15-hpete

15-hpete is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 15-hpete

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-hpete

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Total 1

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All references with 15-hpete

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Authors Title Published Journal PubMed Link
Humes JL et al. Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids. 1986 Biochem. J. pmid:3082323
Uotila P et al. Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta. 1987 J. Pharmacol. Exp. Ther. pmid:3116200
Hecker M et al. Preparative HPLC purification of prostaglandin endoperoxides and isolation of novel cyclooxygenase-derived arachidonic acid metabolites. 1987 Biochem. Pharmacol. pmid:3105538
Gut J et al. Quantification of 5- and 15-HPETE's by direct chemical ionization mass spectrometry. 1987 Free Radic. Biol. Med. pmid:3319797
Markey CM et al. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. 1987 J. Biol. Chem. pmid:3106353
Kulmacz RJ et al. Heme spin states and peroxide-induced radical species in prostaglandin H synthase. 1987 J. Biol. Chem. pmid:3038886
Antonipillai I et al. The inhibitory role of 12- and 15-lipoxygenase products on renin release. 1987 Hypertension pmid:3298043
Weiss RH et al. Transformation of an arachidonic acid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450. 1987 Arch. Biochem. Biophys. pmid:3813540
Dahlén SE et al. Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. 1987 Acta Physiol. Scand. pmid:3630737
Gryglewski RJ et al. On the mechanism of antithrombotic action of flavonoids. 1987 Biochem. Pharmacol. pmid:3101704
Sakai K et al. 12-Hydroperoxyeicosatetraenoic acid (12-HPETE) and 15-HPETE stimulate melatonin synthesis in rat pineals. 1988 Prostaglandins pmid:3187058
Ueda N and Yamamoto S The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes. 1988 J. Biol. Chem. pmid:3338999
Vedelago HR and Mahadevappa VG Differential effects of 15-HPETE on arachidonic acid metabolism in collagen-stimulated human platelets. 1988 Biochem. Biophys. Res. Commun. pmid:3122753
Shimizu T et al. Activation of the arachidonate 5-lipoxygenase pathway in the canine basilar artery after experimental subarachnoidal hemorrhage. 1988 J. Neurochem. pmid:2843605
Rabier M et al. 15-Lipoxygenase products stimulate prolactin secretion from a cloned strain of rat pituitary cells. 1988 Neuroendocrinology pmid:3131692
Cashman JR et al. Inhibition of human leukocyte 5-lipoxygenase by 15-HPETE and related eicosanoids. 1988 Biochem. Biophys. Res. Commun. pmid:3415693
Marshall PJ and Kulmacz RJ Prostaglandin H synthase: distinct binding sites for cyclooxygenase and peroxidase substrates. 1988 Arch. Biochem. Biophys. pmid:3140729
Goodwin JS and Behrens T Role of lipoxygenase metabolites of arachidonic acid in T cell activation. 1988 Ann. N. Y. Acad. Sci. pmid:2837956
Vanderhoek JY Role of the 15-lipoxygenase in the immune system. 1988 Ann. N. Y. Acad. Sci. pmid:3132881
Reynolds CH Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. 1988 Biochem. Pharmacol. pmid:3144281
Fruteau de Laclos B and Borgeat P Conditions for the formation of the oxo derivatives of arachidonic acid from platelet 12-lipoxygenase and soybean 15-lipoxygenase. 1988 Biochim. Biophys. Acta pmid:3124882
Bordet JC et al. Hydroperoxides produced by n-6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds. 1988 Biochim. Biophys. Acta pmid:3124885
Kim MR et al. Inactivation of potato lipoxygenase by hydroperoxy acids as suicide substrates. 1989 Biochem. Biophys. Res. Commun. pmid:2511843
McColl SR et al. Activation of the human neutrophil 5-lipoxygenase by exogenous arachidonic acid: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins. 1989 Br. J. Pharmacol. pmid:2507084
Smith CV and Reilly MH Formation of pentane versus 1-pentanol in the ferrous sulfate-initiated decomposition of 15-hydroperoxyeicosatetraenoic acid in hypoxic and hyperoxic conditions. 1989 Biochem. Pharmacol. pmid:2706024
Garrick R et al. Transformation of leukotriene A4 to lipoxins by rat kidney mesangial cell. 1989 Biochem. Biophys. Res. Commun. pmid:2547366
Pace-Asciak CR and Asotra S Biosynthesis, catabolism, and biological properties of HPETEs, hydroperoxide derivatives of arachidonic acid. 1989 Free Radic. Biol. Med. pmid:2514125
Ng CF et al. Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1). 1989 Biochim. Biophys. Acta pmid:2503031
Wang J et al. Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid. 1989 FEBS Lett. pmid:2494061
Najid A et al. Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture. 1989 Cancer Lett. pmid:2502308
Raza H et al. Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. 1989 Biochem. Biophys. Res. Commun. pmid:2500117
Chansel D et al. Modulation of renin synthesis by lipoxygenase products in cultured human mesangial cells. 1989 Mol. Cell. Endocrinol. pmid:2545491
Murota S et al. The control of vascular endothelial cell injury. 1990 Ann. N. Y. Acad. Sci. pmid:2248437
Weitberg AB Hydroxy- and hydroperoxy-6,8,11,14-eicosatetraenoic acids induce sister chromatid exchanges in cultured mammalian cells. 1990 Am. J. Med. Sci. pmid:2105055
Andrianarison RH et al. Positional specificity of a Lupinus albus lipoxygenase in relation to enzyme concentration and effect of a double dioxygenation product of arachidonic acid. 1990 Biochem. Biophys. Res. Commun. pmid:2123103
Iwahashi H et al. Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s. 1991 Biochem. J. pmid:1646600
Force T et al. Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. 1991 J. Biol. Chem. pmid:1900289
Van Diest MJ et al. 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. 1991 J. Pharmacol. Exp. Ther. pmid:1824864
Uski TK and Högestätt ED Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries. 1992 Gen. Pharmacol. pmid:1592217
Hosni M et al. Diethyldithiocarbamate (ditiocarb sodium) effect on arachidonic acid metabolism in human mononuclear cells. Glutathione peroxidase-like activity. 1992 Biochem. Pharmacol. pmid:1314059
Henrich WL et al. Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE. 1992 Am. J. Physiol. pmid:1415738
McDonald PP et al. Activation of the human neutrophil 5-lipoxygenase by leukotriene B4. 1992 Br. J. Pharmacol. pmid:1330161
Mack SR et al. The human sperm acrosome reaction does not depend on arachidonic acid metabolism via the cyclooxygenase and lipoxygenase pathways. 1992 Nov-Dec J. Androl. pmid:1338069
Tebbey PW and Buttke TM Independent arachidonic acid-mediated gene regulatory pathways in lymphocytes. 1993 Biochem. Biophys. Res. Commun. pmid:8102055
Calzada C and Rice-Evans C Ruptured erythrocytes inhibit the oxidation of membranes by 15-hydroperoxy-eicosatetraenoic acid. 1993 FEBS Lett. pmid:8354383
Mochizuki-Oda N et al. Arachidonic acid activates cation channels in bovine adrenal chromaffin cells. 1993 J. Neurochem. pmid:7693870
Kühn H et al. Overexpression, purification and characterization of human recombinant 15-lipoxygenase. 1993 Biochim. Biophys. Acta pmid:8334154
Van Diest MJ et al. Vascular interaction between 5-hydroxytryptamine and 15-lipoxygenase metabolites of arachidonic acid. 1993 Eur. J. Pharmacol. pmid:8453981
Kiran Kumar YV et al. Differential effects of 15-HPETE and 15-HETE on BHK-21 cell proliferation and macromolecular composition. 1993 Biochim. Biophys. Acta pmid:8384883
MacMillan DK et al. Eosinophil 15-lipoxygenase is a leukotriene A4 synthase. 1994 J. Biol. Chem. pmid:7929400