(6e,8z,11z,13e)-5,15-dihydroxyeicosa-6,8,11,13-tetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-eicosatetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-icosatetraenoic acid

(6e,8z,11z,13e)-5,15-dihydroxyeicosa-6,8,11,13-tetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-eicosatetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-icosatetraenoic acid is a lipid of Fatty Acyls (FA) class.

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Current reference collection contains 16 references associated with (6e,8z,11z,13e)-5,15-dihydroxyeicosa-6,8,11,13-tetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-eicosatetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-icosatetraenoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with (6e,8z,11z,13e)-5,15-dihydroxyeicosa-6,8,11,13-tetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-eicosatetraenoic acid;5,15-dihydroxy-6e,8z,11z,13e-icosatetraenoic acid

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Authors Title Published Journal PubMed Link
Yi X et al. Interactions Among CYP2C8, EPHX2, and CYP4A11 Variants and CYP Plasma Metabolite Levels in Ischemic Stroke. 2016 J. Atheroscler. Thromb. pmid:27087514
Tejera N et al. COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes. 2012 J. Lipid Res. pmid:22068350
Serhan CN et al. Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. 2003 J. Immunol. pmid:14662892
Dadaian M and Westlund P Albumin modifies the metabolism of hydroxyeicosatetraenoic acids via 12-lipoxygenase in human platelets. 1999 J. Lipid Res. pmid:10224163
Chavis C et al. 5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors. 1996 J. Exp. Med. pmid:8666921
Petrich K et al. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action. 1996 Biochem. J. pmid:8615788
Vonakis BM and Vanderhoek JY 15-Hydroxyeicosatetraenoic acid (15-HETE) receptors. Involvement in the 15-HETE-induced stimulation of the cryptic 5-lipoxygenase in PT-18 mast/basophil cells. 1992 J. Biol. Chem. pmid:1331094
Costello PB et al. Lipoxygenase products in inflammatory synovial fluids and other exudates. 1992 Ann. Rheum. Dis. pmid:1334643
McDonald PP et al. Activation of the human neutrophil 5-lipoxygenase by leukotriene B4. 1992 Br. J. Pharmacol. pmid:1330161
Nichols RC and Vanderhoek JY 5-Hydroxyeicosanoids selectively stimulate the human neutrophil 15-lipoxygenase to use endogenous substrate. 1990 J. Exp. Med. pmid:2154526

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