Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Starvation D013217 47 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Placental Insufficiency D010927 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Loss D015431 56 associated lipids
Myocardial Stunning D017682 10 associated lipids
Cleft Lip D002971 8 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Li S et al. Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase. 2007 J. Biol. Chem. pmid:17331946
López M et al. Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. 2007 Bioessays pmid:17295284
Abe T et al. Structure function analysis of benzalacetone synthase from Rheum palmatum. 2007 Bioorg. Med. Chem. Lett. pmid:17383877
Gao L et al. Simultaneous quantification of malonyl-CoA and several other short-chain acyl-CoAs in animal tissues by ion-pairing reversed-phase HPLC/MS. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17442642
Leonard E et al. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. 2007 Appl. Environ. Microbiol. pmid:17468269
López-Viñas E et al. Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A. 2007 J. Biol. Chem. pmid:17452323
Wang X et al. Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. 2007 Anal. Biochem. pmid:17316539
Kadokawa H et al. Links between de novo fatty acid synthesis and leptin secretion in bovine adipocytes. 2007 J. Vet. Med. Sci. pmid:17409636
Cheng D et al. Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes. 2007 Protein Expr. Purif. pmid:16854592
Folmes CD and Lopaschuk GD Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. 2007 Cardiovasc. Res. pmid:17126822
Guo W et al. Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17148751
Sebastián D et al. CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17062841
Szkudelski T Intracellular mediators in regulation of leptin secretion from adipocytes. 2007 Physiol Res pmid:17184148
Springob K et al. A polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones. 2007 FEBS J. pmid:17229146
Wallace DM et al. Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors. 2007 Bioorg. Med. Chem. Lett. pmid:17234415
Badaoui B et al. Goat acetyl-coenzyme A carboxylase alpha: molecular characterization, polymorphism, and association with milk traits. 2007 J. Dairy Sci. pmid:17235183
Harada N et al. Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice. 2007 Mol. Cell. Biol. pmid:17210641
Bian F et al. Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart. 2006 J. Mol. Cell. Cardiol. pmid:17020764
Beha A et al. Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16380389
Murase T et al. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. 2006 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:16410398
Holloway GP et al. Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise. 2006 J. Physiol. (Lond.) pmid:16357012
Kraegen EW et al. Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16234268
Bell JA et al. Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA. 2006 Diabetologia pmid:16868746
Borthwick K et al. The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity. 2006 J. Biol. Chem. pmid:16908527
Schujman GE et al. Structural basis of lipid biosynthesis regulation in Gram-positive bacteria. 2006 EMBO J. pmid:16932747
Tang GL et al. Polyketide chain skipping mechanism in the biosynthesis of the hybrid nonribosomal peptide-polyketide antitumor antibiotic leinamycin in Streptomyces atroolivaceus S-140. 2006 J. Nat. Prod. pmid:16562841
Lindén D et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. 2006 FASEB J. pmid:16507761
Collier CA et al. Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16478780
Kuhl JE et al. Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16434556
Cheng JF et al. Synthesis and structure-activity relationship of small-molecule malonyl coenzyme A decarboxylase inhibitors. 2006 J. Med. Chem. pmid:16509570
Wolfgang MJ and Lane MD The role of hypothalamic malonyl-CoA in energy homeostasis. 2006 J. Biol. Chem. pmid:17018521
Cha SH et al. Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:17030788
Bandyopadhyay GK et al. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. 2006 Diabetes pmid:16873691
Saha AK et al. AMPK regulation of the growth of cultured human keratinocytes. 2006 Biochem. Biophys. Res. Commun. pmid:16949049
Hayashi O and Satoh K Determination of acetyl-CoA and malonyl-CoA in germinating rice seeds using the LC-MS/MS technique. 2006 Biosci. Biotechnol. Biochem. pmid:17090944
Nolan CJ et al. Fatty acid signaling in the beta-cell and insulin secretion. 2006 Diabetes pmid:17130640
Minkler PE et al. Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry. 2006 Anal. Biochem. pmid:16545769
Wolfgang MJ et al. The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16651524
Ruderman NB and Saha AK Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A. 2006 Obesity (Silver Spring) pmid:16642960
López M et al. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. 2006 Diabetes pmid:16644689
Gu YG et al. Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors. 2006 J. Med. Chem. pmid:16789734
Neels JG and Olefsky JM Cell signaling. A new way to burn fat. 2006 Science pmid:16794069
Mao J et al. Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16717184
Oefner C et al. Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography. 2006 Acta Crystallogr. D Biol. Crystallogr. pmid:16699188
Pender C et al. Expression of genes regulating malonyl-CoA in human skeletal muscle. 2006 J. Cell. Biochem. pmid:16721829
Wolfgang MJ and Lane MD Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system. 2006 Annu. Rev. Nutr. pmid:16704352
Onay-Besikci A and Sambandam N Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply. 2006 Can. J. Physiol. Pharmacol. pmid:17218986
Trivedi OA et al. Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid. 2005 Mol. Cell pmid:15749014
Oh W et al. Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15677334
Herrero L et al. Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion. 2005 Diabetes pmid:15677504