Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Malonyl-coa

Download all related citations
Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Bian F et al. Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart. 2006 J. Mol. Cell. Cardiol. pmid:17020764
Bell JA et al. Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA. 2006 Diabetologia pmid:16868746
Borthwick K et al. The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity. 2006 J. Biol. Chem. pmid:16908527
Schujman GE et al. Structural basis of lipid biosynthesis regulation in Gram-positive bacteria. 2006 EMBO J. pmid:16932747
Lindén D et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. 2006 FASEB J. pmid:16507761
Wolfgang MJ and Lane MD The role of hypothalamic malonyl-CoA in energy homeostasis. 2006 J. Biol. Chem. pmid:17018521
Cha SH et al. Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:17030788
Bandyopadhyay GK et al. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. 2006 Diabetes pmid:16873691
Hayashi O and Satoh K Determination of acetyl-CoA and malonyl-CoA in germinating rice seeds using the LC-MS/MS technique. 2006 Biosci. Biotechnol. Biochem. pmid:17090944
Nolan CJ et al. Fatty acid signaling in the beta-cell and insulin secretion. 2006 Diabetes pmid:17130640
Ghadbane H et al. Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). 2007 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:17909282
Guay C et al. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. 2007 J. Biol. Chem. pmid:17928289
Thomson DM et al. LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17925454
Li S et al. Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase. 2007 J. Biol. Chem. pmid:17331946
López M et al. Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. 2007 Bioessays pmid:17295284
Abe T et al. Structure function analysis of benzalacetone synthase from Rheum palmatum. 2007 Bioorg. Med. Chem. Lett. pmid:17383877
Gao L et al. Simultaneous quantification of malonyl-CoA and several other short-chain acyl-CoAs in animal tissues by ion-pairing reversed-phase HPLC/MS. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17442642
Leonard E et al. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. 2007 Appl. Environ. Microbiol. pmid:17468269
López-Viñas E et al. Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A. 2007 J. Biol. Chem. pmid:17452323
Liu Y et al. Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. 2007 Assay Drug Dev Technol pmid:17477831
Wang X et al. Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. 2007 Anal. Biochem. pmid:17316539
Kadokawa H et al. Links between de novo fatty acid synthesis and leptin secretion in bovine adipocytes. 2007 J. Vet. Med. Sci. pmid:17409636
Noland RC et al. Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17638705
Gu L et al. GNAT-like strategy for polyketide chain initiation. 2007 Science pmid:17991863
Wolfgang MJ et al. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18032600
Ma SM et al. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. 2007 J. Am. Chem. Soc. pmid:17696354
Cheng D et al. Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes. 2007 Protein Expr. Purif. pmid:16854592
Cahová M et al. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. 2007 Physiol Res pmid:16497094
Folmes CD and Lopaschuk GD Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. 2007 Cardiovasc. Res. pmid:17126822
Guo W et al. Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17148751
Sebastián D et al. CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17062841
Szkudelski T Intracellular mediators in regulation of leptin secretion from adipocytes. 2007 Physiol Res pmid:17184148
Springob K et al. A polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones. 2007 FEBS J. pmid:17229146
Wallace DM et al. Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors. 2007 Bioorg. Med. Chem. Lett. pmid:17234415
Badaoui B et al. Goat acetyl-coenzyme A carboxylase alpha: molecular characterization, polymorphism, and association with milk traits. 2007 J. Dairy Sci. pmid:17235183
Harada N et al. Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice. 2007 Mol. Cell. Biol. pmid:17210641
Patil PB et al. Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. 2007 Arch. Physiol. Biochem. pmid:17522981
Minkler PE et al. Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. 2008 Anal. Biochem. pmid:18355435
Zhou L et al. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18083904
Sharma V et al. Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18203848
Wolfgang MJ and Lane MD Hypothalamic malonyl-coenzyme A and the control of energy balance. 2008 Mol. Endocrinol. pmid:18356287
Hayashi O and Satoh K Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. 2008 Biosci. Biotechnol. Biochem. pmid:18323644
Morash AJ et al. Intertissue regulation of carnitine palmitoyltransferase I (CPTI): mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss). 2008 Biochim. Biophys. Acta pmid:18359285
Saggerson D Malonyl-CoA, a key signaling molecule in mammalian cells. 2008 Annu. Rev. Nutr. pmid:18598135
Yatscoff MA et al. Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart. 2008 Pediatr. Res. pmid:18614968
Kerner J et al. Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation. 2008 Arch. Physiol. Biochem. pmid:18629681
Deshaies Y AMP kinase: heart, cancer and the CNS--view from the chair. 2008 Int J Obes (Lond) pmid:18719594
Lopaschuk GD AMP-activated protein kinase control of energy metabolism in the ischemic heart. 2008 Int J Obes (Lond) pmid:18719595
Lane MD et al. Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. 2008 Int J Obes (Lond) pmid:18719599
Wattanachaisaereekul S et al. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. 2008 Metab. Eng. pmid:18555717