| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
Total
1
15-hpete
15-hpete is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 15-hpete
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-hpete
NCBI Entrez Crosslinks
All references with 15-hpete
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tsai Al et al. | Structural characterization of arachidonyl radicals formed by prostaglandin H synthase-2 and prostaglandin H synthase-1 reconstituted with mangano protoporphyrin IX. | 1998 | J. Biol. Chem. | pmid:9461572 |
| Pfister SL et al. | Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. | 1998 | J. Biol. Chem. | pmid:9812980 |
| Brash AR et al. | Investigation of the selectivity of hydrogen abstraction in the nonenzymatic formation of hydroxyeicosatetraenoic acids and leukotrienes by autoxidation. | 1985 | J. Biol. Chem. | pmid:2984196 |
| Rao GN et al. | Role of hydroperoxyeicosatetraenoic acids in oxidative stress-induced activating protein 1 (AP-1) activity. | 1996 | J. Biol. Chem. | pmid:8910370 |
| Bryant RW et al. | Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid. | 1982 | J. Biol. Chem. | pmid:6804460 |
| Yu MK et al. | Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes. | 2004 | J. Biol. Chem. | pmid:15123685 |
| Björnstedt M et al. | Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. | 1995 | J. Biol. Chem. | pmid:7744824 |
| MacMillan DK et al. | Eosinophil 15-lipoxygenase is a leukotriene A4 synthase. | 1994 | J. Biol. Chem. | pmid:7929400 |
| Sandstrom PA et al. | Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency. | 1994 | J. Biol. Chem. | pmid:8288627 |
| Tsai Al et al. | Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX. | 1997 | J. Biol. Chem. | pmid:9083007 |
| Force T et al. | Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. | 1991 | J. Biol. Chem. | pmid:1900289 |
| Bryant RW et al. | Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4. | 1985 | J. Biol. Chem. | pmid:2982864 |
| Hong SL et al. | Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells. | 1980 | J. Biol. Chem. | pmid:6776101 |
| Maas RL et al. | Investigation of the chemical conversion of hydroperoxyeicosatetraenoate to leukotriene epoxide using stereospecifically labeled arachidonic acid. Comparison with the enzymatic reaction. | 1985 | J. Biol. Chem. | pmid:2984197 |
| Eling TE et al. | The formation of aminopyrine cation radical by the peroxidase activity of prostaglandin H synthase and subsequent reactions of the radical. | 1985 | J. Biol. Chem. | pmid:3918042 |
| Hopkins NK et al. | Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells. | 1984 | J. Biol. Chem. | pmid:6438089 |
| Landino LM et al. | Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation. | 1997 | J. Biol. Chem. | pmid:9261177 |
| Coffa G et al. | On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant. | 2005 | J. Biol. Chem. | pmid:16157595 |
| Maccarrone M et al. | Lipoxygenase products induce ultraweak light emission from human erythroleukemia cells. | 1997 Nov-Dec | J. Biolumin. Chemilumin. | pmid:9509336 |
| Naccache PH et al. | Mono- and dihydroxyeicosatetraenoic acids alter calcium homeostasis in rabbit neutrophils. | 1981 | J. Clin. Invest. | pmid:6262382 |
| Kent RS et al. | Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta. | 1983 | J. Clin. Invest. | pmid:6409932 |
| Ferrante JV et al. | Altered responses of human macrophages to lipopolysaccharide by hydroperoxy eicosatetraenoic acid, hydroxy eicosatetraenoic acid, and arachidonic acid. Inhibition of tumor necrosis factor production. | 1997 | J. Clin. Invest. | pmid:9077554 |
| Patrono C and Pugliese F | The involvement of arachidonic acid metabolism in the control of renin release. | 1980 Apr-Jun | J. Endocrinol. Invest. | pmid:6993550 |
| Gualde N et al. | Induction of suppressor cells from peripheral blood T cells by 15-hydroperoxyeicosatetraenoic acid (15-HPETE). | 1985 | J. Immunol. | pmid:2931484 |
| Balboa MA et al. | Amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A2 is regulated by cytosolic phospholipase A2-derived hydroperoxyeicosatetraenoic acid. | 2003 | J. Immunol. | pmid:12847271 |
| Ferrante JV and Ferrante A | Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line. | 2005 | J. Immunol. | pmid:15749845 |
| Moghaddami N et al. | Unique effect of arachidonic acid on human neutrophil TNF receptor expression: up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A2. | 2003 | J. Immunol. | pmid:12928414 |
| Gualde N et al. | Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets. | 1985 | J. Immunol. | pmid:2981258 |
| Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1. | 2000 | J. Lipid Res. | pmid:10974056 |
| Navab M et al. | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3. | 2000 | J. Lipid Res. | pmid:10974057 |
| Furukawa K et al. | The restorative action of coenzyme Q10 in 2,4-dinitrophenol-depressed electrical and contractile activities of guinea-pig heart. | 1983 | J. Mol. Cell. Cardiol. | pmid:6355490 |
| Shimizu T et al. | Activation of the arachidonate 5-lipoxygenase pathway in the canine basilar artery after experimental subarachnoidal hemorrhage. | 1988 | J. Neurochem. | pmid:2843605 |
| Mochizuki-Oda N et al. | Arachidonic acid activates cation channels in bovine adrenal chromaffin cells. | 1993 | J. Neurochem. | pmid:7693870 |
| Koide T et al. | Alterations of the eicosanoid synthetic capacity of rat brain microvessels following ischemia: relevance to ischemic brain edema. | 1985 | J. Neurochem. | pmid:3964837 |
| Uotila P et al. | Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta. | 1987 | J. Pharmacol. Exp. Ther. | pmid:3116200 |
| Koide T et al. | Possible mechanisms of 15-hydroperoxyarachidonic acid-induced contraction of the canine basilar artery in vitro. | 1982 | J. Pharmacol. Exp. Ther. | pmid:6804622 |
| Matsuda H et al. | Pharmacodynamics of 15(S)-hydroperoxyeicosatetraenoic (15-HPETE) and 15(S)-hydroxyeicosatetraenoic acid (15-HETE) in isolated arteries from guinea pig, rabbit, rat and human. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791089 |
| Van Diest MJ et al. | 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1824864 |
| Takahashi M et al. | Vascular effects of 15-hydroperoxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid on canine arteries. | 1985 | Jpn. J. Pharmacol. | pmid:3925206 |
| Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
| McCarty M | Can dietary selenium reduce leukotriene production? | 1984 | Med. Hypotheses | pmid:6323934 |
| Chansel D et al. | Modulation of renin synthesis by lipoxygenase products in cultured human mesangial cells. | 1989 | Mol. Cell. Endocrinol. | pmid:2545491 |
| Marnett LJ et al. | Mechanism of the stimulation of prostaglandin H synthase and prostacyclin synthase by the antithrombotic and antimetastatic agent, nafazatrom. | 1984 | Mol. Pharmacol. | pmid:6434940 |
| Bizzozero OA et al. | Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion. | 2007 | Neurochem. Res. | pmid:17551832 |
| Rabier M et al. | 15-Lipoxygenase products stimulate prolactin secretion from a cloned strain of rat pituitary cells. | 1988 | Neuroendocrinology | pmid:3131692 |
| Kobayashi M et al. | [Effects of 15-hydroperoxy arachidonic acid and non-purified hydroperoxides from arachidonic acid to rabbit blood vessels (author's transl)]. | 1980 | Nihon Ronen Igakkai Zasshi | pmid:7373935 |
| d'Ischia M et al. | Interactions of nitric oxide with lipid peroxidation products under aerobic conditions: inhibitory effects on the formation of malondialdehyde and related thiobarbituric acid-reactive substances. | 2000 | Nitric Oxide | pmid:10733868 |
| Suzuki Y et al. | Gamma-aminobutyric acid-induced contraction of the dog basilar artery. | 1984 | Pharmacology | pmid:6463098 |
| Vijil C et al. | Arachidonate 15-lipoxygenase enzyme products increase platelet aggregation and thrombin generation. | 2014 | PLoS ONE | pmid:24533104 |
| Hwang SW et al. | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10823958 |