Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Starvation D013217 47 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Placental Insufficiency D010927 6 associated lipids
Ketosis D007662 13 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypoglycemia D007003 13 associated lipids
Hyperinsulinism D006946 27 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Cleft Lip D002971 8 associated lipids
Body Weight D001835 333 associated lipids
Angina Pectoris D000787 27 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Suo Z et al. Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:11106385
Mulder H et al. Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells. 2001 J. Biol. Chem. pmid:11113153
Kennedy JA et al. Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. 2000 J. Cardiovasc. Pharmacol. pmid:11117381
Lane RH et al. Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats. 2001 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11124150
Suo Z et al. Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11134531
Wang YF et al. Crystallization and preliminary X-ray analysis of the 12S central subunit of transcarboxylase from Propionibacterium shermanii. 2001 Acta Crystallogr. D Biol. Crystallogr. pmid:11173475
Qiu X et al. Refined structures of beta-ketoacyl-acyl carrier protein synthase III. 2001 J. Mol. Biol. pmid:11243824
Li JN et al. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. 2001 Cancer Res. pmid:11245456
Wen J and Kerr RG Purification and characterization of the fatty acid synthase from Bugula neritina. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11250539
Fraser F et al. Distinct kinetics of carnitine palmitoyltransferase i in contact sites and outer membranes of rat liver mitochondria. 2001 J. Biol. Chem. pmid:11274214
Abu-Elheiga L et al. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. 2001 Science pmid:11283375
Ruderman N and Flier JS Cell biology. Chewing the fat--ACC and energy balance. 2001 Science pmid:11286278
Guertl B et al. Metabolic cardiomyopathies. 2000 Int J Exp Pathol pmid:11298185
Nicot C et al. Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes. 2001 Biochemistry pmid:11329295
McGarry JD Travels with carnitine palmitoyltransferase I: from liver to germ cell with stops in between. 2001 Biochem. Soc. Trans. pmid:11356162
Eaton S et al. Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux. 2001 Biochem. Soc. Trans. pmid:11356163
Broadway NM et al. Microsomal malonyl-CoA-sensitive carnitine acyltransferase. 2001 Biochem. Soc. Trans. pmid:11356165
Zammit VA et al. Structure-function relationships of the liver and muscle isoforms of carnitine palmitoyltransferase I. 2001 Biochem. Soc. Trans. pmid:11356169
Hegardt FG et al. Post-transcriptional regulation of rat carnitine octanoyltransferase. 2001 Biochem. Soc. Trans. pmid:11356174
Kim YS et al. Malonyl-CoA decarboxylase from Mycobacterium tuberculosis and Pseudomonas fluorescens. 1979 Arch. Biochem. Biophys. pmid:114118
Dagher Z et al. Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. 2001 Circ. Res. pmid:11420304
Morita H et al. Novel polyketides synthesized with a higher plant stilbene synthase. 2001 Eur. J. Biochem. pmid:11432743
Kreuzaler F et al. Flavanone synthase from Petroselinum hortense. Molecular weight, subunit composition, size of messenger RNA, and absence of pantetheinyl residue. 1979 Eur. J. Biochem. pmid:114396
Brown NF et al. Molecular characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme. 2001 J. Lipid Res. pmid:11441142
Thupari JN et al. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. 2001 Biochem. Biophys. Res. Commun. pmid:11444828
Eaton S et al. Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. 2001 Biochem. Biophys. Res. Commun. pmid:11444876
Hamdan M et al. Inhibition of mitochondrial carnitine palmitoyltransferase-1 by a trimetazidine derivative, S-15176. 2001 Pharmacol. Res. pmid:11516258
Rodríguez E et al. Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). 2001 Appl. Environ. Microbiol. pmid:11526020
Rangan VS et al. Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro. 2001 Biochemistry pmid:11535054
Jahnke LL and Diggs K Evidence for the synthesis of the multi-positional isomers of monounsaturated fatty acid in Methylococcus capsusatus by the anaerobic pathway. 1989 FEMS Microbiol. Lett. pmid:11542184
Surendran S et al. Malonyl CoA decarboxylase deficiency: C to T transition in intron 2 of the MCD gene. 2001 J. Neurosci. Res. pmid:11550227
Morillas M et al. Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity. 2001 J. Biol. Chem. pmid:11553629
Doenst T et al. Load-induced changes in vivo alter substrate fluxes and insulin responsiveness of rat heart in vitro. 2001 Metab. Clin. Exp. pmid:11555843
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Moon YA et al. Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. 2001 J. Biol. Chem. pmid:11567032
Reszko AE et al. Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. 2001 Anal. Biochem. pmid:11673897
Martini WZ et al. Alteration of hepatic fatty acid metabolism after burn injury in pigs. 2001 Nov-Dec JPEN J Parenter Enteral Nutr pmid:11688934
Jackson VN et al. Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme. 2001 Biochemistry pmid:11724576
Campbell FM et al. A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. 2002 J. Biol. Chem. pmid:11734553
Richards JG et al. Lipid oxidation fuels recovery from exhaustive exercise in white muscle of rainbow trout. 2002 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11742827
Reeves CD et al. Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations. 2001 Biochemistry pmid:11747421
Ido Y et al. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. 2002 Diabetes pmid:11756336
Nicot C et al. Pig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivity. 2002 J. Biol. Chem. pmid:11790778
Morillas M et al. Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain. 2002 J. Biol. Chem. pmid:11790793
Kim JY et al. Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11934665
Hügler M et al. Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO(2) fixation. 2002 J. Bacteriol. pmid:11948153
Jez JM et al. Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:11959984
Salles J et al. Fatty acid synthase expression during peripheral nervous system myelination. 2002 Brain Res. Mol. Brain Res. pmid:12007831
Atkinson LL et al. Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis. 2002 J. Biol. Chem. pmid:12058043
Thupari JN et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12060712