Monoethyl maleate

Monoethyl maleate is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1650 references associated with Monoethyl maleate in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Monoethyl maleate

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Monoethyl maleate

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Stomach Ulcer D013276 75 associated lipids
Total 3

All references with Monoethyl maleate

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Authors Title Published Journal PubMed Link
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Videla LA and Villena MI Effect of ethanol, acetaldehyde and acetate on the antioxidant-sensitive respiration in the perfused rat liver: influence of fasting and diethylmaleate treatment. 1986 May-Jun Alcohol pmid:3741611
Casini AF et al. Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis. 1985 Am. J. Pathol. pmid:3970139
Robert A et al. Role of glutathione in gastric mucosal cytoprotection. 1984 Am. J. Physiol. pmid:6591806
Forman HJ and Skelton DC Protection of alveolar macrophages from hyperoxia by gamma-glutamyl transpeptidase. 1990 Am. J. Physiol. pmid:1974390
Deneke SM et al. Increase in endothelial cell glutathione and precursor amino acid uptake by diethyl maleate and hyperoxia. 1989 Am. J. Physiol. pmid:2801955
Rao RK et al. Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:10915642
Singh R et al. Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501438
Oba T et al. Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca2+ release from sarcoplasmic reticulum. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:17982019
Ghosh S et al. Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15805231
Spiess PC et al. Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate. 2010 Am. J. Respir. Cell Mol. Biol. pmid:19843705
Nordström G et al. Effects of ischemia and reperfusion on protein synthesis in livers with different glutathione levels. 1990 Ann. Surg. pmid:2294851
Sáez GT et al. Effects of glutathione depletion on gluconeogenesis in isolated hepatocytes. 1985 Arch. Biochem. Biophys. pmid:4026324
Duval DL et al. Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione. 1995 Arch. Biochem. Biophys. pmid:7532384
Zhang JG et al. Mitochondrial electron transport inhibitors cause lipid peroxidation-dependent and -independent cell death: protective role of antioxidants. 2001 Arch. Biochem. Biophys. pmid:11516165
Coleman MD et al. Effects of lipoic acid and dihydrolipoic acid on 4-aminophenol-mediated erythrocytic toxicity in vitro. 2006 Basic Clin. Pharmacol. Toxicol. pmid:16930295
Sato H et al. Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide. 1995 Biochem. J. pmid:7654193
Dicker E and Cederbaum AI Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl maleate and phorone in vivo and in vitro. Implications for formaldehyde metabolism. 1986 Biochem. J. pmid:3827870
Esposito F et al. Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion. 1994 Biochem. J. pmid:7519845
Maines MD Effect of allylisopropylacetamide on glutathione metabolism in the rat liver. The possible role of glutathione in the induction of 5-aminolaevulinate synthase. 1981 Biochem. J. pmid:6118139
Cai J et al. Differential regulation of gamma-glutamylcysteine synthetase heavy and light subunit gene expression. 1997 Biochem. J. pmid:9337864
Tipnis SR et al. Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistance. 1999 Biochem. J. pmid:9895302
Savini I et al. Dehydroascorbic acid uptake in a human keratinocyte cell line (HaCaT) is glutathione-independent. 2000 Biochem. J. pmid:10642526
Bottje WG et al. Prostacyclin elevation following glutathione depletion in vivo. Possible threshold dependency in liver and lung. 1993 Biochem. Pharmacol. pmid:8216344
Koizumi T et al. Inhibitory effect of an intracellular glutathione on delta 12-prostaglandin J2-induced protein syntheses in porcine aortic endothelial cells. 1992 Biochem. Pharmacol. pmid:1417983
Maynard PM et al. Effect of glutathione depletion on tissue and plasma prostacyclin and thromboxane in rats. 1992 Biochem. Pharmacol. pmid:1554377
Maellaro E et al. Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents. 1990 Biochem. Pharmacol. pmid:2337408
Hassan AS et al. Glutathione and bile acid synthesis. Effect of GSH content of HepG2 cells on the activity and mRNA levels of cholesterol 7 alpha-hydroxylase. 1992 Biochem. Pharmacol. pmid:1417970
Strachan GD et al. Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein. 2004 Biochemistry pmid:15379550
Kim JY et al. Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. 2001 Biochim. Biophys. Acta pmid:11406111
Gaubin Y et al. Implication of free radicals and glutathione in the mechanism of cadmium-induced expression of stress proteins in the A549 human lung cell-line. 2000 Biochim. Biophys. Acta pmid:10634927
Sweiry JH et al. Acute oxidative stress modulates secretion and repetitive Ca2+ spiking in rat exocrine pancreas. 1999 Biochim. Biophys. Acta pmid:10354511
Sato H et al. Induction of cystine transport via system x-c and maintenance of intracellular glutathione levels in pancreatic acinar and islet cell lines. 1998 Biochim. Biophys. Acta pmid:9804903
Nishida K et al. Conversion of gamma-glutamylcysteinylethyl ester to glutathione in rat hepatocytes. 1996 Biochim. Biophys. Acta pmid:8781549
Bottje W et al. Indomethacin attenuation of hepatic perfusion and plasma 6-ketoPGF1 alpha elevations following glutathione depletion in rabbits. 1991 Biochim. Biophys. Acta pmid:1991131
Iantomasi T et al. Increased glutathione synthesis associated with platelet-derived growth factor stimulation of NIH3T3 fibroblasts. 1999 Biochim. Biophys. Acta pmid:10590319
Kodiha M et al. Oxidative stress mislocalizes and retains transport factor importin-alpha and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes. 2008 Biochim. Biophys. Acta pmid:18068677
Vairetti M et al. Apoptosis vs. necrosis: glutathione-mediated cell death during rewarming of rat hepatocytes. 2005 Biochim. Biophys. Acta pmid:15949704
Tosaki T et al. Enhancement of acetyl-CoA: 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity by hydrogen peroxide. 2007 Biol. Pharm. Bull. pmid:17268064
Yamamoto F et al. Decreased tissue accumulation of 6-deoxy-6-[18F]fluoro-L-ascorbic acid in glutathione-deficient rats induced by administration of diethyl maleate. 2005 Biol. Pharm. Bull. pmid:16204951
Pallis M et al. Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status. 2001 Blood pmid:11435310

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