Malonyl-coa

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Kudej RK et al. Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. 2011 Cardiovasc. Res. pmid:21835931
Folmes CD and Lopaschuk GD Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. 2007 Cardiovasc. Res. pmid:17126822
Ussher JR and Lopaschuk GD The malonyl CoA axis as a potential target for treating ischaemic heart disease. 2008 Cardiovasc. Res. pmid:18499682
Ussher JR et al. Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. 2012 Cardiovasc. Res. pmid:22436846
Zhabyeyev P et al. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. 2013 Cardiovasc. Res. pmid:23257023
Mercier R et al. Excess membrane synthesis drives a primitive mode of cell proliferation. 2013 Cell pmid:23452849
Unger RH The hyperleptinemia of obesity-regulator of caloric surpluses. 2004 Cell pmid:15084251
Giordano A et al. tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. 2005 Cell Death Differ. pmid:15846373
Dean JT et al. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. 2009 Cell Metab. pmid:19490907
Kelley DE Pulling in more fat. 2005 Cell Metab. pmid:16271525
Neschen S et al. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. 2005 Cell Metab. pmid:16054099
López M et al. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. 2008 Cell Metab. pmid:18460330
Zammit VA and Arduini A The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. 2008 Cell Metab. pmid:18762014
Zhang S and Kim KH Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. 1998 Cell. Signal. pmid:9502115
Awakawa T et al. Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. 2009 Chem. Biol. pmid:19549600
Zhou P et al. Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. 1999 Chem. Biol. pmid:10421763
Matharu AL et al. MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor. 1998 Chem. Biol. pmid:9862793
Jensen K et al. Polyketide proofreading by an acyltransferase-like enzyme. 2012 Chem. Biol. pmid:22444588
Kage H et al. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. 2013 Chem. Biol. pmid:23790487
Ellis JM and Wolfgang MJ A genetically encoded metabolite sensor for malonyl-CoA. 2012 Chem. Biol. pmid:23102226
Hitchman TS et al. Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. 1998 Chem. Biol. pmid:9479478
Hamed RB et al. Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. 2010 Chem. Commun. (Camb.) pmid:20162132
Tosin M et al. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. 2009 Chembiochem pmid:19507202
Musiol EM et al. The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. 2013 Chembiochem pmid:23828654
Awakawa T et al. 4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. 2013 Chembiochem pmid:23609937
Kantor PF et al. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. 2000 Circ. Res. pmid:10720420
Zordoky BN et al. AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation. 2014 Circ. Res. pmid:25001074
Lewandowski ED et al. Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. 2013 Circ. Res. pmid:22982985
Kolwicz SC et al. Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. 2012 Circ. Res. pmid:22730442
Dyck JR et al. Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. 2004 Circ. Res. pmid:15105298
Dagher Z et al. Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. 2001 Circ. Res. pmid:11420304
Goodman SI et al. Methylmalonic/beta-hydroxy-n-valeric aciduria due to methylmalonyl-CoA mutase deficiency. 1978 Clin. Chim. Acta pmid:28187
Wen J and Kerr RG Purification and characterization of the fatty acid synthase from Bugula neritina. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11250539
Gutières S et al. Cloning and tissue distribution of a carnitine palmitoyltransferase I gene in rainbow trout (Oncorhynchus mykiss). 2003 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:12781981
Lavarías S et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). 2009 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:19171199
McGrath RP Unusual case of metabolic acidosis. 1989 Crit. Care Med. pmid:2909311
Schujman GE et al. FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. 2003 Dev. Cell pmid:12737802
Chen S et al. More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling. 1994 Diabetes pmid:8013751
Ido Y et al. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. 2002 Diabetes pmid:11756336
Roduit R et al. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. 2004 Diabetes pmid:15047616
Herrero L et al. Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion. 2005 Diabetes pmid:15677504
Prentki M et al. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. 2002 Diabetes pmid:12475783
Bandyopadhyay GK et al. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. 2006 Diabetes pmid:16873691
Nolan CJ et al. Fatty acid signaling in the beta-cell and insulin secretion. 2006 Diabetes pmid:17130640
López M et al. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. 2006 Diabetes pmid:16644689
McGarry JD and Foster DW Effects of exogenous fatty acid concentration on glucagon-induced changes in hepatic fatty acid metabolism. 1980 Diabetes pmid:7380110
BÃ¥venholm PN et al. Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. 2000 Diabetes pmid:10909961
Dean D et al. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. 2000 Diabetes pmid:10923628
Oakes ND et al. Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. 1997 Diabetes pmid:9392490
Go Y et al. Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis. 2016 Diabetes pmid:27385159