15-hpete

15-hpete is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 15-hpete

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-hpete

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Total 1

NCBI Entrez Crosslinks

All references with 15-hpete

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Authors Title Published Journal PubMed Link
Piomelli D The ligand that came from within. 2001 Trends Pharmacol. Sci. pmid:11165666
Yoshinaga M et al. 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. 2004 Prostaglandins Other Lipid Mediat. pmid:15165036
Kalyankrishna S et al. Arachidonic acid-derived oxidation products initiate apoptosis in vascular smooth muscle cells. 2002 Prostaglandins Other Lipid Mediat. pmid:12428675
Hung ND et al. Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis. 2009 Prostaglandins Other Lipid Mediat. pmid:19819343
Van Diest MJ et al. Influence of hypercholesterolaemia on the reactivity of isolated rabbit arteries to 15-lipoxygenase metabolites of arachidonic acid: comparison with platelet-derived agents and vasodilators. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8848433
Rock C and Moos PJ Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. 2010 Oct-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:20826080
Sakai K et al. 12-Hydroperoxyeicosatetraenoic acid (12-HPETE) and 15-HPETE stimulate melatonin synthesis in rat pineals. 1988 Prostaglandins pmid:3187058
Trachte GJ et al. Potent constriction of cat coronary arteries by hydroperoxides of arachidonic acid and its blockade by anti-inflammatory agents. 1979 Prostaglandins pmid:547310
Van Diest MJ et al. Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels. 1986 Prostaglandins pmid:3094100
Goetzl EJ et al. Unique aspects of the modulation of human neutrophil function by 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid. 1980 Prostaglandins pmid:6247746
Kühn H Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)XY-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)XY-9Z,11E-octadecadienoic acid. 1996 Prog. Lipid Res. pmid:9082450
Maas RL and Brash AR Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes. 1983 Proc. Natl. Acad. Sci. U.S.A. pmid:6304687
Capdevila J et al. Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6801662
Hwang SW et al. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10823958
Serhan CN et al. On the stereochemistry and biosynthesis of lipoxin B. 1986 Proc. Natl. Acad. Sci. U.S.A. pmid:3083410
Tang DG et al. Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643560
Vijil C et al. Arachidonate 15-lipoxygenase enzyme products increase platelet aggregation and thrombin generation. 2014 PLoS ONE pmid:24533104
Suzuki Y et al. Gamma-aminobutyric acid-induced contraction of the dog basilar artery. 1984 Pharmacology pmid:6463098
d'Ischia M et al. Interactions of nitric oxide with lipid peroxidation products under aerobic conditions: inhibitory effects on the formation of malondialdehyde and related thiobarbituric acid-reactive substances. 2000 Nitric Oxide pmid:10733868
Kobayashi M et al. [Effects of 15-hydroperoxy arachidonic acid and non-purified hydroperoxides from arachidonic acid to rabbit blood vessels (author's transl)]. 1980 Nihon Ronen Igakkai Zasshi pmid:7373935