Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Hypothyroidism D007037 32 associated lipids
Insulin Resistance D007333 99 associated lipids
Ketosis D007662 13 associated lipids
Placental Insufficiency D010927 6 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Starvation D013217 47 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Myocardial Stunning D017682 10 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Swanson ST et al. Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues. 1998 Biochem. J. pmid:9794789
Murthy MS and Pande SV Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes. 1987 Biochem. J. pmid:3435481
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Moir AM and Zammit VA Rapid switch of hepatic fatty acid metabolism from oxidation to esterification during diurnal feeding of meal-fed rats correlates with changes in the properties of acetyl-CoA carboxylase, but not of carnitine palmitoyltransferase I. 1993 Biochem. J. pmid:8097087
Ghadiminejad I and Saggerson ED A study of properties and abundance of the components of liver carnitine palmitoyltransferases in mitochondrial inner and outer membranes. Effects of hypothyroidism, fasting and a ketotic diabetic state. 1991 Biochem. J. pmid:1872797
Bird MI and Saggerson ED Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase. 1985 Biochem. J. pmid:4052033
Edwards MR et al. Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites. 1985 Biochem. J. pmid:4052034
A'Bháird NN and Ramsay RR Malonyl-CoA inhibition of peroxisomal carnitine octanoyltransferase. 1992 Biochem. J. pmid:1530596
McGarry JD et al. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. 1983 Biochem. J. pmid:6615466
Civelek VN et al. Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP. 1996 Biochem. J. pmid:8809055
Moir AM and Zammit VA Monitoring of changes in hepatic fatty acid and glycerolipid metabolism during the starved-to-fed transition in vivo. Studies on awake, unrestrained rats. 1993 Biochem. J. pmid:8424771
Buckley MG and Rath EA Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding. 1987 Biochem. J. pmid:2888457
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Leadlay PF and Fuller JQ Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. Studies with specifically tritiated (2R)-methylmalonyl-CoA as substrate. 1983 Biochem. J. pmid:6311169
Fuller JQ and Leadlay PF Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water. 1983 Biochem. J. pmid:6311170
Cook GA et al. Differential inhibition of ketogenesis by malonyl-CoA in mitochondria from fed and starved rats. 1980 Biochem. J. pmid:7236248
Ontko JA and Johns ML Evaluation of malonyl-CoA in the regulation of long-chain fatty acid oxidation in the liver. Evidence for an unidentified regulatory component of the system. 1980 Biochem. J. pmid:7236249
Kashfi K and Cook GA Proteinase treatment of intact hepatic mitochondria has differential effects on inhibition of carnitine palmitoyltransferase by different inhibitors. 1992 Biochem. J. pmid:1554374
Jones AV et al. Inhibition of plant fatty acid synthesis by nitroimidazoles. 1981 Biochem. J. pmid:7325993
Jordan BR and Harwood JL Fatty acid elongation by a particulate fraction from germinating pea. 1980 Biochem. J. pmid:7283974
Zierz S and Engel AG Different sites of inhibition of carnitine palmitoyltransferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle. 1987 Biochem. J. pmid:3663146
Guzmán M et al. Flexibility of zonation of fatty acid oxidation in rat liver. 1995 Biochem. J. pmid:7487941
Hamilton C and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes. 2000 Biochem. J. pmid:10926826
Mikkelsen J et al. Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase. 1985 Biochem. J. pmid:3922356
Mikkelsen J et al. Evidence that the medium-chain acyltransferase of lactating-goat mammary-gland fatty acid synthetase is identical with the acetyl/malonyltransferase. 1985 Biochem. J. pmid:4004809
Mills SE et al. Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I. 1983 Biochem. J. pmid:6615474
Zammit VA Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization. 1983 Biochem. J. pmid:6626153
Zammit VA and Corstorphine CG Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states. 1985 Biochem. J. pmid:4052052
Stephens TW et al. Effect of pH on malonyl-CoA inhibition of carnitine palmitoyltransferase I. 1983 Biochem. J. pmid:6882380
Cook GA et al. Malonyl-CoA inhibition of carnitine palmitoyltransferase: interpretation of I50 and K1 values. 1983 Biochem. J. pmid:6882381
Drynan L et al. The role of changes in the sensitivity of hepatic mitochondrial overt carnitine palmitoyltransferase in determining the onset of the ketosis of starvation in the rat. 1996 Biochem. J. pmid:8836117
Henninger C et al. Effects of fenofibrate treatment on fatty acid oxidation in liver mitochondria of obese Zucker rats. 1987 Biochem. Pharmacol. pmid:3663237
Planavila A et al. Increased Akt protein expression is associated with decreased ceramide content in skeletal muscle of troglitazone-treated mice. 2005 Biochem. Pharmacol. pmid:15794940
Lilly K et al. Effect of etomoxiryl-CoA on different carnitine acyltransferases. 1992 Biochem. Pharmacol. pmid:1739421
Wahle KW et al. Biosynthesis of branched-chain fatty acids by preparations from bovine adipose tissue [proceedings]. 1978 Biochem. Soc. Trans. pmid:744376
Cook GA and Weakley LJ Effects of starvation on the carnitine palmitoyltransferase of hepatic peroxisomes. 1990 Biochem. Soc. Trans. pmid:2083787
Jones CT and Wahle KW Aspects of lipid metabolism in the foetal, neonatal and adult monogastric mammal. 1980 Biochem. Soc. Trans. pmid:6105107
Mynatt RL and Cook GA Modulation of the malonyl-CoA sensitivity of hepatic carnitine palmitoyltransferase (CPT) by phospholipids. 1994 Biochem. Soc. Trans. pmid:7958184
McGarry JD Travels with carnitine palmitoyltransferase I: from liver to germ cell with stops in between. 2001 Biochem. Soc. Trans. pmid:11356162
Eaton S et al. Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux. 2001 Biochem. Soc. Trans. pmid:11356163
Jiffri E et al. Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat. 1996 Biochem. Soc. Trans. pmid:8736922
Broadway NM et al. Microsomal malonyl-CoA-sensitive carnitine acyltransferase. 2001 Biochem. Soc. Trans. pmid:11356165
Zammit VA et al. Structure-function relationships of the liver and muscle isoforms of carnitine palmitoyltransferase I. 2001 Biochem. Soc. Trans. pmid:11356169
Hegardt FG et al. Post-transcriptional regulation of rat carnitine octanoyltransferase. 2001 Biochem. Soc. Trans. pmid:11356174
Fraser F et al. Evidence that both the acyl-CoA- and malonyl-CoA binding sites of mitochondrial overt carnitine palmitoyltransferase (CPT I) are exposed on the cytosolic face of the outer membrane. 1996 Biochem. Soc. Trans. pmid:8736842
Lane MD et al. Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure. 2005 Biochem. Soc. Trans. pmid:16246046
Ruderman NB et al. Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. 2003 Biochem. Soc. Trans. pmid:12546685
Hopkins TA et al. AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart. 2003 Biochem. Soc. Trans. pmid:12546686
Bergseth S et al. Is carnitine palmitoyltransferase inhibited by a malonyl-CoA-binding unit in the mitochondria? 1986 Biochem. Soc. Trans. pmid:3743880
Frayn KN The glucose-fatty acid cycle: a physiological perspective. 2003 Biochem. Soc. Trans. pmid:14641007