Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Starvation D013217 47 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Placental Insufficiency D010927 6 associated lipids
Ketosis D007662 13 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypoglycemia D007003 13 associated lipids
Hyperinsulinism D006946 27 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Cleft Lip D002971 8 associated lipids
Body Weight D001835 333 associated lipids
Angina Pectoris D000787 27 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 | Total 20

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Relat J et al. Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme. 2004 Biochemistry pmid:15449958
Cheng L et al. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. 2004 Nat. Med. pmid:15475963
Faye A et al. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity. 2005 Biochem. J. pmid:15498023
Zhang YQ et al. Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans. 2004 Genetics pmid:15514053
Peluso G et al. Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells. 2005 J. Cell. Physiol. pmid:15515015
Oguro S et al. Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. 2004 Biochem. Biophys. Res. Commun. pmid:15530429
Nicot C et al. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. 2004 Biochem. Biophys. Res. Commun. pmid:15541339
Kashfi K and Cook GA Proteinase treatment of intact hepatic mitochondria has differential effects on inhibition of carnitine palmitoyltransferase by different inhibitors. 1992 Biochem. J. pmid:1554374
Raney MA et al. AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15547141
Prentki M et al. Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. 1992 J. Biol. Chem. pmid:1556096
Yu X et al. Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. 2004 Diabetologia pmid:15578153
Liu H et al. Cysteine-scanning mutagenesis of muscle carnitine palmitoyltransferase I reveals a single cysteine residue (Cys-305) is important for catalysis. 2005 J. Biol. Chem. pmid:15579906
Shirai Y et al. Metabolic regulation of leptin production in adipocytes: a role of fatty acid synthesis intermediates. 2004 J. Nutr. Biochem. pmid:15590268
Foster DW The role of the carnitine system in human metabolism. 2004 Ann. N. Y. Acad. Sci. pmid:15590999
Dulloo AG et al. Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity. 2004 Int. J. Obes. Relat. Metab. Disord. pmid:15592483
Menendez JA et al. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis. 2005 Med. Hypotheses pmid:15607568
Bian F et al. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. 2005 J. Biol. Chem. pmid:15611129
Jeong JC et al. Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation. 2005 J. Am. Chem. Soc. pmid:15631450
Taylor EB et al. Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15644453
Koves TR et al. Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. 2005 Am. J. Physiol., Cell Physiol. pmid:15647392
Oh W et al. Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15677334
Herrero L et al. Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion. 2005 Diabetes pmid:15677504
Abe I et al. A plant type III polyketide synthase that produces pentaketide chromone. 2005 J. Am. Chem. Soc. pmid:15686354
Funa N et al. A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides. 2005 J. Biol. Chem. pmid:15701630
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Trivedi OA et al. Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid. 2005 Mol. Cell pmid:15749014
Miyahisa I et al. Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. 2005 Appl. Microbiol. Biotechnol. pmid:15770480
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Planavila A et al. Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice. 2005 Biochem. Pharmacol. pmid:15794940
Griffin MJ and Sul HS Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c. 2004 IUBMB Life pmid:15814457
King KL et al. Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15821035
Giordano A et al. tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. 2005 Cell Death Differ. pmid:15846373
Kikuchi S et al. Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG. 1992 Arch. Biochem. Biophys. pmid:1586161
Woldegiorgis G et al. Restoration of malonyl-CoA sensitivity of soluble rat liver mitochondria carnitine palmitoyltransferase by reconstitution with a partially purified malonyl-CoA binding protein. 1992 Arch. Biochem. Biophys. pmid:1586164
Nozu F et al. Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats. 1992 Hepatology pmid:1592350
Kamoun P Valine is a precursor of propionyl-CoA. 1992 Trends Biochem. Sci. pmid:1595124
Dowell P et al. Monitoring energy balance: metabolites of fatty acid synthesis as hypothalamic sensors. 2005 Annu. Rev. Biochem. pmid:15952896
Mingrone G et al. Leptin pulsatility in formerly obese women. 2005 FASEB J. pmid:15955844
Assifi MM et al. AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15956049
Lelliott CJ et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. 2005 FASEB J. pmid:15985534
Mizuarai S et al. Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. 2005 J. Biol. Chem. pmid:16027120
Neschen S et al. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. 2005 Cell Metab. pmid:16054099
Brusselmans K et al. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. 2005 Cancer Res. pmid:16061653
Abu-Elheiga L et al. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16103361
Gambert S et al. Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. 2005 Biochim. Biophys. Acta pmid:16153888
Cha SH et al. Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16203972
Spiteller D et al. A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue. 2005 Angew. Chem. Int. Ed. Engl. pmid:16208728
Hu Z et al. A role for hypothalamic malonyl-CoA in the control of food intake. 2005 J. Biol. Chem. pmid:16219771
Dann HM and Drackley JK Carnitine palmitoyltransferase I in liver of periparturient dairy cows: effects of prepartum intake, postpartum induction of ketosis, and periparturient disorders. 2005 J. Dairy Sci. pmid:16230690
Kraegen EW et al. Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16234268