MeSH term | MeSH ID | Detail |
---|---|---|
Hypertension | D006973 | 115 associated lipids |
Total
1
15-hpete is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with 15-hpete
MeSH term | MeSH ID | Detail |
---|---|---|
Hypertension | D006973 | 115 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Wu G et al. | A mechanistic study of self-inactivation of the peroxidase activity in prostaglandin H synthase-1. | 1999 | J. Biol. Chem. | pmid:10092596 |
Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
Cao YZ et al. | Altered eicosanoid biosynthesis in selenium-deficient endothelial cells. | 2000 | Free Radic. Biol. Med. | pmid:10699749 |
d'Ischia M et al. | Interactions of nitric oxide with lipid peroxidation products under aerobic conditions: inhibitory effects on the formation of malondialdehyde and related thiobarbituric acid-reactive substances. | 2000 | Nitric Oxide | pmid:10733868 |
Whalen MM et al. | Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. | 1999 | Cell. Physiol. Biochem. | pmid:10749996 |
Hwang SW et al. | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10823958 |
Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1. | 2000 | J. Lipid Res. | pmid:10974056 |
Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3. | 2000 | J. Lipid Res. | pmid:10974057 |
O'Donnell VB et al. | Catalytic consumption of nitric oxide by prostaglandin H synthase-1 regulates platelet function. | 2000 | J. Biol. Chem. | pmid:10993875 |
Piomelli D | The ligand that came from within. | 2001 | Trends Pharmacol. Sci. | pmid:11165666 |
pmid:11165876 | ||||
Prabhu KS et al. | Microsomal glutathione S-transferase A1-1 with glutathione peroxidase activity from sheep liver: molecular cloning, expression and characterization. | 2001 | Biochem. J. | pmid:11716762 |
Yin H et al. | Formation of isoprostane bicyclic endoperoxides from the autoxidation of cholesteryl arachidonate. | 2002 | J. Am. Chem. Soc. | pmid:12083928 |
Kalyankrishna S et al. | Arachidonic acid-derived oxidation products initiate apoptosis in vascular smooth muscle cells. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428675 |
Baker LM and Poole LB | Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. | 2003 | J. Biol. Chem. | pmid:12514184 |
pmid:12543246 | ||||
Manini P et al. | Ni2+ enhances Fe2+/peroxide-induced oxidation of arachidonic acid and formation of geno/cytotoxic 4-hydroxynonenal: a possible contributory mechanism in nickel toxicity and allergenicity. | 2003 | Biochim. Biophys. Acta | pmid:12667605 |
Balboa MA et al. | Amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A2 is regulated by cytosolic phospholipase A2-derived hydroperoxyeicosatetraenoic acid. | 2003 | J. Immunol. | pmid:12847271 |
Moghaddami N et al. | Unique effect of arachidonic acid on human neutrophil TNF receptor expression: up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A2. | 2003 | J. Immunol. | pmid:12928414 |
Hosni M et al. | Diethyldithiocarbamate (ditiocarb sodium) effect on arachidonic acid metabolism in human mononuclear cells. Glutathione peroxidase-like activity. | 1992 | Biochem. Pharmacol. | pmid:1314059 |
pmid:1314541 | ||||
McDonald PP et al. | Activation of the human neutrophil 5-lipoxygenase by leukotriene B4. | 1992 | Br. J. Pharmacol. | pmid:1330161 |
Mack SR et al. | The human sperm acrosome reaction does not depend on arachidonic acid metabolism via the cyclooxygenase and lipoxygenase pathways. | 1992 Nov-Dec | J. Androl. | pmid:1338069 |
Henrich WL et al. | Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE. | 1992 | Am. J. Physiol. | pmid:1415738 |
pmid:14622984 | ||||
Cavalieri B et al. | Ischaemic preconditioning modulates the activity of Kupffer cells during in vivo reperfusion injury of rat liver. | 2003 | Cell Biochem. Funct. | pmid:14624466 |
Trang T et al. | Involvement of spinal lipoxygenase metabolites in hyperalgesia and opioid tolerance. | 2004 | Eur. J. Pharmacol. | pmid:15102529 |
Yu MK et al. | Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes. | 2004 | J. Biol. Chem. | pmid:15123685 |
Yoshinaga M et al. | 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165036 |
pmid:1520701 | ||||
pmid:1523215 | ||||
Clark SR et al. | Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. | 2005 | Biochem. J. | pmid:15461587 |
Ruddat VC et al. | Tryptophan 500 and arginine 707 define product and substrate active site binding in soybean lipoxygenase-1. | 2004 | Biochemistry | pmid:15476400 |
pmid:15650406 | ||||
pmid:15723435 | ||||
Ferrante JV and Ferrante A | Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line. | 2005 | J. Immunol. | pmid:15749845 |
Uski TK and Högestätt ED | Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries. | 1992 | Gen. Pharmacol. | pmid:1592217 |
pmid:15967159 | ||||
Coffa G et al. | On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant. | 2005 | J. Biol. Chem. | pmid:16157595 |
Trigona WL et al. | Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells. | 2006 | Biochem. J. | pmid:16209660 |
Iwahashi H et al. | Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s. | 1991 | Biochem. J. | pmid:1646600 |
Wu G et al. | Oxyferryl heme and not tyrosyl radical is the likely culprit in prostaglandin H synthase-1 peroxidase inactivation. | 2007 | Biochemistry | pmid:17209563 |
Yeh HC et al. | Reaction mechanisms of 15-hydroperoxyeicosatetraenoic acid catalyzed by human prostacyclin and thromboxane synthases. | 2007 | Arch. Biochem. Biophys. | pmid:17459323 |
Mahipal SV et al. | Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: reactive oxygen species (ROS) mediate caspase-dependent apoptosis. | 2007 | Biochem. Pharmacol. | pmid:17517376 |
Bizzozero OA et al. | Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion. | 2007 | Neurochem. Res. | pmid:17551832 |
Gulliksson M et al. | Expression of 15-lipoxygenase type-1 in human mast cells. | 2007 | Biochim. Biophys. Acta | pmid:17662651 |
pmid:18045545 | ||||
Van Diest MJ et al. | 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1824864 |
pmid:18494609 | ||||
pmid:1872469 | ||||
Force T et al. | Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. | 1991 | J. Biol. Chem. | pmid:1900289 |
pmid:1910308 | ||||
Wecksler AT et al. | Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. | 2009 | Biochemistry | pmid:19469483 |
Hung ND et al. | Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19819343 |
Rock C and Moos PJ | Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. | 2010 Oct-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20826080 |
Weitberg AB | Hydroxy- and hydroperoxy-6,8,11,14-eicosatetraenoic acids induce sister chromatid exchanges in cultured mammalian cells. | 1990 | Am. J. Med. Sci. | pmid:2105055 |
pmid:2122182 | ||||
Andrianarison RH et al. | Positional specificity of a Lupinus albus lipoxygenase in relation to enzyme concentration and effect of a double dioxygenation product of arachidonic acid. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2123103 |
pmid:2241945 | ||||
Soumya SJ et al. | Effect of 15-lipoxygenase metabolites on angiogenesis: 15(S)-HPETE is angiostatic and 15(S)-HETE is angiogenic. | 2012 | Inflamm. Res. | pmid:22450700 |
Murota S et al. | The control of vascular endothelial cell injury. | 1990 | Ann. N. Y. Acad. Sci. | pmid:2248437 |
Kanofsky JR | Singlet oxygen production by bleomycin. A comparison with heme-containing compounds. | 1986 | J. Biol. Chem. | pmid:2428818 |
Vijil C et al. | Arachidonate 15-lipoxygenase enzyme products increase platelet aggregation and thrombin generation. | 2014 | PLoS ONE | pmid:24533104 |
Wang J et al. | Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid. | 1989 | FEBS Lett. | pmid:2494061 |
Raza H et al. | Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2500117 |
Najid A et al. | Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture. | 1989 | Cancer Lett. | pmid:2502308 |
Ng CF et al. | Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1). | 1989 | Biochim. Biophys. Acta | pmid:2503031 |
McColl SR et al. | Activation of the human neutrophil 5-lipoxygenase by exogenous arachidonic acid: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins. | 1989 | Br. J. Pharmacol. | pmid:2507084 |
Kim MR et al. | Inactivation of potato lipoxygenase by hydroperoxy acids as suicide substrates. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2511843 |
Pace-Asciak CR and Asotra S | Biosynthesis, catabolism, and biological properties of HPETEs, hydroperoxide derivatives of arachidonic acid. | 1989 | Free Radic. Biol. Med. | pmid:2514125 |
pmid:25260666 | ||||
Chansel D et al. | Modulation of renin synthesis by lipoxygenase products in cultured human mesangial cells. | 1989 | Mol. Cell. Endocrinol. | pmid:2545491 |
Garrick R et al. | Transformation of leukotriene A4 to lipoxins by rat kidney mesangial cell. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2547366 |
Smith CV and Reilly MH | Formation of pentane versus 1-pentanol in the ferrous sulfate-initiated decomposition of 15-hydroperoxyeicosatetraenoic acid in hypoxic and hyperoxic conditions. | 1989 | Biochem. Pharmacol. | pmid:2706024 |
Goodwin JS and Behrens T | Role of lipoxygenase metabolites of arachidonic acid in T cell activation. | 1988 | Ann. N. Y. Acad. Sci. | pmid:2837956 |
Shimizu T et al. | Activation of the arachidonate 5-lipoxygenase pathway in the canine basilar artery after experimental subarachnoidal hemorrhage. | 1988 | J. Neurochem. | pmid:2843605 |
Gerzer R et al. | Activation of soluble guanylate cyclase by arachidonic acid and 15-lipoxygenase products. | 1986 | Biochim. Biophys. Acta | pmid:2871867 |
pmid:28809482 | ||||
Gualde N et al. | Induction of suppressor cells from peripheral blood T cells by 15-hydroperoxyeicosatetraenoic acid (15-HPETE). | 1985 | J. Immunol. | pmid:2931484 |
Gualde N et al. | Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets. | 1985 | J. Immunol. | pmid:2981258 |
Bryant RW et al. | Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4. | 1985 | J. Biol. Chem. | pmid:2982864 |
Brash AR et al. | Investigation of the selectivity of hydrogen abstraction in the nonenzymatic formation of hydroxyeicosatetraenoic acids and leukotrienes by autoxidation. | 1985 | J. Biol. Chem. | pmid:2984196 |
Maas RL et al. | Investigation of the chemical conversion of hydroperoxyeicosatetraenoate to leukotriene epoxide using stereospecifically labeled arachidonic acid. Comparison with the enzymatic reaction. | 1985 | J. Biol. Chem. | pmid:2984197 |
Lanefelt F and Martinsson A | Ethanol dependent interaction between prostaglandins and lipoxygenase products in human peripheral lymphocytes. | 1985 | Acta Pharmacol Toxicol (Copenh) | pmid:2986412 |
Kontos HA | George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury. | 1985 | Circ. Res. | pmid:2994903 |
Fitzsimmons BJ et al. | The lipoxins. Stereochemical identification and determination of their biosynthesis. | 1985 | J. Biol. Chem. | pmid:2997152 |
pmid:2999334 | ||||
Eling TE et al. | Oxidation of glutathione to its thiyl free radical metabolite by prostaglandin H synthase. A potential endogenous substrate for the hydroperoxidase. | 1986 | J. Biol. Chem. | pmid:3007487 |
Thomas G and Ramwell P | Induction of vascular relaxation by hydroperoxides. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3021120 |
pmid:3024570 | ||||
Kulmacz RJ et al. | Heme spin states and peroxide-induced radical species in prostaglandin H synthase. | 1987 | J. Biol. Chem. | pmid:3038886 |
Mayer B et al. | Possible inhibitory function of endogenous 15-hydroperoxyeicosatetraenoic acid on prostacyclin formation in bovine aortic endothelial cells. | 1986 | Biochim. Biophys. Acta | pmid:3081039 |
Esterbauer H et al. | Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation. | 1986 | Biochim. Biophys. Acta | pmid:3081043 |
Humes JL et al. | Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids. | 1986 | Biochem. J. | pmid:3082323 |
Serhan CN et al. | On the stereochemistry and biosynthesis of lipoxin B. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3083410 |
Ueda N et al. | Purification of arachidonate 5-lipoxygenase from porcine leukocytes and its reactivity with hydroperoxyeicosatetraenoic acids. | 1986 | J. Biol. Chem. | pmid:3086322 |
Hamberg M et al. | Novel biological transformations of 15-Ls-hydroperoxy-5,8,11,13-eicosatetraenoic acid. | 1986 | Biochim. Biophys. Acta | pmid:3089290 |
Rouzer CA and Samuelsson B | The importance of hydroperoxide activation for the detection and assay of mammalian 5-lipoxygenase. | 1986 | FEBS Lett. | pmid:3089841 |
pmid:3092738 |