Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Rutkoski A and Jaworski JG Fatty acid synthetase from chloroplasts of soybean cotyledons: ACP activation and CoA inhibition. 1978 Biochem. Biophys. Res. Commun. pmid:718691
Cha SH and Lane MD Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway. 2009 Biochem. Biophys. Res. Commun. pmid:19523445
Takeshita M et al. Decrease of palmitoyl-CoA elongation in platelets and leukocytes in the patient of hereditary methemoglobinemia associated with mental retardation. 1987 Biochem. Biophys. Res. Commun. pmid:3675585
White JS Significance of differential effects of glucose and fructose on brain food signaling is uncertain. 2009 Biochem. Biophys. Res. Commun. pmid:19785993
Kashfi K et al. Effects of cholesterol loading of mouse macrophages on carnitine palmitoyltransferase activity and sensitivity to inhibition by malonyl-CoA. 1991 Biochem. Biophys. Res. Commun. pmid:2059202
Thupari JN et al. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. 2001 Biochem. Biophys. Res. Commun. pmid:11444828
Eaton S et al. Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. 2001 Biochem. Biophys. Res. Commun. pmid:11444876
Kashfi K and Cook GA Malonyl-CoA inhibits proteolysis of carnitine palmitoyltransferase. 1991 Biochem. Biophys. Res. Commun. pmid:1859420
Oguro S et al. Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. 2004 Biochem. Biophys. Res. Commun. pmid:15530429
Nicot C et al. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. 2004 Biochem. Biophys. Res. Commun. pmid:15541339
Saito K et al. Differential hydrogen exchange during the fatty acid synthetase reaction: deuterium distribution of fatty acids synthesized from [2-2H2]malonyl-CoA. 1982 Biochem. Biophys. Res. Commun. pmid:6758778
Dai J et al. Leucine-764 near the extreme C-terminal end of carnitine palmitoyltransferase I is important for activity. 2003 Biochem. Biophys. Res. Commun. pmid:12565845
Yoshida S et al. Stereospecific incorporation of hydrogens from NADPH in elongation of very long fatty acyl-CoA by swine cerebral microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6497886
Saha AK et al. AMPK regulation of the growth of cultured human keratinocytes. 2006 Biochem. Biophys. Res. Commun. pmid:16949049
Guzmán M and Geelen MJ Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol. 1988 Biochem. Biophys. Res. Commun. pmid:3401227
Knudsen J and Grunnet I Primer specificity of mammalian mammary gland fatty acid synthetases. 1980 Biochem. Biophys. Res. Commun. pmid:7417345
Cook GA et al. Feeding of lovastatin to rats increases the activity of the hepatic mitochondrial outer carnitine palmitoyltransferase. 1988 Biochem. Biophys. Res. Commun. pmid:3342059
Guzmán M et al. Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA. 1987 Biochem. Biophys. Res. Commun. pmid:3426584
Suh DY et al. Evidence for catalytic cysteine-histidine dyad in chalcone synthase. 2000 Biochem. Biophys. Res. Commun. pmid:10973790
Tokutake Y et al. Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. 2012 Biochem. Biophys. Res. Commun. pmid:22713453
Iio W et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. 2012 Biochem. Biophys. Res. Commun. pmid:22503976
Peñas M and Benito M Regulation of carnitine palmitoyltransferase activity in the liver and brown adipose tissue in the newborn rat: effect of starvation and hypothermia. 1986 Biochem. Biophys. Res. Commun. pmid:3964261
Nagi MN et al. Evidence for two separate beta-ketoacyl CoA reductase components of the hepatic microsomal fatty acid chain elongation system in the rat. 1989 Biochem. Biophys. Res. Commun. pmid:2692567
Luthria DL et al. Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. 1997 Biochem. Biophys. Res. Commun. pmid:9144553
Tokutake Y et al. Coenzyme A and its thioester pools in fasted and fed rat tissues. 2010 Biochem. Biophys. Res. Commun. pmid:20933504
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Moir AM and Zammit VA Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume. 1995 Biochem. J. pmid:7848296
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Zammit VA The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. 1999 Biochem. J. pmid:10527927
Saggerson ED et al. Effects of thyroidectomy and starvation on the activity and properties of hepatic carnitine palmitoyltransferase. 1982 Biochem. J. pmid:7165724
Niot I et al. Involvement of microsomal vesicles in part of the sensitivity of carnitine palmitoyltransferase I to malonyl-CoA inhibition in mitochondrial fractions of rat liver. 1994 Biochem. J. pmid:7998995
Roughan G A semi-preparative enzymic synthesis of malonyl-CoA from [14C]acetate and 14CO2: labelling in the 1, 2 or 3 position. 1994 Biochem. J. pmid:8002939
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Brass EP et al. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. 1990 Biochem. J. pmid:2327967
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Lloyd AC et al. Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. 1986 Biochem. J. pmid:3800884
Weinstein I et al. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. 1986 Biochem. J. pmid:3800903
Robinson IN and Zammit VA Sensitivity of carnitine acyltransferase I to malonly-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo. 1982 Biochem. J. pmid:7126192
Saggerson ED Does fasting decrease the inhibitory effect of malonyl-CoA on hepatic beta-oxidation? 1982 Biochem. J. pmid:7159415
Saggerson ED and Carpenter CA Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy. 1982 Biochem. J. pmid:7165725
Kolodziej MP and Zammit VA Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes. 1990 Biochem. J. pmid:2327991
Saggerson ED et al. Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation. 1984 Biochem. J. pmid:6508756
Cook GA Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. 1984 Biochem. J. pmid:6525169
Murthy MS and Pande SV Characterization of a solubilized malonyl-CoA-sensitive carnitine palmitoyltransferase from the mitochondrial outer membrane as a protein distinct from the malonyl-CoA-insensitive carnitine palmitoyltransferase of the inner membrane. 1990 Biochem. J. pmid:2363698
Lee GY et al. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. 2004 Biochem. J. pmid:14641110
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008
Child CJ and Shoolingin-Jordan PM Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. 1998 Biochem. J. pmid:9480912
Brady PS and Brady LJ Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. 1986 Biochem. J. pmid:3800962