Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Placental Insufficiency D010927 6 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Cleft Lip D002971 8 associated lipids
Myocardial Stunning D017682 10 associated lipids
Ketosis D007662 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypothyroidism D007037 32 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Sleboda J et al. Short-term regulation of carnitine palmitoyltransferase I in cultured rat hepatocytes: spontaneous inactivation and reactivation by fatty acids. 1999 Biochim. Biophys. Acta pmid:9989283
Pande SV et al. Freeze-thawing causes masking of membrane-bound outer carnitine palmitoyltransferase activity: implications for studies on carnitine palmitoyltransferases deficiency. 1990 Biochim. Biophys. Acta pmid:2344445
Morash AJ et al. Intertissue regulation of carnitine palmitoyltransferase I (CPTI): mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss). 2008 Biochim. Biophys. Acta pmid:18359285
Skrede S and Bremer J Acylcarnitine formation and fatty acid oxidation in hepatocytes from rats treated with tetradecylthioacetic acid (a 3-thia fatty acid). 1993 Biochim. Biophys. Acta pmid:8466948
Gambert S et al. Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. 2005 Biochim. Biophys. Acta pmid:16153888
Bolton P and Harwood JL Some characteristics of soluble fatty acid synthesis in germinating pea seeds. 1977 Biochim. Biophys. Acta pmid:20971
Veerkamp JH and Van Moerkerk HT The effect of malonyl-CoA on fatty acid oxidation in rat muscle and liver mitochondria. 1982 Biochim. Biophys. Acta pmid:7066363
Lund H and Woldegiorgis G Carnitine palmitoyltransferase: separation of enzyme activity and malonyl-CoA binding in rat liver mitochondria. 1986 Biochim. Biophys. Acta pmid:3756194
Bergseth S et al. Carnitine palmitoyltransferase: activation and inactivation in liver mitochondria from fed, fasted, hypo- and hyperthyroid rats. 1986 Biochim. Biophys. Acta pmid:3707984
Lund H et al. Effects of thyroid state and fasting on the concentrations of CoA and malonyl-CoA in rat liver. 1986 Biochim. Biophys. Acta pmid:3707992
Bremer J The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. 1981 Biochim. Biophys. Acta pmid:7295757
Deana R et al. Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver. 1981 Biochim. Biophys. Acta pmid:6946836
Kerner J and Hoppel C Fatty acid import into mitochondria. 2000 Biochim. Biophys. Acta pmid:10856709
Kugi M et al. Characterization of fatty acid elongation system in porcine neutrophil microsomes. 1990 Biochim. Biophys. Acta pmid:2310764
Cassagne C et al. Fatty acid biosynthesis in the peripheral nervous system of normal and Trembler mice. 1986 Biochim. Biophys. Acta pmid:3947661
Sire O et al. Preventive effect of clofibrate on carnitine palmitoyltransferase I inhibition and mitochondrial membrane phospholipid depletion induced by galactosamine. 1986 Biochim. Biophys. Acta pmid:3947665
Demirkapi N et al. Evidence against cytochrome b5 involvement in liver microsomal fatty acid elongation. 1991 Biochim. Biophys. Acta pmid:2009301
Vandhana S et al. Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. 2013 Biochim. Biophys. Acta pmid:23816424
Katsurada A et al. Effects of dietary nutrients on substrate and effector levels of lipogenic enzymes, and lipogenesis from tritiated water in rat liver. 1986 Biochim. Biophys. Acta pmid:2875738
Giompres P and Packter NM Purification and properties of the polymeric fatty acid synthetase from a filamentous fungus. 1978 Biochim. Biophys. Acta pmid:350287
Bhatia H et al. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. 2014 Biochim. Biophys. Acta pmid:24560669
Bieber LL and Wagner M Effect of pH and acyl-CoA chain length on the conversion of heart mitochondrial CPT-I/CPTo to a high affinity, malonyl-CoA-inhibited state. 1996 Biochim. Biophys. Acta pmid:8765129
Christophersen BO et al. Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells. 1982 Biochim. Biophys. Acta pmid:6812639
Rous S Possible contribution of [2-3H]malate and [2, 3-3h]succinate tritium to the same tritiated NADPH pool for participation in fatty acid synthesis. 1978 Biochimie pmid:27240
McGarry JD et al. New insights into the mitochondrial carnitine palmitoyltransferase enzyme system. 1991 Biochimie pmid:2031961
López M et al. Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. 2007 Bioessays pmid:17295284
Adams SH et al. Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat. 1998 Biol. Reprod. pmid:9828184
Valsangkar D and Downs SM A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. 2013 Biol. Reprod. pmid:23863407
De Spiegeleer BM et al. High performance liquid chromatography stability study of malonyl-coenzyme A, using statistical experimental designs. 1989 Biomed. Chromatogr. pmid:2804428
Gilibili RR et al. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues. 2011 Biomed. Chromatogr. pmid:21381064
Bengtsson C et al. Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. 2011 Bioorg. Med. Chem. pmid:21515056
Abe T et al. Structure function analysis of benzalacetone synthase from Rheum palmatum. 2007 Bioorg. Med. Chem. Lett. pmid:17383877
Gao BW et al. Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis. 2015 Bioorg. Med. Chem. Lett. pmid:25677661
Wallace DM et al. Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors. 2007 Bioorg. Med. Chem. Lett. pmid:17234415
Jia Y and Zhong JJ Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum. 2011 Bioresour. Technol. pmid:21907573
Wu J et al. Efficient biosynthesis of (2S)-pinocembrin from d-glucose by integrating engineering central metabolic pathways with a pH-shift control strategy. 2016 Bioresour. Technol. pmid:27450982
Chohnan S et al. Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses. 1998 Biosci. Biotechnol. Biochem. pmid:9692193
Hayashi O and Satoh K Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. 2008 Biosci. Biotechnol. Biochem. pmid:18323644
Kajikawa M et al. Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L. 2003 Biosci. Biotechnol. Biochem. pmid:12723610
Hayashi O and Satoh K Determination of acetyl-CoA and malonyl-CoA in germinating rice seeds using the LC-MS/MS technique. 2006 Biosci. Biotechnol. Biochem. pmid:17090944
Sugden MC et al. Lipogenesis in response to an oral glucose load in fed and starved rats. 1981 Biosci. Rep. pmid:7295901
Maharjan S et al. Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides. 2010 Biotechnol. Lett. pmid:19838628
Zhang X et al. Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase. 2012 Jan-Feb Biotechnol. Prog. pmid:22038854
Celato A et al. A new case of malonic aciduria with a presymptomatic diagnosis and an early treatment. 2013 Brain Dev. pmid:23177061
Salles J et al. Fatty acid synthase expression during peripheral nervous system myelination. 2002 Brain Res. Mol. Brain Res. pmid:12007831
Onay-Besikci A and Sambandam N Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply. 2006 Can. J. Physiol. Pharmacol. pmid:17218986
Li JN et al. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. 2001 Cancer Res. pmid:11245456
Brusselmans K et al. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. 2005 Cancer Res. pmid:16061653
Pizer ES et al. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. 2000 Cancer Res. pmid:10667561
Maurer I and Zierz S Carnitine palmitoyltransferase in patients with cardiac ischemia due to atherosclerotic coronary artery disease and in patients with idiopathic dilated cardiomyopathy. 1997 May-Jun Cardiology pmid:9129847
Kudej RK et al. Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. 2011 Cardiovasc. Res. pmid:21835931
Folmes CD and Lopaschuk GD Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. 2007 Cardiovasc. Res. pmid:17126822
Ussher JR and Lopaschuk GD The malonyl CoA axis as a potential target for treating ischaemic heart disease. 2008 Cardiovasc. Res. pmid:18499682
Ussher JR et al. Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. 2012 Cardiovasc. Res. pmid:22436846
Zhabyeyev P et al. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. 2013 Cardiovasc. Res. pmid:23257023
Mercier R et al. Excess membrane synthesis drives a primitive mode of cell proliferation. 2013 Cell pmid:23452849
Unger RH The hyperleptinemia of obesity-regulator of caloric surpluses. 2004 Cell pmid:15084251
Giordano A et al. tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. 2005 Cell Death Differ. pmid:15846373
Dean JT et al. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. 2009 Cell Metab. pmid:19490907
Kelley DE Pulling in more fat. 2005 Cell Metab. pmid:16271525
Neschen S et al. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. 2005 Cell Metab. pmid:16054099
López M et al. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. 2008 Cell Metab. pmid:18460330
Zammit VA and Arduini A The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. 2008 Cell Metab. pmid:18762014
Zhang S and Kim KH Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. 1998 Cell. Signal. pmid:9502115
Awakawa T et al. Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. 2009 Chem. Biol. pmid:19549600
Zhou P et al. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. 1999 Chem. Biol. pmid:10421763
Matharu AL et al. MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor. 1998 Chem. Biol. pmid:9862793
Jensen K et al. Polyketide proofreading by an acyltransferase-like enzyme. 2012 Chem. Biol. pmid:22444588
Kage H et al. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. 2013 Chem. Biol. pmid:23790487
Ellis JM and Wolfgang MJ A genetically encoded metabolite sensor for malonyl-CoA. 2012 Chem. Biol. pmid:23102226
Hitchman TS et al. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. 1998 Chem. Biol. pmid:9479478
Hamed RB et al. Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. 2010 Chem. Commun. (Camb.) pmid:20162132
Tosin M et al. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. 2009 Chembiochem pmid:19507202
Musiol EM et al. The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. 2013 Chembiochem pmid:23828654
Awakawa T et al. 4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. 2013 Chembiochem pmid:23609937
Kantor PF et al. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. 2000 Circ. Res. pmid:10720420
Zordoky BN et al. AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation. 2014 Circ. Res. pmid:25001074
Lewandowski ED et al. Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. 2013 Circ. Res. pmid:22982985
Kolwicz SC et al. Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. 2012 Circ. Res. pmid:22730442
Dyck JR et al. Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. 2004 Circ. Res. pmid:15105298
Dagher Z et al. Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. 2001 Circ. Res. pmid:11420304
Goodman SI et al. Methylmalonic/beta-hydroxy-n-valeric aciduria due to methylmalonyl-CoA mutase deficiency. 1978 Clin. Chim. Acta pmid:28187
Wen J and Kerr RG Purification and characterization of the fatty acid synthase from Bugula neritina. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11250539
Gutières S et al. Cloning and tissue distribution of a carnitine palmitoyltransferase I gene in rainbow trout (Oncorhynchus mykiss). 2003 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:12781981
Lavarías S et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). 2009 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:19171199
McGrath RP Unusual case of metabolic acidosis. 1989 Crit. Care Med. pmid:2909311
Schujman GE et al. FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. 2003 Dev. Cell pmid:12737802
Roche E et al. Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. 1998 Diabetes pmid:9648832
Foster DW Banting lecture 1984. From glycogen to ketones--and back. 1984 Diabetes pmid:6094292
Chen S et al. More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling. 1994 Diabetes pmid:8013751
Prentki M and Corkey BE Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? 1996 Diabetes pmid:8593930
Komatsu M and Sharp GW Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+. 1998 Diabetes pmid:9519739
Beynen AC et al. Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis. 1979 Diabetes pmid:467808
Roduit R et al. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. 2004 Diabetes pmid:15047616
Brun T et al. Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling. 1996 Diabetes pmid:8549864
Matschinsky FM Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. 1996 Diabetes pmid:8549869
Herrero L et al. Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion. 2005 Diabetes pmid:15677504
Nolan CJ et al. Fatty acid signaling in the beta-cell and insulin secretion. 2006 Diabetes pmid:17130640
Dean D et al. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. 2000 Diabetes pmid:10923628
Oakes ND et al. Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. 1997 Diabetes pmid:9392490