Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Starvation D013217 47 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Placental Insufficiency D010927 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Loss D015431 56 associated lipids
Myocardial Stunning D017682 10 associated lipids
Cleft Lip D002971 8 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Brown NF et al. Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. 1997 Biochem. J. pmid:9355756
Roughan PG Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. 1997 Biochem. J. pmid:9355762
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Moir AM and Zammit VA Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume. 1995 Biochem. J. pmid:7848296
Jackson VN et al. Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster. 1999 Biochem. J. pmid:10417309
Kozaki A and Sasaki Y Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. 1999 Biochem. J. pmid:10215591
Saggerson ED Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA. 1982 Biochem. J. pmid:7092822
Zammit VA The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. 1999 Biochem. J. pmid:10527927
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Saggerson ED et al. Effects of thyroidectomy and starvation on the activity and properties of hepatic carnitine palmitoyltransferase. 1982 Biochem. J. pmid:7165724
Geelen MJ Medium-chain fatty acids as short-term regulators of hepatic lipogenesis. 1994 Biochem. J. pmid:7915110
Niot I et al. Involvement of microsomal vesicles in part of the sensitivity of carnitine palmitoyltransferase I to malonyl-CoA inhibition in mitochondrial fractions of rat liver. 1994 Biochem. J. pmid:7998995
Grantham BD and Zammit VA Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA. 1986 Biochem. J. pmid:3954755
Guzman M et al. Evidence against direct involvement of phosphorylation in the activation of carnitine palmitoyltransferase by okadaic acid in rat hepatocytes. 1994 Biochem. J. pmid:8010950
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Mynatt RL et al. Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids. 1994 Biochem. J. pmid:8192665
Bird MI and Saggerson ED Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity. 1984 Biochem. J. pmid:6487267
Brass EP et al. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. 1990 Biochem. J. pmid:2327967
Marsh EN et al. Subunit interactions in Propionibacterium shermanii methylmalonyl-CoA mutase studied by analytical ultracentrifugation. 1989 Biochem. J. pmid:2569862
Zammit VA et al. Target size analysis by radiation inactivation of carnitine palmitoyltransferase activity and malonyl-CoA binding in outer membranes from rat liver mitochondria. 1989 Biochem. J. pmid:2604707
Derrick JP and Ramsay RR L-carnitine acyltransferase in intact peroxisomes is inhibited by malonyl-CoA. 1989 Biochem. J. pmid:2590167
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Mills SE et al. Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I. 1984 Biochem. J. pmid:6743235
Faye A et al. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity. 2005 Biochem. J. pmid:15498023
Walker TA et al. Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris. 1981 Biochem. J. pmid:6803763
Zammit VA Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA. 1984 Biochem. J. pmid:6712621
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Cook GA et al. Altered sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA in ketotic diabetic rats. 1984 Biochem. J. pmid:6426472
Cook GA and Cox KA Hysteretic behaviour of carnitine palmitoyltransferase. The effect of preincubation with malonyl-CoA. 1986 Biochem. J. pmid:3790097
Lloyd AC et al. Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. 1986 Biochem. J. pmid:3800884
Saggerson ED and Carpenter CA Sensitivity of brown-adipose-tissue carnitine palmitoyltransferase to inhibition by malonyl-CoA. 1982 Biochem. J. pmid:7115330
Weinstein I et al. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. 1986 Biochem. J. pmid:3800903
Robinson IN and Zammit VA Sensitivity of carnitine acyltransferase I to malonly-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo. 1982 Biochem. J. pmid:7126192
Saggerson ED Does fasting decrease the inhibitory effect of malonyl-CoA on hepatic beta-oxidation? 1982 Biochem. J. pmid:7159415
Saggerson ED and Carpenter CA Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy. 1982 Biochem. J. pmid:7165725
McGarry JD and Foster DW Importance of experimental conditions in evaluating the malonyl-CoA sensitivity of liver carnitine acyltransferase. Studies with fed and starved rats. 1981 Biochem. J. pmid:7340831
Walker KA et al. Fluazifop, a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. 1988 Biochem. J. pmid:2902848
Kolodziej MP and Zammit VA Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes. 1990 Biochem. J. pmid:2327991
Brady LJ et al. Hepatic mitochondrial inner-membrane properties, beta-oxidation and carnitine palmitoyltransferases A and B. Effects of genetic obesity and starvation. 1986 Biochem. J. pmid:3954744
Saggerson ED et al. Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation. 1984 Biochem. J. pmid:6508756
Zammit VA et al. Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0 degree C and 37 degrees C with a fixed concentration of malonyl-CoA. 1984 Biochem. J. pmid:6477517
Cook GA Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. 1984 Biochem. J. pmid:6525169
Brindle NP et al. Regulation of carnitine palmitoyltransferase activity by malonyl-CoA in mitochondria from sheep liver, a tissue with a low capacity for fatty acid synthesis. 1985 Biochem. J. pmid:4084227
Murthy MS and Pande SV Characterization of a solubilized malonyl-CoA-sensitive carnitine palmitoyltransferase from the mitochondrial outer membrane as a protein distinct from the malonyl-CoA-insensitive carnitine palmitoyltransferase of the inner membrane. 1990 Biochem. J. pmid:2363698
Lee GY et al. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. 2004 Biochem. J. pmid:14641110
Brady LJ et al. Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. 1985 Biochem. J. pmid:4091801
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008
Child CJ and Shoolingin-Jordan PM Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. 1998 Biochem. J. pmid:9480912
Brady PS and Brady LJ Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. 1986 Biochem. J. pmid:3800962