Monoethyl maleate

Monoethyl maleate is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1650 references associated with Monoethyl maleate in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Monoethyl maleate

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Monoethyl maleate

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Stomach Ulcer D013276 75 associated lipids
Total 3

All references with Monoethyl maleate

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Authors Title Published Journal PubMed Link
Altomare E et al. Acute ethanol administration induces oxidative changes in rat pancreatic tissue. 1996 Gut pmid:8707122
Jezequel AM et al. Early structural and functional changes in liver of rats treated with a single dose of valproic acid. Hepatology pmid:6437962
Srivastava RC et al. Distribution of nickel in diethylmaleate (DEM) pre-treated rats: protective role of glutathione and histidine. 1988 Ind Health pmid:3182304
Wang F et al. Redox imbalance differentially inhibits lipopolysaccharide-induced macrophage activation in the mouse liver. 1999 Infect. Immun. pmid:10496923
Esposito F et al. Regulation of p21waf1/cip1 expression by intracellular redox conditions. 2001 IUBMB Life pmid:11795596
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Madden JA et al. Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung. 2012 J. Appl. Physiol. pmid:22074719
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Horton ND et al. Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung adenocarcinoma (A549) cells. 1999 J. Biol. Chem. pmid:10092592
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Zhao XJ et al. Function and expression of flavohemoglobin in Saccharomyces cerevisiae. Evidence for a role in the oxidative stress response. 1996 J. Biol. Chem. pmid:8810268
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Buckley BJ et al. Regulation of endothelial cell prostaglandin synthesis by glutathione. 1991 J. Biol. Chem. pmid:1885596
Olson CE et al. Modulating effect of thiol-disulfide status on [14C]aminopyrine accumulation in the isolated parietal cell. 1985 J. Biol. Chem. pmid:4008488
Bannai S Induction of cystine and glutamate transport activity in human fibroblasts by diethyl maleate and other electrophilic agents. 1984 J. Biol. Chem. pmid:6142042
Katsuoka F et al. Nrf2 transcriptionally activates the mafG gene through an antioxidant response element. 2005 J. Biol. Chem. pmid:15574414
Kalo E et al. Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species. 2012 J. Cell. Sci. pmid:22899716
Harlan JM et al. Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide. 1984 J. Clin. Invest. pmid:6707200
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Speck RF et al. Prednisolone stimulates hepatic glutathione synthesis in mice. Protection by prednisolone against acetaminophen hepatotoxicity in vivo. 1993 J. Hepatol. pmid:8340611
Nathens AB et al. Thiol-mediated regulation of ICAM-1 expression in endotoxin-induced acute lung injury. 1998 J. Immunol. pmid:9510200
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Williamson RT et al. Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems. 2000 J. Nat. Prod. pmid:10869227
Chen CJ and Liao SL Zinc toxicity on neonatal cortical neurons: involvement of glutathione chelation. 2003 J. Neurochem. pmid:12675920
Kang YS et al. Regulation of taurine transport at the blood-brain barrier by tumor necrosis factor-alpha, taurine and hypertonicity. 2002 J. Neurochem. pmid:12437590
O'Shea E et al. Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia. 2002 J. Neurochem. pmid:12065628
Rabinovic AD and Hastings TG Role of endogenous glutathione in the oxidation of dopamine. 1998 J. Neurochem. pmid:9798932
Liao SL et al. Diethylmaleate and iodoacetate in combination caused profound cell death in astrocytes. 2013 J. Neurochem. pmid:23647195
Wadey AL et al. Mitochondrial glutathione uptake: characterization in isolated brain mitochondria and astrocytes in culture. 2009 J. Neurochem. pmid:19393015
Romero JM and Bizzozero OA Intracellular glutathione mediates the denitrosylation of protein nitrosothiols in the rat spinal cord. 2009 J. Neurosci. Res. pmid:18831065
Sasaki T et al. Distribution of glutathione and technetium-99m-meso-HMPAO in normal and diethyl maleate-treated mouse brain mitochondria. 1998 J. Nucl. Med. pmid:9867165
Sasaki T and Senda M Technetium-99m-meso-HMPAO as a potential agent to image cerebral glutathione content. 1997 J. Nucl. Med. pmid:9225804
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Hosoya K et al. Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. 2002 J. Pharmacol. Exp. Ther. pmid:12065721
Takeuchi K et al. Role of sulfhydryls in mucosal injury caused by ethanol: relation to microvascular permeability, gastric motility and cytoprotection. 1989 J. Pharmacol. Exp. Ther. pmid:2918483
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Belinsky SA et al. Mechanism of hepatotoxicity in periportal regions of the liver lobule due to allyl alcohol: studies on thiols and energy status. 1986 J. Pharmacol. Exp. Ther. pmid:3746662
Den Boer PJ et al. Effect of glutathione depletion on the cytotoxicity of xenobiotics and induction of single-strand DNA breaks by ionizing radiation in isolated hamster round spermatids. 1990 J. Reprod. Fertil. pmid:2313642
Den Boer PJ et al. Glutathione metabolism in cultured Sertoli cells and spermatogenic cells from hamsters. 1989 J. Reprod. Fertil. pmid:2621712
Nathens AB et al. The glutathione depleting agent diethylmaleate prolongs renal allograft survival. 1998 J. Surg. Res. pmid:9698537
Nakano S and Gemba M Potentiation of cisplatin-induced lipid peroxidation in kidney cortical slices by glutathione depletion. 1989 Jpn. J. Pharmacol. pmid:2770062

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