Damps T et al. |
The effect of wool hydrolysates on squamous cell carcinoma cells in vitro. Possible implications for cancer treatment. |
2017 |
PLoS ONE |
pmid:28859143
|
Asche CV et al. |
Evaluation of Resource Utilization and Treatment Patterns in Patients with Actinic Keratosis in the United States. |
2016 Mar-Apr |
Value Health |
pmid:27021759
|
Zane C et al. |
A Randomized Split-Face Clinical Trial of Photodynamic Therapy with Methyl Aminolevulinate versus Ingenol Mebutate Gel for the Treatment of Multiple Actinic Keratoses of the Face and Scalp. |
2016 |
Dermatology (Basel) |
pmid:27578305
|
Mühlstädt M |
Ingenol Mebutate vs. Daylight Photodynamic Therapy in a Kidney Transplant Recipient. |
2016 |
Dermatology (Basel) |
pmid:27513345
|
Erlendsson AM et al. |
Repeated Treatments with Ingenol Mebutate Prevents Progression of UV-Induced Photodamage in Hairless Mice. |
2016 |
PLoS ONE |
pmid:27636884
|
Emmert S et al. |
Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate. |
2016 |
PLoS ONE |
pmid:27612149
|
Liu M et al. |
Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate. |
2016 |
Int J Mol Sci |
pmid:27548156
|
Mohanna MT and Hofbauer GF |
Bowenoid Actinic Keratosis and Bowen's Disease Treated Successfully with Ingenol Mebutate. |
2016 |
Dermatology (Basel) |
pmid:27513957
|
Mainetti C et al. |
Successful Treatment of Relapsing Bowen's Disease with Ingenol Mebutate: The Use of Dermoscopy to Monitor the Therapeutic Response. |
2016 |
Dermatology (Basel) |
pmid:27513936
|
Gaide O et al. |
Ingenol Mebutate 500 μg for Treatment of the Scalp in Refractory Field Cancerization. |
2016 |
Dermatology (Basel) |
pmid:27513862
|
Gaide O and Cattin V |
Ingenol Mebutate 500 µg on the Cheekbones with Concomitant Conjunctivitis. |
2016 |
Dermatology (Basel) |
pmid:27513756
|
Tzika E et al. |
Ingenol Mebutate for Recalcitrant Chronic Actinic Cheilitis. |
2016 |
Dermatology (Basel) |
pmid:27513668
|
Stieger M and Hunger RE |
Ingenol Mebutate Treatment in a Patient with Gorlin Syndrome. |
2016 |
Dermatology (Basel) |
pmid:27513585
|
Gadaldi K et al. |
Ingenol Mebutate for Lentigo Maligna: A Case Report. |
2016 |
Dermatology (Basel) |
pmid:27513527
|
Alkhalaf A and Hofbauer GF |
Ingenol Mebutate 150 mg as Physician-Directed Treatment of Bowen's Disease Under Occlusion. |
2016 |
Dermatology (Basel) |
pmid:27512986
|
Le TT et al. |
IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate. |
2016 |
PLoS ONE |
pmid:27100888
|
Stockfleth E et al. |
New Topical Treatment Options for Actinic Keratosis: A Systematic Review. |
2016 |
Acta Derm. Venereol. |
pmid:26068001
|
Bhandari PR and Pai VV |
Could ingenol mebutate be useful in managing nonmelanoma skin cancers? |
2015 Apr-Jun |
Indian J Cancer |
pmid:26853424
|
De Felice B et al. |
Ingenol mebutate treatment in keloids. |
2015 |
BMC Res Notes |
pmid:26391582
|
Pellacani G et al. |
A randomized trial comparing simultaneous vs. sequential field treatment of actinic keratosis with ingenol mebutate on two separate areas of the head and body. |
2015 |
J Eur Acad Dermatol Venereol |
pmid:26300464
|
Jiang G et al. |
Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation. |
2015 |
PLoS Pathog. |
pmid:26225771
|
Freiberger SN et al. |
Ingenol Mebutate Signals via PKC/MEK/ERK in Keratinocytes and Induces Interleukin Decoy Receptors IL1R2 and IL13RA2. |
2015 |
Mol. Cancer Ther. |
pmid:26116359
|
Soini EJ et al. |
Cost-utility of first-line actinic keratosis treatments in Finland. |
2015 |
Adv Ther |
pmid:26006101
|
Cantisani C et al. |
Evaluation of Ingenol mebutate efficacy for the treatment of actinic keratosis with Antera 3D camera. |
2015 |
Eur Rev Med Pharmacol Sci |
pmid:25635981
|
Edwards SK et al. |
N-benzyladriamycin-14-valerate (AD 198) exhibits potent anti-tumor activity on TRAF3-deficient mouse B lymphoma and human multiple myeloma. |
2013 |
BMC Cancer |
pmid:24131623
|
Song X et al. |
RasGRPs are targets of the anti-cancer agent ingenol-3-angelate. |
2013 |
PLoS ONE |
pmid:23991094
|
Cozzi SJ et al. |
Effective treatment of squamous cell carcinomas with ingenol mebutate gel in immunologically intact SKH1 mice. |
2013 |
Arch. Dermatol. Res. |
pmid:22871992
|
Liang X et al. |
Syntheses, biological evaluation and SAR of ingenol mebutate analogues for treatment of actinic keratosis and non-melanoma skin cancer. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23993332
|
Doan HQ et al. |
Ingenol mebutate: potential for further development of cancer immunotherapy. |
2012 |
J Drugs Dermatol |
pmid:23134979
|
Lebwohl M et al. |
Ingenol mebutate gel for actinic keratosis. |
2012 |
N. Engl. J. Med. |
pmid:22417254
|
Fallen RS and Gooderham M |
Ingenol mebutate: an introduction. |
2012 |
Skin Therapy Lett. |
pmid:22358305
|
Cozzi SJ et al. |
Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches. |
2012 |
J. Invest. Dermatol. |
pmid:22189786
|
Lee WY et al. |
Novel antileukemic compound ingenol 3-angelate inhibits T cell apoptosis by activating protein kinase Ctheta. |
2010 |
J. Biol. Chem. |
pmid:20472553
|
Li L et al. |
The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. |
2010 |
Cancer Res. |
pmid:20460505
|
Ghoul A et al. |
Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. |
2009 |
Cancer Res. |
pmid:19417139
|
Benhadji KA et al. |
Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. |
2008 |
Br. J. Cancer |
pmid:19034280
|
Serova M et al. |
Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18413805
|
Challacombe JM et al. |
Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate. |
2006 |
J. Immunol. |
pmid:17114487
|
Cozzi SJ et al. |
Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway. |
2006 |
Cancer Res. |
pmid:17047072
|
Hampson P et al. |
PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. |
2005 |
Blood |
pmid:15845901
|
Gillespie SK et al. |
Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. |
2004 |
Mol. Cancer Ther. |
pmid:15634659
|
Ogbourne SM et al. |
Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. |
2004 |
Cancer Res. |
pmid:15087400
|
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pmid:22538622
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pmid:22055282
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pmid:21325841
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pmid:20546215
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pmid:19922462
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pmid:17115221
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