| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
Total
1
15-hpete
15-hpete is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 724 references associated with 15-hpete in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 15-hpete
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-hpete
NCBI Entrez Crosslinks
All references with 15-hpete
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Wu G et al. | A mechanistic study of self-inactivation of the peroxidase activity in prostaglandin H synthase-1. | 1999 | J. Biol. Chem. | pmid:10092596 |
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| Cao YZ et al. | Altered eicosanoid biosynthesis in selenium-deficient endothelial cells. | 2000 | Free Radic. Biol. Med. | pmid:10699749 |
| d'Ischia M et al. | Interactions of nitric oxide with lipid peroxidation products under aerobic conditions: inhibitory effects on the formation of malondialdehyde and related thiobarbituric acid-reactive substances. | 2000 | Nitric Oxide | pmid:10733868 |
| Whalen MM et al. | Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. | 1999 | Cell. Physiol. Biochem. | pmid:10749996 |
| Hwang SW et al. | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10823958 |
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| O'Donnell VB et al. | Catalytic consumption of nitric oxide by prostaglandin H synthase-1 regulates platelet function. | 2000 | J. Biol. Chem. | pmid:10993875 |
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| Prabhu KS et al. | Microsomal glutathione S-transferase A1-1 with glutathione peroxidase activity from sheep liver: molecular cloning, expression and characterization. | 2001 | Biochem. J. | pmid:11716762 |
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| Kalyankrishna S et al. | Arachidonic acid-derived oxidation products initiate apoptosis in vascular smooth muscle cells. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428675 |
| Baker LM and Poole LB | Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. | 2003 | J. Biol. Chem. | pmid:12514184 |
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| Manini P et al. | Ni2+ enhances Fe2+/peroxide-induced oxidation of arachidonic acid and formation of geno/cytotoxic 4-hydroxynonenal: a possible contributory mechanism in nickel toxicity and allergenicity. | 2003 | Biochim. Biophys. Acta | pmid:12667605 |
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| Cavalieri B et al. | Ischaemic preconditioning modulates the activity of Kupffer cells during in vivo reperfusion injury of rat liver. | 2003 | Cell Biochem. Funct. | pmid:14624466 |
| Trang T et al. | Involvement of spinal lipoxygenase metabolites in hyperalgesia and opioid tolerance. | 2004 | Eur. J. Pharmacol. | pmid:15102529 |
| Yu MK et al. | Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes. | 2004 | J. Biol. Chem. | pmid:15123685 |
| Yoshinaga M et al. | 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165036 |
| pmid:1520701 | ||||
| pmid:1523215 | ||||
| Clark SR et al. | Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. | 2005 | Biochem. J. | pmid:15461587 |
| Ruddat VC et al. | Tryptophan 500 and arginine 707 define product and substrate active site binding in soybean lipoxygenase-1. | 2004 | Biochemistry | pmid:15476400 |
| pmid:15650406 | ||||
| pmid:15723435 | ||||
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| pmid:15967159 | ||||
| Coffa G et al. | On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant. | 2005 | J. Biol. Chem. | pmid:16157595 |
| Trigona WL et al. | Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells. | 2006 | Biochem. J. | pmid:16209660 |
| Iwahashi H et al. | Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s. | 1991 | Biochem. J. | pmid:1646600 |
| Wu G et al. | Oxyferryl heme and not tyrosyl radical is the likely culprit in prostaglandin H synthase-1 peroxidase inactivation. | 2007 | Biochemistry | pmid:17209563 |
| Yeh HC et al. | Reaction mechanisms of 15-hydroperoxyeicosatetraenoic acid catalyzed by human prostacyclin and thromboxane synthases. | 2007 | Arch. Biochem. Biophys. | pmid:17459323 |
| Mahipal SV et al. | Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: reactive oxygen species (ROS) mediate caspase-dependent apoptosis. | 2007 | Biochem. Pharmacol. | pmid:17517376 |
| Bizzozero OA et al. | Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion. | 2007 | Neurochem. Res. | pmid:17551832 |
| Gulliksson M et al. | Expression of 15-lipoxygenase type-1 in human mast cells. | 2007 | Biochim. Biophys. Acta | pmid:17662651 |
| pmid:18045545 | ||||
| Van Diest MJ et al. | 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1824864 |
| pmid:18494609 | ||||
| pmid:1872469 | ||||
| Force T et al. | Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. | 1991 | J. Biol. Chem. | pmid:1900289 |
| pmid:1910308 | ||||
| Wecksler AT et al. | Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. | 2009 | Biochemistry | pmid:19469483 |
| Hung ND et al. | Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19819343 |
| Rock C and Moos PJ | Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. | 2010 Oct-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20826080 |
| Weitberg AB | Hydroxy- and hydroperoxy-6,8,11,14-eicosatetraenoic acids induce sister chromatid exchanges in cultured mammalian cells. | 1990 | Am. J. Med. Sci. | pmid:2105055 |
| pmid:2122182 | ||||
| Andrianarison RH et al. | Positional specificity of a Lupinus albus lipoxygenase in relation to enzyme concentration and effect of a double dioxygenation product of arachidonic acid. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2123103 |
| pmid:2241945 | ||||
| Soumya SJ et al. | Effect of 15-lipoxygenase metabolites on angiogenesis: 15(S)-HPETE is angiostatic and 15(S)-HETE is angiogenic. | 2012 | Inflamm. Res. | pmid:22450700 |
| Murota S et al. | The control of vascular endothelial cell injury. | 1990 | Ann. N. Y. Acad. Sci. | pmid:2248437 |
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| Wang J et al. | Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid. | 1989 | FEBS Lett. | pmid:2494061 |
| Raza H et al. | Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2500117 |
| Najid A et al. | Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture. | 1989 | Cancer Lett. | pmid:2502308 |
| Ng CF et al. | Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1). | 1989 | Biochim. Biophys. Acta | pmid:2503031 |
| McColl SR et al. | Activation of the human neutrophil 5-lipoxygenase by exogenous arachidonic acid: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins. | 1989 | Br. J. Pharmacol. | pmid:2507084 |
| Kim MR et al. | Inactivation of potato lipoxygenase by hydroperoxy acids as suicide substrates. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2511843 |
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| pmid:25260666 | ||||
| Chansel D et al. | Modulation of renin synthesis by lipoxygenase products in cultured human mesangial cells. | 1989 | Mol. Cell. Endocrinol. | pmid:2545491 |
| Garrick R et al. | Transformation of leukotriene A4 to lipoxins by rat kidney mesangial cell. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2547366 |
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| Brash AR et al. | Investigation of the selectivity of hydrogen abstraction in the nonenzymatic formation of hydroxyeicosatetraenoic acids and leukotrienes by autoxidation. | 1985 | J. Biol. Chem. | pmid:2984196 |
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| Mayer B et al. | Possible inhibitory function of endogenous 15-hydroperoxyeicosatetraenoic acid on prostacyclin formation in bovine aortic endothelial cells. | 1986 | Biochim. Biophys. Acta | pmid:3081039 |
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