| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
Total
1
15-hpete
15-hpete is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 15-hpete
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-hpete
NCBI Entrez Crosslinks
All references with 15-hpete
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pfister SL et al. | Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. | 1998 | J. Biol. Chem. | pmid:9812980 |
| Maccarrone M et al. | Lipoxygenase products induce ultraweak light emission from human erythroleukemia cells. | 1997 Nov-Dec | J. Biolumin. Chemilumin. | pmid:9509336 |
| Kato Y and Osawa T | Detection of oxidized phospholipid-protein adducts using anti-15-hydroperoxyeicosatetraenoic acid-modified protein antibody: contribution of esterified fatty acid-protein adduct to oxidative modification of LDL. | 1998 | Arch. Biochem. Biophys. | pmid:9500842 |
| Tsai Al et al. | Structural characterization of arachidonyl radicals formed by prostaglandin H synthase-2 and prostaglandin H synthase-1 reconstituted with mangano protoporphyrin IX. | 1998 | J. Biol. Chem. | pmid:9461572 |
| Riccio MM et al. | The effect of 15-HPETE on airway responsiveness and pulmonary cell recruitment in rabbits. | 1997 | Br. J. Pharmacol. | pmid:9313932 |
| Landino LM et al. | Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation. | 1997 | J. Biol. Chem. | pmid:9261177 |
| Calzada C et al. | Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation. | 1997 | Biochem. J. | pmid:9230133 |
| Foley TD | 5-HPETE is a potent inhibitor of neuronal Na+, K(+)-ATPase activity. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9199200 |
| Augustin AJ et al. | Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases. | 1997 | Br J Ophthalmol | pmid:9135410 |
| Grechkin AN et al. | On the mechanism of biosynthesis of divinyl ether oxylipins by enzyme from garlic bulbs. | 1997 | Eur. J. Biochem. | pmid:9128734 |
| Tsai Al et al. | Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX. | 1997 | J. Biol. Chem. | pmid:9083007 |
| Kühn H | Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)XY-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)XY-9Z,11E-octadecadienoic acid. | 1996 | Prog. Lipid Res. | pmid:9082450 |
| Ferrante JV et al. | Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production. | 1997 | J. Clin. Invest. | pmid:9077554 |
| Rao GN et al. | Role of hydroperoxyeicosatetraenoic acids in oxidative stress-induced activating protein 1 (AP-1) activity. | 1996 | J. Biol. Chem. | pmid:8910370 |
| Van Diest MJ et al. | Influence of hypercholesterolaemia on the reactivity of isolated rabbit arteries to 15-lipoxygenase metabolites of arachidonic acid: comparison with platelet-derived agents and vasodilators. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8848433 |
| Yamazaki T et al. | 15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis. | 1996 | Endocrinology | pmid:8770885 |
| pmid:8655602 | ||||
| Tang DG et al. | Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8643560 |
| Landino LM and Marnett LJ | Mechanism of hydroperoxide reduction by mangano-prostaglandin endoperoxide synthase. | 1996 | Biochemistry | pmid:8611568 |
| Kishimoto K et al. | Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative. | 1996 | Biochim. Biophys. Acta | pmid:8608163 |
| Iliou JP et al. | Monohydroperoxidized fatty acids but not 4-hydroxynonenal induced acute cardiac cell damage. | 1995 | Free Radic. Biol. Med. | pmid:8582650 |
| pmid:8555216 | ||||
| Van Diest MJ et al. | Vascular interaction between 5-hydroxytryptamine and 15-lipoxygenase metabolites of arachidonic acid. | 1993 | Eur. J. Pharmacol. | pmid:8453981 |
| Kiran Kumar YV et al. | Differential effects of 15-HPETE and 15-HETE on BHK-21 cell proliferation and macromolecular composition. | 1993 | Biochim. Biophys. Acta | pmid:8384883 |
| Calzada C and Rice-Evans C | Ruptured erythrocytes inhibit the oxidation of membranes by 15-hydroperoxy-eicosatetraenoic acid. | 1993 | FEBS Lett. | pmid:8354383 |
| Kühn H et al. | Overexpression, purification and characterization of human recombinant 15-lipoxygenase. | 1993 | Biochim. Biophys. Acta | pmid:8334154 |
| Sandstrom PA et al. | Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency. | 1994 | J. Biol. Chem. | pmid:8288627 |
| Tebbey PW and Buttke TM | Independent arachidonic acid-mediated gene regulatory pathways in lymphocytes. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8102055 |
| Vaidyanathan VV and Sastry PS | Preparation of hydroperoxy fatty acids. | 1994 | Anal. Biochem. | pmid:8080099 |
| Bourdeau A et al. | Effects of lipoxygenase products of arachidonate metabolism on parathyroid hormone secretion. | 1994 | Endocrinology | pmid:8070353 |
| Kodaman PH et al. | Lipid hydroperoxides evoke antigonadotropic and antisteroidogenic activity in rat luteal cells. | 1994 | Endocrinology | pmid:7988463 |
| MacMillan DK et al. | Eosinophil 15-lipoxygenase is a leukotriene A4 synthase. | 1994 | J. Biol. Chem. | pmid:7929400 |
| pmid:7825847 | ||||
| Matsuda H et al. | Pharmacodynamics of 15(S)-hydroperoxyeicosatetraenoic (15-HPETE) and 15(S)-hydroxyeicosatetraenoic acid (15-HETE) in isolated arteries from guinea pig, rabbit, rat and human. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791089 |
| Sandstrom PA et al. | Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. | 1995 | FEBS Lett. | pmid:7774717 |
| Terao J et al. | Effects of rat bile-pancreatic juice on Fe2+ induced peroxidation of phospholipids. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7765976 |
| Björnstedt M et al. | Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. | 1995 | J. Biol. Chem. | pmid:7744824 |
| Mochizuki-Oda N et al. | Arachidonic acid activates cation channels in bovine adrenal chromaffin cells. | 1993 | J. Neurochem. | pmid:7693870 |
| pmid:7492586 | ||||
| Bates EJ et al. | Inhibitory effects of arachidonic acid (20:4,n-6) and its monohydroperoxy- and hydroxy-metabolites on procoagulant activity in endothelial cells. | 1995 | Atherosclerosis | pmid:7488327 |
| pmid:7463137 | ||||
| pmid:7384539 | ||||
| Kobayashi M et al. | [Effects of 15-hydroperoxy arachidonic acid and non-purified hydroperoxides from arachidonic acid to rabbit blood vessels (author's transl)]. | 1980 | Nihon Ronen Igakkai Zasshi | pmid:7373935 |
| pmid:7342109 | ||||
| Lagarde M et al. | Inhibition of thrombin-induced platelet arachidonic acid release by 15-hydroperoxy-arachidonic acid. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7259783 |
| pmid:7191704 | ||||
| pmid:7140815 | ||||
| Patrono C and Pugliese F | The involvement of arachidonic acid metabolism in the control of renin release. | 1980 Apr-Jun | J. Endocrinol. Invest. | pmid:6993550 |
| pmid:6992239 | ||||
| Vanderhoek JY et al. | Regulation of leukocyte and platelet lipoxygenases by hydroxyeicosanoids. | 1982 | Biochem. Pharmacol. | pmid:6816247 |
| Koide T et al. | Possible mechanisms of 15-hydroperoxyarachidonic acid-induced contraction of the canine basilar artery in vitro. | 1982 | J. Pharmacol. Exp. Ther. | pmid:6804622 |
| Bryant RW et al. | Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid. | 1982 | J. Biol. Chem. | pmid:6804460 |
| Capdevila J et al. | Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6801662 |
| Siegel MI | Effect of non-steroidal anti-inflammatory drugs on arachidonic acid metabolism. | 1981 | Headache | pmid:6796546 |
| pmid:6784932 | ||||
| Hong SL et al. | Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells. | 1980 | J. Biol. Chem. | pmid:6776101 |
| pmid:6775351 | ||||
| pmid:6728899 | ||||
| RÃ¥dmark O et al. | Hemoprotein catalysis of leukotriene formation. | 1984 | Biochim. Biophys. Acta | pmid:6696937 |
| Bösterling B and Trudell JR | Production of 5- and 15-hydroperoxyeicosatetraenoic acid from arachidonic acid by halothane-free radicals generated by UV-irradiation. | 1984 | Anesthesiology | pmid:6696254 |
| Davies JA and Menys VC | Effect of dazoxiben on platelet-vessel wall interaction. | 1983 | Br J Clin Pharmacol | pmid:6681703 |
| Walters FP et al. | Oxidation of myoglobin in isolated adult rat cardiac myocytes by 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid. | 1983 | FEBS Lett. | pmid:6641945 |
| Iwaoka T and Tabata F | Chemiluminescent assay of lipid peroxide in plasma using cytochrome c heme peptide. | 1984 | FEBS Lett. | pmid:6500062 |
| Suzuki Y et al. | Gamma-aminobutyric acid-induced contraction of the dog basilar artery. | 1984 | Pharmacology | pmid:6463098 |
| Hopkins NK et al. | Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells. | 1984 | J. Biol. Chem. | pmid:6438089 |
| Christman CW et al. | Effects of 15-hydroperoxy-eicosatetraenoic acid (15-HPETE) on cerebral arterioles of cats. | 1984 | Am. J. Physiol. | pmid:6437243 |
| Marnett LJ et al. | Mechanism of the stimulation of prostaglandin H synthase and prostacyclin synthase by the antithrombotic and antimetastatic agent, nafazatrom. | 1984 | Mol. Pharmacol. | pmid:6434940 |
| Serhan CN et al. | Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6422933 |
| Elhai J and Scandella CJ | Arachidonic acid and other fatty acids inhibit secretion from sea urchin eggs. | 1983 | Exp. Cell Res. | pmid:6414832 |
| Kent RS et al. | Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta. | 1983 | J. Clin. Invest. | pmid:6409932 |
| pmid:6402031 | ||||
| Beetens JR and Herman AG | Vitamin C increases the formation of prostacyclin by aortic rings from various species and neutralizes the inhibitory effect of 15-hydroperoxy-arachidonic acid. | 1983 | Br. J. Pharmacol. | pmid:6360278 |
| Furukawa K et al. | The restorative action of coenzyme Q10 in 2,4-dinitrophenol-depressed electrical and contractile activities of guinea-pig heart. | 1983 | J. Mol. Cell. Cardiol. | pmid:6355490 |
| pmid:6353402 | ||||
| McCarty M | Can dietary selenium reduce leukotriene production? | 1984 | Med. Hypotheses | pmid:6323934 |
| Trudell JR et al. | Hypoxia potentiates killing of hepatocyte monolayers by leukotrienes, hydroperoxyeicosatetraenoic acids, or calcium ionophore A23187. | 1984 | Biochim. Biophys. Acta | pmid:6322862 |
| Maas RL and Brash AR | Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes. | 1983 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6304687 |
| Sok DE et al. | Mechanisms of leukotriene formation: hemoglobin-catalyzed transformation of 15-HPETE into 8,15-DiHETE and 14,15-DiHETE isomers. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6301444 |
| Nagy L et al. | Complement receptor enhancement and chemotaxis of human neutrophils and eosinophils by leukotrienes and other lipoxygenase products. | 1982 | Clin. Exp. Immunol. | pmid:6282507 |
| Sok DE et al. | Enzymatic formation of 14,15-leukotriene A and C(14)-sulfur-linked peptides. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6280711 |
| Higgs GA et al. | The inflammatory effects of hydroperoxy and hydroxy acid products of arachidonate lipoxygenase in rabbit skin. | 1981 | Br. J. Pharmacol. | pmid:6274465 |
| Naccache PH et al. | Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils. | 1981 | J. Clin. Invest. | pmid:6262382 |
| Goetzl EJ et al. | Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid. | 1980 | Prostaglandins | pmid:6247746 |
| Folkerts G et al. | Induction in guinea-pigs of airway hyperreactivity and decreased lung beta-adrenoceptor number by 15-hydroperoxy-arachidonic acid. | 1983 | Br. J. Pharmacol. | pmid:6100841 |
| Brash AR et al. | On the mechanism of biosynthesis of 5- and 15-series leukotrienes. | 1984 | J. Allergy Clin. Immunol. | pmid:6088609 |
| Trachte GJ et al. | Potent constriction of cat coronary arteries by hydroperoxides of arachidonic acid and its blockade by anti-inflammatory agents. | 1979 | Prostaglandins | pmid:547310 |
| Koide T et al. | Alterations of the eicosanoid synthetic capacity of rat brain microvessels following ischemia: relevance to ischemic brain edema. | 1985 | J. Neurochem. | pmid:3964837 |
| Takahashi M et al. | Vascular effects of 15-hydroperoxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid on canine arteries. | 1985 | Jpn. J. Pharmacol. | pmid:3925206 |
| Johnson HG et al. | 15-Hydroxyeicosatetraenoic acid is a potent inflammatory mediator and agonist of canine tracheal mucus secretion. | 1985 | Am. Rev. Respir. Dis. | pmid:3923884 |
| Lundberg U et al. | Appearance of an arachidonic acid 15-lipoxygenase pathway upon differentiation of the human promyelocytic cell-line HL-60. | 1985 | FEBS Lett. | pmid:3922792 |
| Eling TE et al. | The formation of aminopyrine cation radical by the peroxidase activity of prostaglandin H synthase and subsequent reactions of the radical. | 1985 | J. Biol. Chem. | pmid:3918042 |
| pmid:3917545 | ||||
| Weiss RH et al. | Transformation of an arachidonic acid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450. | 1987 | Arch. Biochem. Biophys. | pmid:3813540 |
| Dahlén SE et al. | Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. | 1987 | Acta Physiol. Scand. | pmid:3630737 |
| pmid:3426609 | ||||
| Cashman JR et al. | Inhibition of human leukocyte 5-lipoxygenase by 15-HPETE and related eicosanoids. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3415693 |
| pmid:3382013 | ||||
| Ueda N and Yamamoto S | The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes. | 1988 | J. Biol. Chem. | pmid:3338999 |
| Gut J et al. | Quantification of 5- and 15-HPETE's by direct chemical ionization mass spectrometry. | 1987 | Free Radic. Biol. Med. | pmid:3319797 |
| Antonipillai I et al. | The inhibitory role of 12- and 15-lipoxygenase products on renin release. | 1987 | Hypertension | pmid:3298043 |