Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Starvation D013217 47 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Placental Insufficiency D010927 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Loss D015431 56 associated lipids
Myocardial Stunning D017682 10 associated lipids
Cleft Lip D002971 8 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Malonyl-coa

Download all related citations
Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Koyuncu E et al. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. 2013 PLoS Pathog. pmid:23696731
Albanesi D et al. Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. 2013 PLoS Pathog. pmid:23300457
Serviddio G et al. Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet. 2011 PLoS ONE pmid:21909411
ElAzzouny MA et al. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. 2015 PLoS ONE pmid:26107620
Liu C et al. Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. 2013 PLoS ONE pmid:24073271
Moore RG et al. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. 2012 PLoS ONE pmid:22509304
Suh MC et al. What limits production of unusual monoenoic fatty acids in transgenic plants? 2002 Planta pmid:12172841
Kim DH et al. Molecular characterization of flavonoid malonyltransferase from Oryza sativa. 2009 Nov-Dec Plant Physiol. Biochem. pmid:19733090
Metz JG et al. Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. 2009 Plant Physiol. Biochem. pmid:19272783
Raharjo TJ et al. Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa. 2004 Plant Physiol. Biochem. pmid:15120113
Focke M et al. Fatty acid biosynthesis in mitochondria of grasses: malonyl-coenzyme A is generated by a mitochondrial-localized acetyl-coenzyme A carboxylase. 2003 Plant Physiol. pmid:12972648
Hammerbacher A et al. Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection. 2011 Plant Physiol. pmid:21865488
Levitan O et al. An RNA interference knock-down of nitrate reductase enhances lipid biosynthesis in the diatom Phaeodactylum tricornutum. 2015 Plant J. pmid:26473332
Bertoni G A key step in phlorotannin biosynthesis revealed. 2013 Plant Cell pmid:23995082
Falk KL et al. Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa. 2004 Phytochemistry pmid:15110687
Eckermann C et al. Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. 2003 Phytochemistry pmid:14568070
Morash AJ and McClelland GB Regulation of carnitine palmitoyltransferase (CPT) I during fasting in rainbow trout (Oncorhynchus mykiss) promotes increased mitochondrial fatty acid oxidation. 2011 Nov-Dec Physiol. Biochem. Zool. pmid:22030855
Gao S et al. Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. 2013 Physiol. Behav. pmid:23680429
Gao S et al. Hypothalamic malonyl-CoA and the control of food intake. 2013 Physiol. Behav. pmid:23988346
Cahová M et al. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. 2007 Physiol Res pmid:16497094
Szkudelski T Intracellular mediators in regulation of leptin secretion from adipocytes. 2007 Physiol Res pmid:17184148
Lopaschuk GD et al. Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite. 2010 Pharmacol. Rev. pmid:20392806
Hamdan M et al. Inhibition of mitochondrial carnitine palmitoyltransferase-1 by a trimetazidine derivative, S-15176. 2001 Pharmacol. Res. pmid:11516258
Prada CE et al. Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy. 2012 Pediatrics pmid:22778304
Reindl BA et al. Sani-cloth wipe mimics rare enzyme deficiency malonic aciduria on newborn screen. 2012 Pediatrics pmid:23071203
Yatscoff MA et al. Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart. 2008 Pediatr. Res. pmid:18614968
Kharel MK et al. Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. 2010 Org. Lett. pmid:20486694
Loubière C et al. Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells. 2015 Oncotarget pmid:26002551
Celik A et al. Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia. 2009 Oncol. Rep. pmid:19288015
Fritz V et al. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. 2013 Oncogene pmid:23208508
Ruderman NB and Saha AK Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A. 2006 Obesity (Silver Spring) pmid:16642960
Rosa G et al. Decreased muscle acetyl-coenzyme A carboxylase 2 mRNA and insulin resistance in formerly obese subjects. 2003 Obes. Res. pmid:14627750
Sargueil F et al. High metabolism and subsequent elongation of 3-hydroxyeicosanoyl-CoA in very-long-chain fatty acid deficient PNS of Trembler mice. 1999 Neurosci. Lett. pmid:10505644
Sucajtys-Szulc E et al. Differential effect of prolonged food restriction and fasting on hypothalamic malonyl-CoA concentration and expression of orexigenic and anorexigenic neuropeptides genes in rats. 2010 Neuropeptides pmid:20004973
Trevisan CP et al. Myoglobinuria and carnitine palmityltransferase (CPT) deficiency: studies with malonyl-CoA suggest absence of only CPT-II. 1984 Neurology pmid:6538275
Funa N et al. A new pathway for polyketide synthesis in microorganisms. 1999 Nature pmid:10476972
Knobloch M et al. Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. 2013 Nature pmid:23201681
Cheng L et al. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. 2004 Nat. Med. pmid:15475963
Wortman MD et al. C75 inhibits food intake by increasing CNS glucose metabolism. 2003 Nat. Med. pmid:12724740
Sloan JL et al. Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria. 2011 Nat. Genet. pmid:21841779
Ruderman N and Prentki M AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. 2004 Nat Rev Drug Discov pmid:15060529
Koeppen AH et al. Fatty acid biosynthesis in Wallerian degeneration of rat sciatic nerve. 1979 Sep-Oct Muscle Nerve pmid:40126
Vladutiu GD et al. Carnitine palmitoyl transferase deficiency in malignant hyperthermia. 1993 Muscle Nerve pmid:8515756
Downs SM et al. Fatty acid oxidation and meiotic resumption in mouse oocytes. 2009 Mol. Reprod. Dev. pmid:19455666
Schink B An alternative to the glyoxylate shunt. 2009 Mol. Microbiol. pmid:19682245
Schujman GE et al. A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism. 2008 Mol. Microbiol. pmid:18384517
Lemoine Y et al. To be free or not: the fate of pimelate in Bacillus sphaericus and in Escherichia coli. 1996 Mol. Microbiol. pmid:8830257
Xue J et al. Novel compound heterozygous mutation of MLYCD in a Chinese patient with malonic aciduria. 2012 Mol. Genet. Metab. pmid:22104738
Wolfgang MJ and Lane MD Hypothalamic malonyl-coenzyme A and the control of energy balance. 2008 Mol. Endocrinol. pmid:18356287
Natarajan S et al. Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP. 2012 Mol. Cells pmid:22134719