Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Liang JL et al. A novel process for obtaining pinosylvin using combinatorial bioengineering in Escherichia coli. 2016 World J. Microbiol. Biotechnol. pmid:27116968
Cheng R et al. Cloning and functional analysis of putative malonyl-CoA:acyl-carrier protein transacylase gene from the docosahexaenoic acid-producer Schizochytrium sp. TIO1101. 2013 World J. Microbiol. Biotechnol. pmid:23292648
McGarry JD Malonyl-CoA and satiety? Food for thought. 2000 Trends Endocrinol. Metab. pmid:11091115
Mandrup S et al. In memoriam: M. Daniel Lane, 1930-2014. 2014 Trends Endocrinol. Metab. pmid:25084731
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Shen B and Hutchinson CR Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A. 1993 Science pmid:8248801
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Ma SM et al. Complete reconstitution of a highly reducing iterative polyketide synthase. 2009 Science pmid:19900898
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Marsden AF et al. Stereospecific acyl transfers on the erythromycin-producing polyketide synthase. 1994 Science pmid:8278811
Ruderman N and Flier JS Cell biology. Chewing the fat--ACC and energy balance. 2001 Science pmid:11286278
Moré MI et al. Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. 1996 Science pmid:8658141
Neels JG and Olefsky JM Cell signaling. A new way to burn fat. 2006 Science pmid:16794069
Loftus TM et al. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. 2000 Science pmid:10875926
Gura T Obesity. Enzyme blocker prompts mice to shed weight. 2000 Science pmid:10917820
Wu J et al. Enhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli. 2015 Sci Rep pmid:26323217
Albaugh VL et al. Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents. 2012 Schizophr Bull pmid:20494946
Dawe JH et al. A template search reveals mechanistic similarities and differences in beta-ketoacyl synthases (KAS) and related enzymes. 2003 Proteins pmid:12866053
Wang YY et al. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. 2015 Protein Pept. Lett. pmid:25267255
Cheng D et al. Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes. 2007 Protein Expr. Purif. pmid:16854592
Cha SH et al. Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18971329
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Thupari JN et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12060712
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Abu-Elheiga L et al. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16103361
Oh W et al. Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15677334
Cheng YQ et al. Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12598647
Tomas E et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12456889
Cha SH et al. Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:17030788
Wolfgang MJ et al. The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16651524
Mao J et al. Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16717184
Murthy MS and Pande SV Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3540964
Suo Z et al. Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:11106385
Cha SH et al. Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16203972
Hu Z et al. Hypothalamic malonyl-CoA as a mediator of feeding behavior. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:14532332
Xu P et al. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25049420
Gao S et al. Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21593415
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Saez G et al. Gene expression and protein content in relation to intramuscular fat content in Muscovy and Pekin ducks. 2009 Poult. Sci. pmid:19834090
Koyuncu E et al. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. 2013 PLoS Pathog. pmid:23696731
Albanesi D et al. Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. 2013 PLoS Pathog. pmid:23300457
Serviddio G et al. Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet. 2011 PLoS ONE pmid:21909411
ElAzzouny MA et al. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. 2015 PLoS ONE pmid:26107620
Liu C et al. Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. 2013 PLoS ONE pmid:24073271
Moore RG et al. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. 2012 PLoS ONE pmid:22509304
Suh MC et al. What limits production of unusual monoenoic fatty acids in transgenic plants? 2002 Planta pmid:12172841
Kim DH et al. Molecular characterization of flavonoid malonyltransferase from Oryza sativa. 2009 Nov-Dec Plant Physiol. Biochem. pmid:19733090
Metz JG et al. Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. 2009 Plant Physiol. Biochem. pmid:19272783
Raharjo TJ et al. Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa. 2004 Plant Physiol. Biochem. pmid:15120113
Focke M et al. Fatty acid biosynthesis in mitochondria of grasses: malonyl-coenzyme A is generated by a mitochondrial-localized acetyl-coenzyme A carboxylase. 2003 Plant Physiol. pmid:12972648
Hammerbacher A et al. Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection. 2011 Plant Physiol. pmid:21865488
Levitan O et al. An RNA interference knock-down of nitrate reductase enhances lipid biosynthesis in the diatom Phaeodactylum tricornutum. 2015 Plant J. pmid:26473332
Bertoni G A key step in phlorotannin biosynthesis revealed. 2013 Plant Cell pmid:23995082
Falk KL et al. Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa. 2004 Phytochemistry pmid:15110687
Eckermann C et al. Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. 2003 Phytochemistry pmid:14568070
Morash AJ and McClelland GB Regulation of carnitine palmitoyltransferase (CPT) I during fasting in rainbow trout (Oncorhynchus mykiss) promotes increased mitochondrial fatty acid oxidation. 2011 Nov-Dec Physiol. Biochem. Zool. pmid:22030855
Gao S et al. Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. 2013 Physiol. Behav. pmid:23680429
Gao S et al. Hypothalamic malonyl-CoA and the control of food intake. 2013 Physiol. Behav. pmid:23988346
Cahová M et al. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. 2007 Physiol Res pmid:16497094
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Hamdan M et al. Inhibition of mitochondrial carnitine palmitoyltransferase-1 by a trimetazidine derivative, S-15176. 2001 Pharmacol. Res. pmid:11516258
Prada CE et al. Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy. 2012 Pediatrics pmid:22778304
Reindl BA et al. Sani-cloth wipe mimics rare enzyme deficiency malonic aciduria on newborn screen. 2012 Pediatrics pmid:23071203
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Loubière C et al. Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells. 2015 Oncotarget pmid:26002551
Celik A et al. Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia. 2009 Oncol. Rep. pmid:19288015
Fritz V et al. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. 2013 Oncogene pmid:23208508
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Cheng L et al. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. 2004 Nat. Med. pmid:15475963
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Schujman GE et al. A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism. 2008 Mol. Microbiol. pmid:18384517
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