Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Minkler PE et al. Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. 2008 Anal. Biochem. pmid:18355435
Zhou L et al. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18083904
Sharma V et al. Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18203848
Janovská A et al. AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. 2008 Mol. Cell. Endocrinol. pmid:18255222
Bortolami S et al. Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I. 2008 J. Bioenerg. Biomembr. pmid:18214656
Hayashi O and Satoh K Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. 2008 Biosci. Biotechnol. Biochem. pmid:18323644
Ussher JR and Lopaschuk GD The malonyl CoA axis as a potential target for treating ischaemic heart disease. 2008 Cardiovasc. Res. pmid:18499682
Kong R et al. Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis. 2008 J. Am. Chem. Soc. pmid:18529057
Saggerson D Malonyl-CoA, a key signaling molecule in mammalian cells. 2008 Annu. Rev. Nutr. pmid:18598135
Wattanachaisaereekul S et al. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. 2008 Metab. Eng. pmid:18555717
Tsfadia O et al. Pheromone biosynthetic pathways: PBAN-regulated rate-limiting steps and differential expression of desaturase genes in moth species. 2008 Insect Biochem. Mol. Biol. pmid:18405833
Singh SP et al. Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. 2008 Biochemistry pmid:18311940
Zhao Z et al. Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle. 2009 Life Sci. pmid:19250943
Katsuyama Y et al. Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. 2009 J. Biol. Chem. pmid:19258320
Lane MD and Cha SH Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. 2009 Biochem. Biophys. Res. Commun. pmid:19265677
Ide T et al. Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver. 2009 J. Nutr. Sci. Vitaminol. pmid:19352061
Celik A et al. Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia. 2009 Oncol. Rep. pmid:19288015
Relat J et al. A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme. 2009 FEBS J. pmid:19049515
Dean JT et al. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. 2009 Cell Metab. pmid:19490907
Downs SM et al. Fatty acid oxidation and meiotic resumption in mouse oocytes. 2009 Mol. Reprod. Dev. pmid:19455666
Tosin M et al. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. 2009 Chembiochem pmid:19507202
Cha SH and Lane MD Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway. 2009 Biochem. Biophys. Res. Commun. pmid:19523445
Metz JG et al. Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. 2009 Plant Physiol. Biochem. pmid:19272783
Nilsson LA et al. Prolactin suppresses malonyl-CoA concentration in human adipose tissue. 2009 Horm. Metab. Res. pmid:19551610
Miyanaga A and Horinouchi S Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases. 2009 J. Antibiot. pmid:19557027
Zha W et al. Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering. 2009 Metab. Eng. pmid:19558964
Awakawa T et al. Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. 2009 Chem. Biol. pmid:19549600
Eustáquio AS et al. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19590008
Kitazawa H et al. Development of a high-density assay for long-chain fatty acyl-CoA elongases. 2009 Lipids pmid:19575253
Fowler ZL et al. Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. 2009 Appl. Environ. Microbiol. pmid:19633125
Schink B An alternative to the glyoxylate shunt. 2009 Mol. Microbiol. pmid:19682245
Saez G et al. Gene expression and protein content in relation to intramuscular fat content in Muscovy and Pekin ducks. 2009 Poult. Sci. pmid:19834090
Ma SM et al. Complete reconstitution of a highly reducing iterative polyketide synthase. 2009 Science pmid:19900898
White JS Significance of differential effects of glucose and fructose on brain food signaling is uncertain. 2009 Biochem. Biophys. Res. Commun. pmid:19785993
Singh P et al. Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives. 2009 J Enzyme Inhib Med Chem pmid:18608763
Singh SP et al. Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE). 2009 Aging (Albany NY) pmid:20157589
Coletta DK et al. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. 2009 Diabetologia pmid:19169664
Ussher JR and Lopaschuk GD Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. 2009 Basic Res. Cardiol. pmid:19242641
Frøsig C et al. Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19190265
Lavarías S et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). 2009 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:19171199
Wang Q et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. 2009 Hepatology pmid:19177596
Kim DH et al. Molecular characterization of flavonoid malonyltransferase from Oryza sativa. 2009 Nov-Dec Plant Physiol. Biochem. pmid:19733090
Lopaschuk GD et al. Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite. 2010 Pharmacol. Rev. pmid:20392806
Maharjan S et al. Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides. 2010 Biotechnol. Lett. pmid:19838628
Kharel MK et al. Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. 2010 Org. Lett. pmid:20486694
Morash AJ et al. Genome duplication events have led to a diversification in the CPT I gene family in fish. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20519364
Thyfault JP et al. Metabolic profiling of muscle contraction in lean compared with obese rodents. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20504904
Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Hozyasz KK et al. Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate. 2010 Int J Oral Sci pmid:21125791
Tokutake Y et al. Coenzyme A and its thioester pools in fasted and fed rat tissues. 2010 Biochem. Biophys. Res. Commun. pmid:20933504