Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Swanson ST et al. Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues. 1998 Biochem. J. pmid:9794789
Saggerson ED and Carpenter CA The effect of malonyl-CoA on overt and latent carnitine acyltransferase activities in rat liver and adipocyte mitochondria. 1983 Biochem. J. pmid:6860313
Murthy MS and Pande SV Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes. 1987 Biochem. J. pmid:3435481
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Moir AM and Zammit VA Rapid switch of hepatic fatty acid metabolism from oxidation to esterification during diurnal feeding of meal-fed rats correlates with changes in the properties of acetyl-CoA carboxylase, but not of carnitine palmitoyltransferase I. 1993 Biochem. J. pmid:8097087
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Ghadiminejad I and Saggerson ED A study of properties and abundance of the components of liver carnitine palmitoyltransferases in mitochondrial inner and outer membranes. Effects of hypothyroidism, fasting and a ketotic diabetic state. 1991 Biochem. J. pmid:1872797
Bird MI and Saggerson ED Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase. 1985 Biochem. J. pmid:4052033
Edwards MR et al. Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites. 1985 Biochem. J. pmid:4052034
A'Bháird NN and Ramsay RR Malonyl-CoA inhibition of peroxisomal carnitine octanoyltransferase. 1992 Biochem. J. pmid:1530596
Kolodziej MP and Zammit VA Sensitivity of inhibition of rat liver mitochondrial outer-membrane carnitine palmitoyltransferase by malonyl-CoA to chemical- and temperature-induced changes in membrane fluidity. 1990 Biochem. J. pmid:2268270
McGarry JD et al. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. 1983 Biochem. J. pmid:6615466
Smith BK et al. Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. 2012 Biochem. J. pmid:22928974
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Baquet A et al. Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes. 1991 Biochem. J. pmid:1989589
Ramsay RR et al. Carnitine palmitoyltransferase in human erythrocyte membrane. Properties and malonyl-CoA sensitivity. 1991 Biochem. J. pmid:2039446
Civelek VN et al. Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP. 1996 Biochem. J. pmid:8809055
Ghadiminejad I and Saggerson ED The relationship of rat liver overt carnitine palmitoyltransferase to the mitochondrial malonyl-CoA binding entity and to the latent palmitoyltransferase. 1990 Biochem. J. pmid:2241911
Moir AM and Zammit VA Monitoring of changes in hepatic fatty acid and glycerolipid metabolism during the starved-to-fed transition in vivo. Studies on awake, unrestrained rats. 1993 Biochem. J. pmid:8424771
Buckley MG and Rath EA Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding. 1987 Biochem. J. pmid:2888457
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Leadlay PF and Fuller JQ Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. Studies with specifically tritiated (2R)-methylmalonyl-CoA as substrate. 1983 Biochem. J. pmid:6311169
Fuller JQ and Leadlay PF Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water. 1983 Biochem. J. pmid:6311170
Saggerson ED and Carpenter CA Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy. 1982 Biochem. J. pmid:7165725
Cook GA et al. Differential inhibition of ketogenesis by malonyl-CoA in mitochondria from fed and starved rats. 1980 Biochem. J. pmid:7236248
Ontko JA and Johns ML Evaluation of malonyl-CoA in the regulation of long-chain fatty acid oxidation in the liver. Evidence for an unidentified regulatory component of the system. 1980 Biochem. J. pmid:7236249
Kashfi K and Cook GA Proteinase treatment of intact hepatic mitochondria has differential effects on inhibition of carnitine palmitoyltransferase by different inhibitors. 1992 Biochem. J. pmid:1554374
Jones AV et al. Inhibition of plant fatty acid synthesis by nitroimidazoles. 1981 Biochem. J. pmid:7325993
Jordan BR and Harwood JL Fatty acid elongation by a particulate fraction from germinating pea. 1980 Biochem. J. pmid:7283974
Schofield PS et al. Altered interactions between lipogenesis and fatty acid oxidation in regenerating rat liver. 1987 Biochem. J. pmid:3593202
Zierz S and Engel AG Different sites of inhibition of carnitine palmitoyltransferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle. 1987 Biochem. J. pmid:3663146
Guzmán M et al. Flexibility of zonation of fatty acid oxidation in rat liver. 1995 Biochem. J. pmid:7487941
McGarry JD and Brown NF Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity. 2000 Biochem. J. pmid:10861226
Hamilton C and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes. 2000 Biochem. J. pmid:10926826
Roughan PG et al. On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts. 1979 Biochem. J. pmid:534525
Park EA et al. Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I. 1995 Biochem. J. pmid:7575418
Broadway NM and Saggerson ED Solubilization and separation of two distinct carnitine acyltransferases from hepatic microsomes: characterization of the malonyl-CoA-sensitive enzyme. 1995 Biochem. J. pmid:7575437
Mikkelsen J et al. Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase. 1985 Biochem. J. pmid:3922356
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Mikkelsen J et al. Evidence that the medium-chain acyltransferase of lactating-goat mammary-gland fatty acid synthetase is identical with the acetyl/malonyltransferase. 1985 Biochem. J. pmid:4004809
Bird MI et al. Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. 1985 Biochem. J. pmid:3977877
Mills SE et al. Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I. 1983 Biochem. J. pmid:6615474
Zammit VA Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization. 1983 Biochem. J. pmid:6626153
Zammit VA Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro. 1983 Biochem. J. pmid:6870813
Stephens TW et al. Effect of pH on malonyl-CoA inhibition of carnitine palmitoyltransferase I. 1983 Biochem. J. pmid:6882380
Cook GA et al. Malonyl-CoA inhibition of carnitine palmitoyltransferase: interpretation of I50 and K1 values. 1983 Biochem. J. pmid:6882381
Drynan L et al. The role of changes in the sensitivity of hepatic mitochondrial overt carnitine palmitoyltransferase in determining the onset of the ketosis of starvation in the rat. 1996 Biochem. J. pmid:8836117
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008