Malonyl-coa

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Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 20

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Zammit VA Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization. 1983 Biochem. J. pmid:6626153
Mills SE et al. Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I. 1983 Biochem. J. pmid:6615474
McGarry JD et al. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. 1983 Biochem. J. pmid:6615466
McGarry JD et al. Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA. 1978 J. Biol. Chem. pmid:659409
McCarthy AD and Hardie DG The multifunctional polypeptide chains of rabbit-mammary fatty-acid synthase. Stoichiometry of active sites and active-site mapping using limited proteolysis. 1983 Eur. J. Biochem. pmid:6549986
Trevisan CP et al. Myoglobinuria and carnitine palmityltransferase (CPT) deficiency: studies with malonyl-CoA suggest absence of only CPT-II. 1984 Neurology pmid:6538275
Cook GA Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. 1984 Biochem. J. pmid:6525169
Saggerson ED et al. Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation. 1984 Biochem. J. pmid:6508756
Kikuchi S and Kusaka T Purification of NADPH-dependent enoyl-CoA reductase involved in the malonyl-CoA dependent fatty acid elongation system of Mycobacterium smegmatis. 1984 J. Biochem. pmid:6501266
Yoshida S et al. Stereospecific incorporation of hydrogens from NADPH in elongation of very long fatty acyl-CoA by swine cerebral microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6497886
Fiol CJ and Bieber LL Sigmoid kinetics of purified beef heart mitochondrial carnitine palmitoyltransferase. Effect of pH and malonyl-CoA. 1984 J. Biol. Chem. pmid:6490647
Paulson DJ et al. Malonyl CoA inhibition of carnitine palmityltransferase in rat heart mitochondria. 1984 FEBS Lett. pmid:6489524
Bird MI and Saggerson ED Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity. 1984 Biochem. J. pmid:6487267
Cook GA Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in Ki values. 1984 J. Biol. Chem. pmid:6480597
Zammit VA et al. Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0 degree C and 37 degrees C with a fixed concentration of malonyl-CoA. 1984 Biochem. J. pmid:6477517
Mitzen EJ and Koeppen AH Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain. 1984 J. Neurochem. pmid:6429279
Cook GA et al. Altered sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA in ketotic diabetic rats. 1984 Biochem. J. pmid:6426472
Scholem RD and Brown GK Metabolism of malonic semialdehyde in man. 1983 Biochem. J. pmid:6418146
Rainwater DL and Kolattukudy PE Synthesis of mycocerosic acids from methylmalonyl coenzyme A by cell-free extracts of Mycobacterium tuberculosis var. bovis BCG. 1983 J. Biol. Chem. pmid:6402506
Kariya T and Wille LJ Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid). 1978 Biochem. Biophys. Res. Commun. pmid:637858
Prasad MR et al. Rat hepatic microsomal acetoacetyl-CoA reductase. A beta-ketoacyl-CoA reductase distinct from the long chain beta-ketoacyl-CoA reductase component of the microsomal fatty acid chain elongation system. 1984 J. Biol. Chem. pmid:6376489
Zammit VA Regulation of hepatic fatty acid oxidation and ketogenesis. 1983 Proc Nutr Soc pmid:6351086
Cook GA et al. Ketogenesis and malonyl coenzyme A content of isolated rat hepatocytes. 1978 J. Biol. Chem. pmid:632284
Fuller JQ and Leadlay PF Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water. 1983 Biochem. J. pmid:6311170
Leadlay PF and Fuller JQ Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. Studies with specifically tritiated (2R)-methylmalonyl-CoA as substrate. 1983 Biochem. J. pmid:6311169
Buckner JS et al. Synthesis of multimethyl-branched fatty acids by avian and mammalian fatty acid synthetase and its regulation by malonyl-CoA decarboxylase in the uropygial gland. 1978 Arch. Biochem. Biophys. pmid:629531
Murad S and Kishimoto Y Chain elongation of fatty acid in brain: a comparison of mitochondrial and microsomal enzyme activities. 1978 Arch. Biochem. Biophys. pmid:626498
McGarry JD and Foster DW Regulation of hepatic fatty acid oxidation and ketone body production. 1980 Annu. Rev. Biochem. pmid:6157353
Inui H et al. Fatty acid synthesis in mitochondria of Euglena gracilis. 1984 Eur. J. Biochem. pmid:6146525
Hunaiti AA and Kolattukudy PE Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus. 1984 Antimicrob. Agents Chemother. pmid:6143534
Beaty NB and Lane MD The polymerization of acetyl-CoA carboxylase. 1983 J. Biol. Chem. pmid:6138356
Ahmad PM and Ahmad F Effect of citrate on the different reactions catalyzed by rat mammary gland acetyl CoA carboxylase. 1983 Arch. Biochem. Biophys. pmid:6130749
Beynen AC et al. Acute effects of insulin on fatty acid metabolism in isolated rat hepatocytes. 1980 Horm. Metab. Res. pmid:6107268
Jones CT and Wahle KW Aspects of lipid metabolism in the foetal, neonatal and adult monogastric mammal. 1980 Biochem. Soc. Trans. pmid:6105107
Willard HF and Rosenberg LE Interactions of methylmalonyl CoA mutase from normal human fibroblasts with adenosylcobalamin and methylmalonyl CoA: evidence for non-equivalent active sites. 1980 Arch. Biochem. Biophys. pmid:6102452
Kim YS and Kolattukudy PE Stereospecificity of malonyl-CoA decarboxylase, acetyl-CoA carboxylase, and fatty acid synthetase from the uropygial gland of goose. 1980 J. Biol. Chem. pmid:6101330
Foster DW Banting lecture 1984. From glycogen to ketones--and back. 1984 Diabetes pmid:6094292
Beattie MA and Winder WW Mechanism of training-induced attenuation of postexercise ketosis. 1984 Am. J. Physiol. pmid:6093602
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008
Ludwig SA and Sprecher H Substrate specificity studies on the malonyl-CoA-dependent chain elongation of all-cis polyunsaturated fatty acids by rat liver microsomes. 1979 Arch. Biochem. Biophys. pmid:543721
Roughan PG et al. On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts. 1979 Biochem. J. pmid:534525
Bernert JT and Sprecher H Factors regulating the elongation of palmitic and stearic acid by rat liver microsomes. 1979 Biochim. Biophys. Acta pmid:476133
McGarry JD and Foster DW In support of the roles of malonyl-CoA and carnitine acyltransferase I in the regulation of hepatic fatty acid oxidation and ketogenesis. 1979 J. Biol. Chem. pmid:468816
Keyes SR et al. Rat liver microsomal elongation of fatty acids. Possible involvement of cytochrome b5. 1979 J. Biol. Chem. pmid:468787
Beynen AC et al. Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis. 1979 Diabetes pmid:467808
Bedord CJ et al. alpha-linolenic acid biosynthesis in Cyanidium caldarium. 1978 Arch. Biochem. Biophys. pmid:414660
Brady LJ et al. Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. 1985 Biochem. J. pmid:4091801
Brindle NP et al. Regulation of carnitine palmitoyltransferase activity by malonyl-CoA in mitochondria from sheep liver, a tissue with a low capacity for fatty acid synthesis. 1985 Biochem. J. pmid:4084227
Zammit VA and Corstorphine CG Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. 1985 Biochem. J. pmid:4062901
Mikkelsen J et al. Stoichiometry of substrate binding to rat liver fatty acid synthetase. 1985 Biochem. J. pmid:4052054
Zammit VA and Corstorphine CG Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states. 1985 Biochem. J. pmid:4052052
Edwards MR et al. Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites. 1985 Biochem. J. pmid:4052034
Bird MI and Saggerson ED Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase. 1985 Biochem. J. pmid:4052033
Otto DA et al. Reciprocal effects of 5-(tetradecyloxy)-2-furoic acid on fatty acid oxidation. 1985 Arch. Biochem. Biophys. pmid:4051503
Smith S et al. Modification of mammalian fatty acid synthetase activity by NADP. 1985 FEBS Lett. pmid:4043381
Ohashi K et al. Assay of fatty acid synthetase by mass fragmentography using [13C]malonyl-CoA. 1985 J. Biochem. pmid:4019438
Rahmatullah M et al. Mechanism of activation of bovine kidney pyruvate dehydrogenase a kinase by malonyl-CoA and enzyme-catalyzed decarboxylation of malonyl-CoA. 1985 Eur. J. Biochem. pmid:4018076
Agrawal VP and Stumpf PK Characterization and solubilization of an acyl chain elongation system in microsomes of leek epidermal cells. 1985 Arch. Biochem. Biophys. pmid:4015095
Koeppen AH et al. Fatty acid biosynthesis in Wallerian degeneration of rat sciatic nerve. 1979 Sep-Oct Muscle Nerve pmid:40126
Rose-Kahn G and Bar-Tana J Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in cultured rat hepatocytes. 1985 J. Biol. Chem. pmid:4008497
Mikkelsen J et al. Evidence that the medium-chain acyltransferase of lactating-goat mammary-gland fatty acid synthetase is identical with the acetyl/malonyltransferase. 1985 Biochem. J. pmid:4004809
Zierz S and Engel AG Regulatory properties of a mutant carnitine palmitoyltransferase in human skeletal muscle. 1985 Eur. J. Biochem. pmid:3996401
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Clouet P et al. High sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in liver of obese Zucker rats. 1985 FEBS Lett. pmid:3979557
Takamura Y et al. Malonyl-CoA: acetyl-CoA cycling. A new micromethod for determination of acyl-CoAs with malonate decarboxylase. 1985 Biochim. Biophys. Acta pmid:3978111
Bird MI et al. Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. 1985 Biochem. J. pmid:3977877
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Bremer J et al. Carnitine palmitoyltransferase. Activation by palmitoyl-CoA and inactivation by malonyl-CoA. 1985 Biochim. Biophys. Acta pmid:3967042
Peñas M and Benito M Regulation of carnitine palmitoyltransferase activity in the liver and brown adipose tissue in the newborn rat: effect of starvation and hypothermia. 1986 Biochem. Biophys. Res. Commun. pmid:3964261
Grantham BD and Zammit VA Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA. 1986 Biochem. J. pmid:3954755
Brady LJ et al. Hepatic mitochondrial inner-membrane properties, beta-oxidation and carnitine palmitoyltransferases A and B. Effects of genetic obesity and starvation. 1986 Biochem. J. pmid:3954744
Sire O et al. Preventive effect of clofibrate on carnitine palmitoyltransferase I inhibition and mitochondrial membrane phospholipid depletion induced by galactosamine. 1986 Biochim. Biophys. Acta pmid:3947665
Cassagne C et al. Fatty acid biosynthesis in the peripheral nervous system of normal and Trembler mice. 1986 Biochim. Biophys. Acta pmid:3947661
Mikkelsen J et al. Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase. 1985 Biochem. J. pmid:3922356
Anderson GJ and Kolattukudy PE Fatty acid chain elongation by microsomal enzymes from the bovine meibomian gland. 1985 Arch. Biochem. Biophys. pmid:3918501
Ravel D et al. Essential fatty acid interconversion during gestation in the rat. 1985 Biochim. Biophys. Acta pmid:3917686
Gamble MS and Cook GA Alteration of the apparent Ki of carnitine palmitoyltransferase for malonyl-CoA by the diabetic state and reversal by insulin. 1985 J. Biol. Chem. pmid:3894356
Rainwater DL and Kolattukudy PE Fatty acid biosynthesis in Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guérin. Purification and characterization of a novel fatty acid synthase, mycocerosic acid synthase, which elongates n-fatty acyl-CoA with methylmalonyl-CoA. 1985 J. Biol. Chem. pmid:3880746
Declercq PE et al. Interaction of malonyl-CoA and 2-tetradecylglycidyl-CoA with mitochondrial carnitine palmitoyltransferase I. 1985 J. Biol. Chem. pmid:3840167
Lund H Carnitine palmitoyltransferase: characterization of a labile detergent-extracted malonyl-CoA-sensitive enzyme from rat liver mitochondria. 1987 Biochim. Biophys. Acta pmid:3828368
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Mikkelsen J et al. A novel procedure for the preparation and characterization of catalytically active fatty acid synthetase immobilized on sepharose beads. 1987 J. Biol. Chem. pmid:3805043
Brady PS and Brady LJ Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. 1986 Biochem. J. pmid:3800962
Weinstein I et al. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. 1986 Biochem. J. pmid:3800903
Lloyd AC et al. Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. 1986 Biochem. J. pmid:3800884
Cook GA and Cox KA Hysteretic behaviour of carnitine palmitoyltransferase. The effect of preincubation with malonyl-CoA. 1986 Biochem. J. pmid:3790097
Robbins JE et al. Synthesis and NMR spectra of 13C-labeled coenzyme A esters. 1986 Anal. Biochem. pmid:3766971
Walters DW and Gilbert HF Thiol/disulfide redox equilibrium and kinetic behavior of chicken liver fatty acid synthase. 1986 J. Biol. Chem. pmid:3759951
Lund H and Woldegiorgis G Carnitine palmitoyltransferase: separation of enzyme activity and malonyl-CoA binding in rat liver mitochondria. 1986 Biochim. Biophys. Acta pmid:3756194
Bergseth S et al. Is carnitine palmitoyltransferase inhibited by a malonyl-CoA-binding unit in the mitochondria? 1986 Biochem. Soc. Trans. pmid:3743880
Oh-Hashi Y et al. Temperature- and growth-phase-dependent changes in membrane fatty acid compositions of Brevibacterium ammoniagenes. 1986 Arch. Biochem. Biophys. pmid:3729431
Prasad MR et al. Evidence for multiple condensing enzymes in rat hepatic microsomes catalyzing the condensation of saturated, monounsaturated, and polyunsaturated acyl coenzyme A. 1986 J. Biol. Chem. pmid:3722151
Trevisan CP et al. Malonyl-CoA abnormal inhibition of residual enzyme activity in carnitine palmitoyltransferase deficiency. 1986 Eur. Neurol. pmid:3720808
Lund H et al. Effects of thyroid state and fasting on the concentrations of CoA and malonyl-CoA in rat liver. 1986 Biochim. Biophys. Acta pmid:3707992
Bergseth S et al. Carnitine palmitoyltransferase: activation and inactivation in liver mitochondria from fed, fasted, hypo- and hyperthyroid rats. 1986 Biochim. Biophys. Acta pmid:3707984
Vary TC et al. A biochemical basis for depressed ketogenesis in sepsis. 1986 J Trauma pmid:3701891
Fiol CJ et al. Effect of malonyl-CoA on the kinetics and substrate cooperativity of membrane-bound carnitine palmitoyltransferase of rat heart mitochondria. 1987 Biochim. Biophys. Acta pmid:3689805
Takeshita M et al. Decrease of palmitoyl-CoA elongation in platelets and leukocytes in the patient of hereditary methemoglobinemia associated with mental retardation. 1987 Biochem. Biophys. Res. Commun. pmid:3675585
Henninger C et al. Effects of fenofibrate treatment on fatty acid oxidation in liver mitochondria of obese Zucker rats. 1987 Biochem. Pharmacol. pmid:3663237
Zierz S and Engel AG Different sites of inhibition of carnitine palmitoyltransferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle. 1987 Biochem. J. pmid:3663146