Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Starvation D013217 47 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Placental Insufficiency D010927 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Loss D015431 56 associated lipids
Myocardial Stunning D017682 10 associated lipids
Cleft Lip D002971 8 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Moir AM and Zammit VA Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume. 1995 Biochem. J. pmid:7848296
Saggerson ED and Carpenter CA The effect of malonyl-CoA on overt and latent carnitine acyltransferase activities in rat liver and adipocyte mitochondria. 1983 Biochem. J. pmid:6860313
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Zammit VA The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. 1999 Biochem. J. pmid:10527927
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Saggerson ED et al. Effects of thyroidectomy and starvation on the activity and properties of hepatic carnitine palmitoyltransferase. 1982 Biochem. J. pmid:7165724
Niot I et al. Involvement of microsomal vesicles in part of the sensitivity of carnitine palmitoyltransferase I to malonyl-CoA inhibition in mitochondrial fractions of rat liver. 1994 Biochem. J. pmid:7998995
Roughan G A semi-preparative enzymic synthesis of malonyl-CoA from [14C]acetate and 14CO2: labelling in the 1, 2 or 3 position. 1994 Biochem. J. pmid:8002939
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Brass EP et al. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. 1990 Biochem. J. pmid:2327967
Kolodziej MP and Zammit VA Sensitivity of inhibition of rat liver mitochondrial outer-membrane carnitine palmitoyltransferase by malonyl-CoA to chemical- and temperature-induced changes in membrane fluidity. 1990 Biochem. J. pmid:2268270
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Ghadiminejad I and Saggerson ED The relationship of rat liver overt carnitine palmitoyltransferase to the mitochondrial malonyl-CoA binding entity and to the latent palmitoyltransferase. 1990 Biochem. J. pmid:2241911
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Lloyd AC et al. Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. 1986 Biochem. J. pmid:3800884
Weinstein I et al. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. 1986 Biochem. J. pmid:3800903
Saggerson ED Does fasting decrease the inhibitory effect of malonyl-CoA on hepatic beta-oxidation? 1982 Biochem. J. pmid:7159415
Saggerson ED and Carpenter CA Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy. 1982 Biochem. J. pmid:7165725
Schofield PS et al. Altered interactions between lipogenesis and fatty acid oxidation in regenerating rat liver. 1987 Biochem. J. pmid:3593202
Roughan PG et al. On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts. 1979 Biochem. J. pmid:534525
Kolodziej MP and Zammit VA Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes. 1990 Biochem. J. pmid:2327991
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Saggerson ED et al. Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation. 1984 Biochem. J. pmid:6508756
Cook GA Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. 1984 Biochem. J. pmid:6525169
Bird MI et al. Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. 1985 Biochem. J. pmid:3977877
Murthy MS and Pande SV Characterization of a solubilized malonyl-CoA-sensitive carnitine palmitoyltransferase from the mitochondrial outer membrane as a protein distinct from the malonyl-CoA-insensitive carnitine palmitoyltransferase of the inner membrane. 1990 Biochem. J. pmid:2363698
Lee GY et al. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. 2004 Biochem. J. pmid:14641110
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008
Brady PS and Brady LJ Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. 1986 Biochem. J. pmid:3800962
Henninger C et al. Effects of fenofibrate treatment on fatty acid oxidation in liver mitochondria of obese Zucker rats. 1987 Biochem. Pharmacol. pmid:3663237
Planavila A et al. Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice. 2005 Biochem. Pharmacol. pmid:15794940
Lilly K et al. Effect of etomoxiryl-CoA on different carnitine acyltransferases. 1992 Biochem. Pharmacol. pmid:1739421
Jones CT and Wahle KW Aspects of lipid metabolism in the foetal, neonatal and adult monogastric mammal. 1980 Biochem. Soc. Trans. pmid:6105107
Mynatt RL and Cook GA Modulation of the malonyl-CoA sensitivity of hepatic carnitine palmitoyltransferase (CPT) by phospholipids. 1994 Biochem. Soc. Trans. pmid:7958184
McGarry JD Travels with carnitine palmitoyltransferase I: from liver to germ cell with stops in between. 2001 Biochem. Soc. Trans. pmid:11356162
Eaton S et al. Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux. 2001 Biochem. Soc. Trans. pmid:11356163
Jiffri E et al. Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat. 1996 Biochem. Soc. Trans. pmid:8736922
Broadway NM et al. Microsomal malonyl-CoA-sensitive carnitine acyltransferase. 2001 Biochem. Soc. Trans. pmid:11356165
Zammit VA et al. Structure-function relationships of the liver and muscle isoforms of carnitine palmitoyltransferase I. 2001 Biochem. Soc. Trans. pmid:11356169
Hegardt FG et al. Post-transcriptional regulation of rat carnitine octanoyltransferase. 2001 Biochem. Soc. Trans. pmid:11356174
McGarry JD Malonyl-CoA and carnitine palmitoyltransferase I: an expanding partnership. 1995 Biochem. Soc. Trans. pmid:8566378
Broadway NM and Saggerson ED Microsomal carnitine acyltransferases. 1995 Biochem. Soc. Trans. pmid:8566389
Fraser F et al. Evidence that both the acyl-CoA- and malonyl-CoA binding sites of mitochondrial overt carnitine palmitoyltransferase (CPT I) are exposed on the cytosolic face of the outer membrane. 1996 Biochem. Soc. Trans. pmid:8736842
Lane MD et al. Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure. 2005 Biochem. Soc. Trans. pmid:16246046
Ruderman NB et al. Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. 2003 Biochem. Soc. Trans. pmid:12546685
Hopkins TA et al. AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart. 2003 Biochem. Soc. Trans. pmid:12546686
Bergseth S et al. Is carnitine palmitoyltransferase inhibited by a malonyl-CoA-binding unit in the mitochondria? 1986 Biochem. Soc. Trans. pmid:3743880
Frayn KN The glucose-fatty acid cycle: a physiological perspective. 2003 Biochem. Soc. Trans. pmid:14641007