Malonyl-coa

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Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Zhou L et al. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18083904
Sharma V et al. Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18203848
King KL et al. Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15821035
Stanley WC et al. beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12969881
Onay-Besikci A et al. Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12388233
Poirier M et al. Probing the link between citrate and malonyl-CoA in perfused rat hearts. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:12234788
Goodwin GW and Taegtmeyer H Improved energy homeostasis of the heart in the metabolic state of exercise. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11009433
Chandler MP et al. Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:15191896
Lin X et al. Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid {beta}-oxidation in liver of neonatal swine. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20237302
Morash AJ et al. Genome duplication events have led to a diversification in the CPT I gene family in fish. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20519364
Thyfault JP et al. Metabolic profiling of muscle contraction in lean compared with obese rodents. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20504904
Richards JG et al. Lipid oxidation fuels recovery from exhaustive exercise in white muscle of rainbow trout. 2002 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11742827
Murase T et al. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. 2006 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:16410398
Lane RH et al. Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats. 2001 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11124150
Gao S et al. Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21508288
Koves TR et al. Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. 2005 Am. J. Physiol., Cell Physiol. pmid:15647392
Onorato JM et al. Liquid-liquid extraction coupled with LC/MS/MS for monitoring of malonyl-CoA in rat brain tissue. 2010 Anal Bioanal Chem pmid:20549491
Minkler PE et al. Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. 2008 Anal. Biochem. pmid:18355435
Reszko AE et al. Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. 2001 Anal. Biochem. pmid:11673897
Wang X et al. Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. 2007 Anal. Biochem. pmid:17316539
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Minkler PE et al. Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry. 2006 Anal. Biochem. pmid:16545769
Kim YS and Bang SK Assays for malonyl-coenzyme A synthase. 1988 Anal. Biochem. pmid:3389517
Minkler PE et al. Isolation and identification of two isomeric forms of malonyl-coenzyme A in commercial malonyl-coenzyme A. 2004 Anal. Biochem. pmid:15113698
Alves J et al. Cloning, expression, and enzymatic activity of Acinetobacter baumannii and Klebsiella pneumoniae acetyl-coenzyme A carboxylases. 2011 Anal. Biochem. pmid:21704013
Rutkoski A and Jaworski JG An improved synthesis of malonyl-coenzyme A. 1978 Anal. Biochem. pmid:9762122
Zierz S and Schmitt U Inhibition of carnitine palmitoyltransferase by malonyl-CoA in human muscle is influenced by anesthesia. 1989 Anesthesiology pmid:2913880
Spiteller D et al. A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue. 2005 Angew. Chem. Int. Ed. Engl. pmid:16208728
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Foster DW The role of the carnitine system in human metabolism. 2004 Ann. N. Y. Acad. Sci. pmid:15590999
Ukropec J et al. An increase in peroxisomal fatty acid oxidation is not sufficient to prevent tissue lipid accumulation in hHTg rats. 2002 Ann. N. Y. Acad. Sci. pmid:12079837
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Dowell P et al. Monitoring energy balance: metabolites of fatty acid synthesis as hypothalamic sensors. 2005 Annu. Rev. Biochem. pmid:15952896
Wolfgang MJ and Lane MD Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system. 2006 Annu. Rev. Nutr. pmid:16704352
Saggerson D Malonyl-CoA, a key signaling molecule in mammalian cells. 2008 Annu. Rev. Nutr. pmid:18598135
Hunaiti AA and Kolattukudy PE Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus. 1984 Antimicrob. Agents Chemother. pmid:6143534
Fowler ZL et al. Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. 2009 Appl. Environ. Microbiol. pmid:19633125
Rodríguez E et al. Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). 2001 Appl. Environ. Microbiol. pmid:11526020
Leonard E et al. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. 2007 Appl. Environ. Microbiol. pmid:17468269
Karunakaran R et al. Malonate catabolism does not drive N2 fixation in legume nodules. 2013 Appl. Environ. Microbiol. pmid:23666330
Wu J et al. Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2S)-Naringenin Production from l-Tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:25239896
Zhu S et al. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:24610848
Chohnan S et al. Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. 1997 Appl. Environ. Microbiol. pmid:9023936
Miyahisa I et al. Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. 2005 Appl. Microbiol. Biotechnol. pmid:15770480
Rodriguez E et al. Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae. 2004 Appl. Microbiol. Biotechnol. pmid:15179529
Rao G et al. Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. 2013 Appl. Microbiol. Biotechnol. pmid:23358999
Murad S and Kishimoto Y Chain elongation of fatty acid in brain: a comparison of mitochondrial and microsomal enzyme activities. 1978 Arch. Biochem. Biophys. pmid:626498
Buckner JS et al. Synthesis of multimethyl-branched fatty acids by avian and mammalian fatty acid synthetase and its regulation by malonyl-CoA decarboxylase in the uropygial gland. 1978 Arch. Biochem. Biophys. pmid:629531
Ludwig SA and Sprecher H Substrate specificity studies on the malonyl-CoA-dependent chain elongation of all-cis polyunsaturated fatty acids by rat liver microsomes. 1979 Arch. Biochem. Biophys. pmid:543721
Cassagne C and Lessire R Biosynthesis of saturated very long chain fatty acids by purified membrane fractions from leek epidermal cells. 1978 Arch. Biochem. Biophys. pmid:736558
Rock CO et al. Coupling of the biosynthesis of fatty acids and fatty alcohols. 1978 Arch. Biochem. Biophys. pmid:24423
Hunter SC and Ohlrogge JB Regulation of spinach chloroplast acetyl-CoA carboxylase. 1998 Arch. Biochem. Biophys. pmid:9808758
Kim YS et al. Malonyl-CoA decarboxylase from Mycobacterium tuberculosis and Pseudomonas fluorescens. 1979 Arch. Biochem. Biophys. pmid:114118
Kim YS and Kolattukudy PE Purification and properties of malonyl-CoA decarboxylase from rat liver mitochondria and its immunological comparison with the enzymes from rat brain, heart, and mammary gland. 1978 Arch. Biochem. Biophys. pmid:101148
Kim YS and Kolattukudy PE Malonyl-CoA decarboxylase from the uropygial gland of waterfowl: purification, properties, immunological comparison, and role in regulating the synthesis of multimethyl-branched fatty acids. 1978 Arch. Biochem. Biophys. pmid:102255
Ahmad PM and Ahmad F Effect of citrate on the different reactions catalyzed by rat mammary gland acetyl CoA carboxylase. 1983 Arch. Biochem. Biophys. pmid:6130749
Willard HF and Rosenberg LE Interactions of methylmalonyl CoA mutase from normal human fibroblasts with adenosylcobalamin and methylmalonyl CoA: evidence for non-equivalent active sites. 1980 Arch. Biochem. Biophys. pmid:6102452
McMillin JB et al. Kinetic properties of carnitine palmitoyltransferase I in cultured neonatal rat cardiac myocytes. 1994 Arch. Biochem. Biophys. pmid:7913595
Agrawal VP and Stumpf PK Characterization and solubilization of an acyl chain elongation system in microsomes of leek epidermal cells. 1985 Arch. Biochem. Biophys. pmid:4015095
Guzmán M et al. Effects of proglycosyn (LY177507) on fatty acid metabolism in rat hepatocytes. 1993 Arch. Biochem. Biophys. pmid:8102045
Kikuchi S et al. Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG. 1992 Arch. Biochem. Biophys. pmid:1586161
Woldegiorgis G et al. Restoration of malonyl-CoA sensitivity of soluble rat liver mitochondria carnitine palmitoyltransferase by reconstitution with a partially purified malonyl-CoA binding protein. 1992 Arch. Biochem. Biophys. pmid:1586164
Falk KL and Guerra DJ Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach. 1993 Arch. Biochem. Biophys. pmid:8384834
Oh-Hashi Y et al. Temperature- and growth-phase-dependent changes in membrane fatty acid compositions of Brevibacterium ammoniagenes. 1986 Arch. Biochem. Biophys. pmid:3729431
Lilly K et al. The medium-chain carnitine acyltransferase activity associated with rat liver microsomes is malonyl-CoA sensitive. 1990 Arch. Biochem. Biophys. pmid:2353818
Kurosaki F Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot. 1996 Arch. Biochem. Biophys. pmid:8638933
Juárez P et al. A microsomal fatty acid synthetase from the integument of Blattella germanica synthesizes methyl-branched fatty acids, precursors to hydrocarbon and contact sex pheromone. 1992 Arch. Biochem. Biophys. pmid:1536569
Horie S et al. Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity. 1989 Arch. Biochem. Biophys. pmid:2774583
Wang D et al. Acetyl coenzyme A carboxylase activity in neonatal rat cardiac myocytes in culture: citrate dependence and effects of hypoxia. 1996 Arch. Biochem. Biophys. pmid:8561504
Zhu H et al. Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I. 1997 Arch. Biochem. Biophys. pmid:9344464
Hinderer W and Seitz HU In vitro inhibition of carrot chalcone synthase by 3'-nucleotidase: the role of the 3'-phosphate group of malonyl-coenzyme A in flavonoid biosynthesis. 1986 Arch. Biochem. Biophys. pmid:3008651
Zhu H et al. Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding. 2003 Arch. Biochem. Biophys. pmid:12706342
Cook HW Chain elongation in the formation of polyunsaturated fatty acids by brain: some properties of the microsomal system. 1982 Arch. Biochem. Biophys. pmid:7092216
Yoshida S and Takeshita M Analysis of the condensation step in elongation of very-long-chain saturated and tetraenoic fatty acyl-CoAs in swine cerebral microsomes. 1987 Arch. Biochem. Biophys. pmid:3579295
Matern U et al. Two flavonoid-specific malonyltransferases from cell suspension cultures of Petroselinum hortense: partial purification and some properties of malonyl-coenzyme A: flavone/flavonol-7-O-glycoside malonyltransferase and malonyl-coenzyme A: flavonol-3-O-glucoside malonyltransferase. 1981 Arch. Biochem. Biophys. pmid:7259181
Kolattukudy PE et al. Synthesis of methyl-branched fatty acids from methylmalonyl-CoA by fatty acid synthase from both the liver and the harderian gland of the guinea pig. 1987 Arch. Biochem. Biophys. pmid:3592662
Ryan RO et al. Biosynthesis of myristate in an aphid: involvement of a specific acylthioesterase. 1982 Arch. Biochem. Biophys. pmid:7059180
Blomquist GJ et al. Incorporation of [2,3-13C]succinate into methyl-branched alkanes in a termite. 1980 Arch. Biochem. Biophys. pmid:7447468
Anderson GJ and Kolattukudy PE Fatty acid chain elongation by microsomal enzymes from the bovine meibomian gland. 1985 Arch. Biochem. Biophys. pmid:3918501
Kurosaki F Dissociation of dimeric 6-hydroxymellein synthase, a polyketide biosynthetic enzyme in carrot cell extracts, with loss of keto-reducing activity. 1995 Arch. Biochem. Biophys. pmid:7639527
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Laguna JC et al. Action of Ebselen on rat hepatic microsomal enzyme-catalyzed fatty acid chain elongation, desaturation, and drug biotransformation. 1989 Arch. Biochem. Biophys. pmid:2563645
Bedord CJ et al. alpha-linolenic acid biosynthesis in Cyanidium caldarium. 1978 Arch. Biochem. Biophys. pmid:414660
Velasco G et al. Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism. 1997 Arch. Biochem. Biophys. pmid:9016810
Kerner J et al. Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation. 2008 Arch. Physiol. Biochem. pmid:18629681
Patil PB et al. Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. 2007 Arch. Physiol. Biochem. pmid:17522981
Liu Y et al. Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. 2007 Assay Drug Dev Technol pmid:17477831
Weiss DR and Glickman JF Characterization of fatty acid synthase activity using scintillation proximity. 2003 Assay Drug Dev Technol pmid:15090142
Ussher JR and Lopaschuk GD Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. 2009 Basic Res. Cardiol. pmid:19242641
Nicot C et al. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. 2004 Biochem. Biophys. Res. Commun. pmid:15541339
Yoshida S et al. Stereospecific incorporation of hydrogens from NADPH in elongation of very long fatty acyl-CoA by swine cerebral microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6497886
Guzmán M and Geelen MJ Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol. 1988 Biochem. Biophys. Res. Commun. pmid:3401227
Cook GA et al. Feeding of lovastatin to rats increases the activity of the hepatic mitochondrial outer carnitine palmitoyltransferase. 1988 Biochem. Biophys. Res. Commun. pmid:3342059
Tokutake Y et al. Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. 2012 Biochem. Biophys. Res. Commun. pmid:22713453