al. | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10823958 |
| Serhan CN et al. | On the stereochemistry and biosynthesis of lipoxin B. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3083410 |
| Tang DG et al. | Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8643560 |
| Vijil C et al. | Arachidonate 15-lipoxygenase enzyme products increase platelet aggregation and thrombin generation. | 2014 | PLoS ONE | pmid:24533104 |
| Suzuki Y et al. | Gamma-aminobutyric acid-induced contraction of the dog basilar artery. | 1984 | Pharmacology | pmid:6463098 |
| d'Ischia M et al. | Interactions of nitric oxide with lipid peroxidation products under aerobic conditions: inhibitory effects on the formation of malondialdehyde and related thiobarbituric acid-reactive substances. | 2000 | Nitric Oxide | pmid:10733868 |
| Kobayashi M et al. | [Effects of 15-hydroperoxy arachidonic acid and non-purified hydroperoxides from arachidonic acid to rabbit blood vessels (author's transl)]. | 1980 | Nihon Ronen Igakkai Zasshi | pmid:7373935 |
| Rabier M et al. | 15-Lipoxygenase products stimulate prolactin secretion from a cloned strain of rat pituitary cells. | 1988 | Neuroendocrinology | pmid:3131692 |
| Bizzozero OA et al. | Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion. | 2007 | Neurochem. Res. | pmid:17551832 |
| Marnett LJ et al. | Mechanism of the stimulation of prostaglandin H synthase and prostacyclin synthase by the antithrombotic and antimetastatic agent, nafazatrom. | 1984 | Mol. Pharmacol. | pmid:6434940 |
| Chansel D et al. | Modulation of renin synthesis by lipoxygenase products in cultured human mesangial cells. | 1989 | Mol. Cell. Endocrinol. | pmid:2545491 |
| McCarty M | Can dietary selenium reduce leukotriene production? | 1984 | Med. Hypotheses | pmid:6323934 |
| Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
| Takahashi M et al. | Vascular effects of 15-hydroperoxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid on canine arteries. | 1985 | Jpn. J. Pharmacol. | pmid:3925206 |
| Uotila P et al. | Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta. | 1987 | J. Pharmacol. Exp. Ther. | pmid:3116200 |
| Koide T et al. | Possible mechanisms of 15-hydroperoxyarachidonic acid-induced contraction of the canine basilar artery in vitro. | 1982 | J. Pharmacol. Exp. Ther. | pmid:6804622 |
| Matsuda H et al. | Pharmacodynamics of 15(S)-hydroperoxyeicosatetraenoic (15-HPETE) and 15(S)-hydroxyeicosatetraenoic acid (15-HETE) in isolated arteries from guinea pig, rabbit, rat and human. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791089 |
| Van Diest MJ et al. | 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1824864 |
| Shimizu T et al. | Activation of the arachidonate 5-lipoxygenase pathway in the canine basilar artery after experimental subarachnoidal hemorrhage. | 1988 | J. Neurochem. | pmid:2843605 |
| Mochizuki-Oda N et al. | Arachidonic acid activates cation channels in bovine adrenal chromaffin cells. | 1993 | J. Neurochem. | pmid:7693870 |
| Koide T et al. | Alterations of the eicosanoid synthetic capacity of rat brain microvessels following ischemia: relevance to ischemic brain edema. | 1985 | J. Neurochem. | pmid:3964837 |
| Furukawa K et al. | The restorative action of coenzyme Q10 in 2,4-dinitrophenol-depressed electrical and contractile activities of guinea-pig heart. | 1983 | J. Mol. Cell. Cardiol. | pmid:6355490 |
| Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1. | 2000 | J. Lipid Res. | pmid:10974056 |
| Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3. | 2000 | J. Lipid Res. | pmid:10974057 |
| Gualde N et al. | Induction of suppressor cells from peripheral blood T cells by 15-hydroperoxyeicosatetraenoic acid (15-HPETE). | 1985 | J. Immunol. | pmid:2931484 |
| Balboa MA et al. | Amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A2 is regulated by cytosolic phospholipase A2-derived hydroperoxyeicosatetraenoic acid. | 2003 | J. Immunol. | pmid:12847271 |
| Ferrante JV and Ferrante A | Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line. | 2005 | J. Immunol. | pmid:15749845 |
| Moghaddami N et al. | Unique effect of arachidonic acid on human neutrophil TNF receptor expression: up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A2. | 2003 | J. Immunol. | pmid:12928414 |
| Gualde N et al. | Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets. | 1985 | J. Immunol. | pmid:2981258 |
| Patrono C and Pugliese F | The involvement of arachidonic acid metabolism in the control of renin release. | 1980 Apr-Jun | J. Endocrinol. Invest. | pmid:6993550 |
| Naccache PH et al. | Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils. | 1981 | J. Clin. Invest. | pmid:6262382 |
| Kent RS et al. | Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta. | 1983 | J. Clin. Invest. | pmid:6409932 |
| Ferrante JV et al. | Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production. | 1997 | J. Clin. Invest. | pmid:9077554 |
| Maccarrone M et al. | Lipoxygenase products induce ultraweak light emission from human erythroleukemia cells. | 1997 Nov-Dec | J. Biolumin. Chemilumin. | pmid:9509336 |
| Brash AR et al. | Investigation of the selectivity of hydrogen abstraction in the nonenzymatic formation of hydroxyeicosatetraenoic acids and leukotrienes by autoxidation. | 1985 | J. Biol. Chem. | pmid:2984196 |
| Maas RL et al. | Investigation of the chemical conversion of hydroperoxyeicosatetraenoate to leukotriene epoxide using stereospecifically labeled arachidonic acid. Comparison with the enzymatic reaction. | 1985 | J. Biol. Chem. | pmid:2984197 |
| Landino LM et al. | Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation. | 1997 | J. Biol. Chem. | pmid:9261177 |