Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 20

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Borthwick K et al. The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity. 2006 J. Biol. Chem. pmid:16908527
Bandyopadhyay GK et al. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. 2006 Diabetes pmid:16873691
Bell JA et al. Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA. 2006 Diabetologia pmid:16868746
Cheng D et al. Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes. 2007 Protein Expr. Purif. pmid:16854592
Neels JG and Olefsky JM Cell signaling. A new way to burn fat. 2006 Science pmid:16794069
Gu YG et al. Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors. 2006 J. Med. Chem. pmid:16789734
Pender C et al. Expression of genes regulating malonyl-CoA in human skeletal muscle. 2006 J. Cell. Biochem. pmid:16721829
Mao J et al. Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16717184
Wolfgang MJ and Lane MD Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system. 2006 Annu. Rev. Nutr. pmid:16704352
Oefner C et al. Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography. 2006 Acta Crystallogr. D Biol. Crystallogr. pmid:16699188
Wolfgang MJ et al. The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16651524
López M et al. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. 2006 Diabetes pmid:16644689
Ruderman NB and Saha AK Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A. 2006 Obesity (Silver Spring) pmid:16642960
Tang GL et al. Polyketide chain skipping mechanism in the biosynthesis of the hybrid nonribosomal peptide-polyketide antitumor antibiotic leinamycin in Streptomyces atroolivaceus S-140. 2006 J. Nat. Prod. pmid:16562841
Minkler PE et al. Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry. 2006 Anal. Biochem. pmid:16545769
Cheng JF et al. Synthesis and structure-activity relationship of small-molecule malonyl coenzyme A decarboxylase inhibitors. 2006 J. Med. Chem. pmid:16509570
Lindén D et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. 2006 FASEB J. pmid:16507761
Cahová M et al. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. 2007 Physiol Res pmid:16497094
Collier CA et al. Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16478780
Kuhl JE et al. Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16434556
Murase T et al. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. 2006 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:16410398
Beha A et al. Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16380389
Holloway GP et al. Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise. 2006 J. Physiol. (Lond.) pmid:16357012
Chiodi P et al. Tissue lipid accumulation by L-aminocarnitine, an inhibitor of carnitine-palmitoyltransferase-2. Studies in intact rats and isolated mitochondria. 1992 Biochim. Biophys. Acta pmid:1627637
Kelley DE Pulling in more fat. 2005 Cell Metab. pmid:16271525
McMillin JB et al. Evidence for malonyl-CoA-sensitive carnitine acyl-CoA transferase activity in sarcoplasmic reticulum of canine heart. 1992 J. Mol. Cell. Cardiol. pmid:1625348
Lane MD et al. Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure. 2005 Biochem. Soc. Trans. pmid:16246046
Kraegen EW et al. Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16234268
Dann HM and Drackley JK Carnitine palmitoyltransferase I in liver of periparturient dairy cows: effects of prepartum intake, postpartum induction of ketosis, and periparturient disorders. 2005 J. Dairy Sci. pmid:16230690
Hu Z et al. A role for hypothalamic malonyl-CoA in the control of food intake. 2005 J. Biol. Chem. pmid:16219771
Spiteller D et al. A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue. 2005 Angew. Chem. Int. Ed. Engl. pmid:16208728
Cha SH et al. Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16203972
Gambert S et al. Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. 2005 Biochim. Biophys. Acta pmid:16153888
Abu-Elheiga L et al. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16103361
Brusselmans K et al. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. 2005 Cancer Res. pmid:16061653
Neschen S et al. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. 2005 Cell Metab. pmid:16054099
Mizuarai S et al. Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. 2005 J. Biol. Chem. pmid:16027120
Lelliott CJ et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. 2005 FASEB J. pmid:15985534
Assifi MM et al. AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15956049
Mingrone G et al. Leptin pulsatility in formerly obese women. 2005 FASEB J. pmid:15955844
Dowell P et al. Monitoring energy balance: metabolites of fatty acid synthesis as hypothalamic sensors. 2005 Annu. Rev. Biochem. pmid:15952896
Kamoun P Valine is a precursor of propionyl-CoA. 1992 Trends Biochem. Sci. pmid:1595124
Nozu F et al. Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats. 1992 Hepatology pmid:1592350
Woldegiorgis G et al. Restoration of malonyl-CoA sensitivity of soluble rat liver mitochondria carnitine palmitoyltransferase by reconstitution with a partially purified malonyl-CoA binding protein. 1992 Arch. Biochem. Biophys. pmid:1586164
Kikuchi S et al. Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG. 1992 Arch. Biochem. Biophys. pmid:1586161
Giordano A et al. tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. 2005 Cell Death Differ. pmid:15846373
King KL et al. Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15821035
Griffin MJ and Sul HS Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c. 2004 IUBMB Life pmid:15814457
Planavila A et al. Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice. 2005 Biochem. Pharmacol. pmid:15794940
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815