Malonyl-coa

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Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Starvation D013217 47 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Placental Insufficiency D010927 6 associated lipids
Ketosis D007662 13 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypoglycemia D007003 13 associated lipids
Hyperinsulinism D006946 27 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Cleft Lip D002971 8 associated lipids
Body Weight D001835 333 associated lipids
Angina Pectoris D000787 27 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Brown NF et al. Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. 1997 Biochem. J. pmid:9355756
Roughan PG Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. 1997 Biochem. J. pmid:9355762
Ruderman NB et al. Lipid abnormalities in muscle of insulin-resistant rodents. The malonyl CoA hypothesis. 1997 Ann. N. Y. Acad. Sci. pmid:9329757
Watanabe K et al. Fatty acid synthesis of an eicosapentaenoic acid-producing bacterium: de novo synthesis, chain elongation, and desaturation systems. 1997 J. Biochem. pmid:9378728
Zhu H et al. Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I. 1997 Arch. Biochem. Biophys. pmid:9344464
Oakes ND et al. Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. 1997 Diabetes pmid:9392490
Rasmussen BB and Winder WW Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. 1997 J. Appl. Physiol. pmid:9338417
Saha AK et al. Malonyl-CoA regulation in skeletal muscle: its link to cell citrate and the glucose-fatty acid cycle. 1997 Am. J. Physiol. pmid:9142886
Power GW and Newsholme EA Dietary fatty acids influence the activity and metabolic control of mitochondrial carnitine palmitoyltransferase I in rat heart and skeletal muscle. 1997 J. Nutr. pmid:9349840
Hutber CA et al. Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise. 1997 J. Appl. Physiol. pmid:9390963
Merrill GF et al. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. 1997 Am. J. Physiol. pmid:9435525
Fraser F et al. Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane. 1997 Biochem. J. pmid:9169604
Preisig-Müller R et al. Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening. 1997 Biochemistry pmid:9204882
de Vries Y et al. Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris. 1997 Biochemistry pmid:9136891
Rangan VS and Smith S Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue. 1997 J. Biol. Chem. pmid:9115261
Luthria DL et al. Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. 1997 Biochem. Biophys. Res. Commun. pmid:9144553
Chohnan S et al. Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. 1997 Appl. Environ. Microbiol. pmid:9023936
Broadway NM and Saggerson ED Effect of membrane environment on the activity and inhibitability by malonyl-CoA of the carnitine acyltransferase of hepatic microsomal membranes. 1997 Biochem. J. pmid:9065760
Maurer I and Zierz S Carnitine palmitoyltransferase in patients with cardiac ischemia due to atherosclerotic coronary artery disease and in patients with idiopathic dilated cardiomyopathy. 1997 May-Jun Cardiology pmid:9129847
Carreras CW and Khosla C Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase. 1998 Biochemistry pmid:9518007
Blázquez C et al. Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes. 1998 J. Neurochem. pmid:9751193
Goodwin GW et al. Regulation of energy metabolism of the heart during acute increase in heart work. 1998 J. Biol. Chem. pmid:9792661
Cohen I et al. The N-terminal domain of rat liver carnitine palmitoyltransferase 1 mediates import into the outer mitochondrial membrane and is essential for activity and malonyl-CoA sensitivity. 1998 J. Biol. Chem. pmid:9792707
Swanson ST et al. Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues. 1998 Biochem. J. pmid:9794789
Hunter SC and Ohlrogge JB Regulation of spinach chloroplast acetyl-CoA carboxylase. 1998 Arch. Biochem. Biophys. pmid:9808758
Rangan VS et al. Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits. 1998 J. Biol. Chem. pmid:9857025
Chohnan S et al. Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses. 1998 Biosci. Biotechnol. Biochem. pmid:9692193
Shi J et al. Deletion of the conserved first 18 N-terminal amino acid residues in rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA sensitivity and binding. 1998 Biochemistry pmid:9692998
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Odland LM et al. Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans. 1998 Am. J. Physiol. pmid:9611159
Antinozzi PA et al. Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. 1998 J. Biol. Chem. pmid:9632669
Velasco G et al. Malonyl-CoA-independent acute control of hepatic carnitine palmitoyltransferase I activity. Role of Ca2+/calmodulin-dependent protein kinase II and cytoskeletal components. 1998 J. Biol. Chem. pmid:9705278
Holness MJ et al. Impact of protein restriction on the regulation of cardiac carnitine palmitoyltransferase by malonyl-CoA. 1998 J. Mol. Cell. Cardiol. pmid:9710806
Roche E et al. Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. 1998 Diabetes pmid:9648832
Maurer I et al. Carnitine acyltransferases are not changed in Alzheimer disease. 1998 Alzheimer Dis Assoc Disord pmid:9651134
Hoppel CL et al. The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria. 1998 J. Biol. Chem. pmid:9722587
Winder WW Malonyl-CoA--regulator of fatty acid oxidation in muscle during exercise. 1998 Exerc Sport Sci Rev pmid:9696987
Velasco G et al. Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components. 1998 FEBS Lett. pmid:9845345
Komatsu M and Sharp GW Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+. 1998 Diabetes pmid:9519739
Matharu AL et al. MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor. 1998 Chem. Biol. pmid:9862793
Santarelli X et al. Arginyl residues are involved in acyl-CoA binding to the elongase from etiolated leek seedlings. 1998 Biochim. Biophys. Acta pmid:9555095
Schmidt I and Herpin P Carnitine palmitoyltransferase I (CPT I) activity and its regulation by malonyl-CoA are modulated by age and cold exposure in skeletal muscle mitochondria from newborn pigs. 1998 J. Nutr. pmid:9566999
Abdel-aleem S et al. Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. 1998 Mol. Cell. Biochem. pmid:9546635
Rasmussen BB et al. Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase. 1998 J. Appl. Physiol. pmid:9804562
Merrill GF et al. Influence of malonyl-CoA and palmitate concentration on rate of palmitate oxidation in rat muscle. 1998 J. Appl. Physiol. pmid:9804598
Zhang S and Kim KH Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. 1998 Cell. Signal. pmid:9502115
Adams SH et al. Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat. 1998 Biol. Reprod. pmid:9828184
Fernandes ND and Kolattukudy PE A newly identified methyl-branched chain fatty acid synthesizing enzyme from Mycobacterium tuberculosis var. bovis BCG. 1998 J. Biol. Chem. pmid:9446591
An JH and Kim YS A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli. 1998 Eur. J. Biochem. pmid:9826185
Wang D et al. The liver isoform of carnitine palmitoyltransferase I is activated in neonatal rat cardiac myocytes by hypoxia. 1998 Mol. Cell. Biochem. pmid:9546643
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497
Hitchman TS et al. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. 1998 Chem. Biol. pmid:9479478
Child CJ and Shoolingin-Jordan PM Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. 1998 Biochem. J. pmid:9480912
Domergue F et al. Evidence that oleoyl-CoA and ATP-dependent elongations coexist in rapeseed (Brassica napus L.). 1999 Eur. J. Biochem. pmid:10406955
Jackson VN et al. Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster. 1999 Biochem. J. pmid:10417309
Bao W et al. The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. 1999 J. Bacteriol. pmid:10419974
Zhou P et al. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. 1999 Chem. Biol. pmid:10421763
Sugden MC et al. Hyperthyroidism facilitates cardiac fatty acid oxidation through altered regulation of cardiac carnitine palmitoyltransferase: studies in vivo and with cardiac myocytes. 1999 Horm. Metab. Res. pmid:10422724
Kozaki A and Sasaki Y Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. 1999 Biochem. J. pmid:10215591
Saha AK et al. Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. 1999 Am. J. Physiol. pmid:10362615
Kantor PF et al. Fatty acid oxidation in the reperfused ischemic heart. 1999 Am. J. Med. Sci. pmid:10408755
Shi J et al. A single amino acid change (substitution of glutamate 3 with alanine) in the N-terminal region of rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA inhibition and high affinity binding. 1999 J. Biol. Chem. pmid:10092622
Blázquez C et al. The stimulation of ketogenesis by cannabinoids in cultured astrocytes defines carnitine palmitoyltransferase I as a new ceramide-activated enzyme. 1999 J. Neurochem. pmid:10098887
Goodwin GW and Taegtmeyer H Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation. 1999 Am. J. Physiol. pmid:10516138
Funa N et al. A new pathway for polyketide synthesis in microorganisms. 1999 Nature pmid:10476972
Sargueil F et al. High metabolism and subsequent elongation of 3-hydroxyeicosanoyl-CoA in very-long-chain fatty acid deficient PNS of Trembler mice. 1999 Neurosci. Lett. pmid:10505644
Zammit VA The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. 1999 Biochem. J. pmid:10527927
Dreier J et al. Kinetic analysis of the actinorhodin aromatic polyketide synthase. 1999 J. Biol. Chem. pmid:10455191
Sleboda J et al. Short-term regulation of carnitine palmitoyltransferase I in cultured rat hepatocytes: spontaneous inactivation and reactivation by fatty acids. 1999 Biochim. Biophys. Acta pmid:9989283
Ruderman NB et al. Malonyl-CoA, fuel sensing, and insulin resistance. 1999 Am. J. Physiol. pmid:9886945
Menendez C et al. Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation. 1999 J. Bacteriol. pmid:9973333
Hoenke S and Dimroth P Formation of catalytically active acetyl-S-malonate decarboxylase requires malonyl-coenzyme A:acyl carrier protein transacylase as auxiliary enzyme [corrected]. 1999 Eur. J. Biochem. pmid:9914491
Laybutt DR et al. Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat. 1999 Am. J. Physiol. pmid:10600797
New KJ et al. Comparisons of flux control exerted by mitochondrial outer-membrane carnitine palmitoyltransferase over ketogenesis in hepatocytes and mitochondria isolated from suckling or adult rats. 1999 Eur. J. Biochem. pmid:10092853
Richardson MT et al. Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase. 1999 Metab. Eng. pmid:10935930
Abo-Hashema KA et al. Liver mitochondria, confirmed as intact by complete suppression of succinate uptake and oxidation, possess a carnitine palmitoyltransferase I that is totally inhibited by malonyl CoA. 1999 Biochem. Biophys. Res. Commun. pmid:10329463
Guertl B et al. Metabolic cardiomyopathies. 2000 Int J Exp Pathol pmid:11298185
Kantor PF et al. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. 2000 Circ. Res. pmid:10720420
Morillas M et al. Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver. 2000 FEBS Lett. pmid:10648838
Shi J et al. The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high-affinity binding. 2000 Biochemistry pmid:10651636
Jez JM et al. Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. 2000 Biochemistry pmid:10653632
Kennedy JA et al. Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. 2000 J. Cardiovasc. Pharmacol. pmid:11117381
Odland LM et al. Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise. 2000 J. Appl. Physiol. pmid:11090589
Winder WW and Holmes BF Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated. 2000 J. Appl. Physiol. pmid:11090599
McGarry JD Malonyl-CoA and satiety? Food for thought. 2000 Trends Endocrinol. Metab. pmid:11091115
Suo Z et al. Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:11106385
Roduit R et al. Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell. 2000 J. Biol. Chem. pmid:10967113
Jackson VN et al. Identification of positive and negative determinants of malonyl-CoA sensitivity and carnitine affinity within the amino termini of rat liver- and muscle-type carnitine palmitoyltransferase I. 2000 J. Biol. Chem. pmid:10969089
Goodwin GW and Taegtmeyer H Improved energy homeostasis of the heart in the metabolic state of exercise. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11009433
Suh DY et al. Evidence for catalytic cysteine-histidine dyad in chalcone synthase. 2000 Biochem. Biophys. Res. Commun. pmid:10973790
Hamilton C and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes. 2000 Biochem. J. pmid:10926826
Loftus TM et al. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. 2000 Science pmid:10875926
Kerner J and Hoppel C Fatty acid import into mitochondria. 2000 Biochim. Biophys. Acta pmid:10856709
Chien D et al. Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913024
Gura T Obesity. Enzyme blocker prompts mice to shed weight. 2000 Science pmid:10917820
Guzmán M et al. Do cytoskeletal components control fatty acid translocation into liver mitochondria? 2000 Trends Endocrinol. Metab. pmid:10675890
Starritt EC et al. Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10710500
Pizer ES et al. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. 2000 Cancer Res. pmid:10667561
Hickson-Bick DL et al. Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes. 2000 J. Mol. Cell. Cardiol. pmid:10731449
Hoenke S et al. Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. 2000 Biochemistry pmid:11052675