Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Starvation D013217 47 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Angina Pectoris D000787 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Placental Insufficiency D010927 6 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Loss D015431 56 associated lipids
Myocardial Stunning D017682 10 associated lipids
Cleft Lip D002971 8 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Authors Title Published Journal PubMed Link
McGarry JD Malonyl-CoA and carnitine palmitoyltransferase I: an expanding partnership. 1995 Biochem. Soc. Trans. pmid:8566378
Broadway NM and Saggerson ED Microsomal carnitine acyltransferases. 1995 Biochem. Soc. Trans. pmid:8566389
Carreras CW and Khosla C Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase. 1998 Biochemistry pmid:9518007
Meehan MJ et al. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. 2011 Biochemistry pmid:21069965
Martinez MA et al. A novel role of malonyl-ACP in lipid homeostasis. 2010 Biochemistry pmid:20201588
Shi J et al. Deletion of the conserved first 18 N-terminal amino acid residues in rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA sensitivity and binding. 1998 Biochemistry pmid:9692998
Rangan VS et al. Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro. 2001 Biochemistry pmid:11535054
Reeves CD et al. Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations. 2001 Biochemistry pmid:11747421
Nicot C et al. Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes. 2001 Biochemistry pmid:11329295
Florova G et al. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity. 2002 Biochemistry pmid:12173933
Zheng X et al. Substrate binding induces a cooperative conformational change in the 12S subunit of transcarboxylase: Raman crystallographic evidence. 2002 Biochemistry pmid:12196011
Witkowski A et al. Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase. 2002 Biochemistry pmid:12196027
Child CJ et al. Structural similarities between 6-methylsalicylic acid synthase from Penicillium patulum and vertebrate type I fatty acid synthase: evidence from thiol modification studies. 1996 Biochemistry pmid:8823160
Suzuki H et al. Proposed mechanism and functional amino acid residues of malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from flowers of Salvia splendens, a member of the versatile plant acyltransferase family. 2003 Biochemistry pmid:12578391
Prigge ST et al. The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII. 2003 Biochemistry pmid:12549938
Liou GF et al. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases. 2003 Biochemistry pmid:12515555
Shi J et al. The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high-affinity binding. 2000 Biochemistry pmid:10651636
Jez JM et al. Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. 2000 Biochemistry pmid:10653632
Fujii I et al. Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme A by a fungal iterative type I polyketide synthase PKS1. 2000 Biochemistry pmid:10913297
Jackson VN et al. Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme. 2001 Biochemistry pmid:11724576
Mazur MT et al. Site-specific observation of acyl intermediate processing in thiotemplate biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase. 2003 Biochemistry pmid:14621984
Hoenke S et al. Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. 2000 Biochemistry pmid:11052675
Singh SP et al. Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. 2008 Biochemistry pmid:18311940
Tseng CC et al. Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase. 2004 Biochemistry pmid:14744141
Relat J et al. Pig muscle carnitine palmitoyltransferase I (CPTI beta), with low Km for carnitine and low sensitivity to malonyl-CoA inhibition, has kinetic characteristics similar to those of the rat liver (CPTI alpha) enzyme. 2004 Biochemistry pmid:15449958
Preisig-Müller R et al. Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening. 1997 Biochemistry pmid:9204882
de Vries Y et al. Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris. 1997 Biochemistry pmid:9136891
Dunn BJ et al. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. 2014 Biochemistry pmid:24871074
Bernert JT and Sprecher H The effect of bovine serum albumin on partial reactions of palmitoyl-CoA chain elongation by rat liver microsomes. 1978 Biochim. Biophys. Acta pmid:30485
Kashfi K et al. Hepatic carnitine palmitoyltransferase-I has two independent inhibitory binding sites for regulation of fatty acid oxidation. 1994 Biochim. Biophys. Acta pmid:8180250
Ghadiminejad I and Saggerson D A proportion of rat liver mitochondrial carnitine palmitoyltransferase can be made activatable by malonyl-CoA. 1991 Biochim. Biophys. Acta pmid:1911872
Ghadiminejad I and Saggerson D Cholate separates the catalytic and malonyl-CoA-binding components of carnitine palmitoyltransferase from liver outer mitochondrial membranes. 1991 Biochim. Biophys. Acta pmid:2036450
Lund H and Bremer J Carnitine acetyltransferase. Effect of malonyl-CoA, fasting and clofibrate feeding in mitochondria from different tissues. 1983 Biochim. Biophys. Acta pmid:6824710
Kawashima Y and Suzuki Y Role of phosphatidylcholine on microsomal chain elongation and the fate of stearoyl-CoA in rat liver microsomes. 1978 Biochim. Biophys. Acta pmid:667088
Traufeller K et al. Different sensitivities of CPT I and CPT II for inhibition by l-aminocarnitine in human skeletal muscle. 2004 Biochim. Biophys. Acta pmid:14871492
Fiol CJ et al. Effect of malonyl-CoA on the kinetics and substrate cooperativity of membrane-bound carnitine palmitoyltransferase of rat heart mitochondria. 1987 Biochim. Biophys. Acta pmid:3689805
Veerkamp JH and Van Moerkerk HT The effect of malonyl-CoA on fatty acid oxidation in rat muscle and liver mitochondria. 1982 Biochim. Biophys. Acta pmid:7066363
Lund H and Woldegiorgis G Carnitine palmitoyltransferase: separation of enzyme activity and malonyl-CoA binding in rat liver mitochondria. 1986 Biochim. Biophys. Acta pmid:3756194
Lund H Carnitine palmitoyltransferase: characterization of a labile detergent-extracted malonyl-CoA-sensitive enzyme from rat liver mitochondria. 1987 Biochim. Biophys. Acta pmid:3828368
Bremer J The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. 1981 Biochim. Biophys. Acta pmid:7295757
Deana R et al. Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver. 1981 Biochim. Biophys. Acta pmid:6946836
Kashfi K and Cook GA Temperature effects on malonyl-CoA inhibition of carnitine palmitoyltransferase I. 1995 Biochim. Biophys. Acta pmid:7619853
Kerner J and Hoppel C Fatty acid import into mitochondria. 2000 Biochim. Biophys. Acta pmid:10856709
Demirkapi N et al. Evidence against cytochrome b5 involvement in liver microsomal fatty acid elongation. 1991 Biochim. Biophys. Acta pmid:2009301
Katsurada A et al. Effects of dietary nutrients on substrate and effector levels of lipogenic enzymes, and lipogenesis from tritiated water in rat liver. 1986 Biochim. Biophys. Acta pmid:2875738
Giompres P and Packter NM Purification and properties of the polymeric fatty acid synthetase from a filamentous fungus. 1978 Biochim. Biophys. Acta pmid:350287
Bhatia H et al. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. 2014 Biochim. Biophys. Acta pmid:24560669
Bieber LL and Wagner M Effect of pH and acyl-CoA chain length on the conversion of heart mitochondrial CPT-I/CPTo to a high affinity, malonyl-CoA-inhibited state. 1996 Biochim. Biophys. Acta pmid:8765129
Christophersen BO et al. Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells. 1982 Biochim. Biophys. Acta pmid:6812639
McGarry JD et al. Characteristics of fatty acid oxidation in rat liver homogenates and the inhibitory effect of malonyl-CoA. 1978 Biochim. Biophys. Acta pmid:698234