Malonyl-coa

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Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Morishima N and Ikai A Active site organization of bacterial type I fatty acid synthetase. 1987 J. Biochem. pmid:3448090
Watanabe K et al. Fatty acid synthesis of an eicosapentaenoic acid-producing bacterium: de novo synthesis, chain elongation, and desaturation systems. 1997 J. Biochem. pmid:9378728
Ohashi K et al. Assay of fatty acid synthetase by mass fragmentography using [13C]malonyl-CoA. 1985 J. Biochem. pmid:4019438
Saito K et al. Steric course of deuterium incorporation from [2-2H2]malonyl-CoA into fatty acids by fatty acid synthetases. 1981 J. Biochem. pmid:7037760
Kikuchi S and Kusaka T New malonyl-CoA-dependent fatty acid elongation system in Mycobacterium smegmatis. 1982 J. Biochem. pmid:7142122
Kawaguchi A et al. Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. 1980 J. Biochem. pmid:7419496
Bao W et al. The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. 1999 J. Bacteriol. pmid:10419974
Takagi M et al. Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus. 2010 J. Bacteriol. pmid:19854913
Smith AC and Cronan JE Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo. 2012 J. Bacteriol. pmid:22037404
Menendez C et al. Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation. 1999 J. Bacteriol. pmid:9973333
Furukawa H et al. Thiolactomycin resistance in Escherichia coli is associated with the multidrug resistance efflux pump encoded by emrAB. 1993 J. Bacteriol. pmid:8509326
Hügler M et al. Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO(2) fixation. 2002 J. Bacteriol. pmid:11948153
Thompson TE and Zeikus JG Regulation of carbon and electron flow in Propionispira arboris: relationship of catabolic enzyme levels to carbon substrates fermented during propionate formation via the methylmalonyl coenzyme A pathway. 1988 J. Bacteriol. pmid:3410821
Jackowski S and Rock CO Consequences of reduced intracellular coenzyme A content in Escherichia coli. 1986 J. Bacteriol. pmid:3519582
Revill WP et al. Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. 1995 J. Bacteriol. pmid:7608065
Elayan IM and Winder WW Effect of glucose infusion on muscle malonyl-CoA during exercise. 1991 J. Appl. Physiol. pmid:2055826
Duan C and Winder WW Control of malonyl-CoA by glucose and insulin in perfused skeletal muscle. 1993 J. Appl. Physiol. pmid:8335589
Winder WW et al. Effect of adrenodemedullation on decline in muscle malonyl-CoA during exercise. 1993 J. Appl. Physiol. pmid:8335590
Winder WW et al. Muscle malonyl-CoA decreases during exercise. 1989 J. Appl. Physiol. pmid:2558099
Park SH et al. Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle. 2002 J. Appl. Physiol. pmid:12433937
Odland LM et al. Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise. 2000 J. Appl. Physiol. pmid:11090589
Winder WW and Holmes BF Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated. 2000 J. Appl. Physiol. pmid:11090599
Maclean PS and Winder WW Caffeine decreases malonyl-CoA in isolated perfused skeletal muscle of rats. 1995 J. Appl. Physiol. pmid:7615461
Rasmussen BB et al. Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase. 1998 J. Appl. Physiol. pmid:9804562
Merrill GF et al. Influence of malonyl-CoA and palmitate concentration on rate of palmitate oxidation in rat muscle. 1998 J. Appl. Physiol. pmid:9804598
Rasmussen BB and Winder WW Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. 1997 J. Appl. Physiol. pmid:9338417
Duan C and Winder WW Nerve stimulation decreases malonyl-CoA in skeletal muscle. 1992 J. Appl. Physiol. pmid:1349012
Hutber CA et al. Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise. 1997 J. Appl. Physiol. pmid:9390963
McCormack JG et al. Effects of ranolazine on oxidative substrate preference in epitrochlearis muscle. 1996 J. Appl. Physiol. pmid:8872662
Kimber NE et al. Skeletal muscle fat metabolism after exercise in humans: influence of fat availability. 2013 J. Appl. Physiol. pmid:23519231
Miyanaga A and Horinouchi S Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases. 2009 J. Antibiot. pmid:19557027
Wang IK et al. Use of carbon-13 in biosynthetic studies: origin of the malonyl coenzyme A incorporated into tetracycline by Streptomyces aureofaciens. 1986 J. Antibiot. pmid:3096928
Ma SM et al. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. 2007 J. Am. Chem. Soc. pmid:17696354
Jeong JC et al. Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation. 2005 J. Am. Chem. Soc. pmid:15631450
Abe I et al. A plant type III polyketide synthase that produces pentaketide chromone. 2005 J. Am. Chem. Soc. pmid:15686354
Kong R et al. Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis. 2008 J. Am. Chem. Soc. pmid:18529057
Mo S et al. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. 2011 J. Am. Chem. Soc. pmid:21175203
Vary TC et al. A biochemical basis for depressed ketogenesis in sepsis. 1986 J Trauma pmid:3701891
Singh P et al. Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives. 2009 J Enzyme Inhib Med Chem pmid:18608763
Griffin MJ and Sul HS Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c. 2004 IUBMB Life pmid:15814457
Dulloo AG et al. Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity. 2004 Int. J. Obes. Relat. Metab. Disord. pmid:15592483
Wang F et al. Inhibitive effect of zinc ion on fatty acid synthase from chicken liver. 2003 Int. J. Biochem. Cell Biol. pmid:12531252
Hozyasz KK et al. Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate. 2010 Int J Oral Sci pmid:21125791
Deshaies Y AMP kinase: heart, cancer and the CNS--view from the chair. 2008 Int J Obes (Lond) pmid:18719594
Lopaschuk GD AMP-activated protein kinase control of energy metabolism in the ischemic heart. 2008 Int J Obes (Lond) pmid:18719595
Lane MD et al. Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. 2008 Int J Obes (Lond) pmid:18719599
Lehmann D et al. Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features. 2017 Int J Mol Sci pmid:28054946
Guertl B et al. Metabolic cardiomyopathies. 2000 Int J Exp Pathol pmid:11298185
Tsfadia O et al. Pheromone biosynthetic pathways: PBAN-regulated rate-limiting steps and differential expression of desaturase genes in moth species. 2008 Insect Biochem. Mol. Biol. pmid:18405833
Nilsson LA et al. Prolactin suppresses malonyl-CoA concentration in human adipose tissue. 2009 Horm. Metab. Res. pmid:19551610
Sugden MC et al. Hyperthyroidism facilitates cardiac fatty acid oxidation through altered regulation of cardiac carnitine palmitoyltransferase: studies in vivo and with cardiac myocytes. 1999 Horm. Metab. Res. pmid:10422724
Beynen AC et al. Acute effects of insulin on fatty acid metabolism in isolated rat hepatocytes. 1980 Horm. Metab. Res. pmid:6107268
Nozu F et al. Changes of hepatic fatty acid metabolism produced by chronic thioacetamide administration in rats. 1992 Hepatology pmid:1592350
Wang Q et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. 2009 Hepatology pmid:19177596
Zhang YQ et al. Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans. 2004 Genetics pmid:15514053
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112
Jahnke LL and Diggs K Evidence for the synthesis of the multi-positional isomers of monounsaturated fatty acid in Methylococcus capsusatus by the anaerobic pathway. 1989 FEMS Microbiol. Lett. pmid:11542184
Cassagne C et al. Evidence of alkane synthesis by the sciatic nerve of the rabbit. 1977 FEBS Lett. pmid:913574
Ghadiminejad I and Saggerson ED Carnitine palmitoyltransferase (CPT2) from liver mitochondrial inner membrane becomes inhibitable by malonyl-CoA if reconstituted with outer membrane malonyl-CoA binding protein. 1990 FEBS Lett. pmid:2401367
Velasco G et al. Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components. 1998 FEBS Lett. pmid:9845345
Saggerson ED and Carpenter CA Effects of fasting and malonyl CoA on the kinetics of carnitine palmitoyltransferase and carnitine octanoyltransferase in intact rat liver mitochondria. 1981 FEBS Lett. pmid:7297689
Paulson DJ et al. Malonyl CoA inhibition of carnitine palmityltransferase in rat heart mitochondria. 1984 FEBS Lett. pmid:6489524
Broadway NM and Saggerson ED Inhibition of liver microsomal carnitine acyltransferases by sulphonylurea drugs. 1995 FEBS Lett. pmid:7672113
Engeser H et al. Localization of three non-thiol binding sites on polypeptide chain beta of yeast fatty acid synthetase. 1977 FEBS Lett. pmid:334565
Kurosaki F Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts. 1996 FEBS Lett. pmid:8566239
Abe I et al. The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide. 2004 FEBS Lett. pmid:15044020
Scholte HR et al. The source of malonyl-CoA in rat heart. The calcium paradox releases acetyl-CoA carboxylase and not propionyl-CoA carboxylase. 1986 FEBS Lett. pmid:2869975
Saggerson ED and Carpenter CA Malonyl CoA inhibition of carnitine acyltransferase activities: effects of thiol-group reagents. 1982 FEBS Lett. pmid:7067817
Saggerson ED and Carpenter CA Effects of fasting, adrenalectomy and streptozotocin-diabetes on sensitivity of hepatic carnitine acyltransferase to malonyl CoA. 1981 FEBS Lett. pmid:7286215
Saggerson ED and Carpenter CA Carnitine palmitoyltransferase and carnitine octanoyltransferase activities in liver, kidney cortex, adipocyte, lactating mammary gland, skeletal muscle and heart. 1981 FEBS Lett. pmid:7286216
Morillas M et al. Identification of the two histidine residues responsible for the inhibition by malonyl-CoA in peroxisomal carnitine octanoyltransferase from rat liver. 2000 FEBS Lett. pmid:10648838
Saggerson ED and Carpenter CA Regulation of hepatic carnitine palmitoyltransferase activity during the foetal-neonatal transition. 1982 FEBS Lett. pmid:7160469
Bessoule JJ et al. Fatty acid synthesis in mitochondria from Saccharomyces cerevisiae. 1987 FEBS Lett. pmid:3552725
Hoffmann A and Dimroth P Stereochemistry of the methylmalonyl-CoA decarboxylation reaction. 1987 FEBS Lett. pmid:3609308
Haydock SF et al. Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases. 1995 FEBS Lett. pmid:7589545
Naganuma T et al. Biochemical characterization of the very long-chain fatty acid elongase ELOVL7. 2011 FEBS Lett. pmid:21959040
Clouet P et al. High sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in liver of obese Zucker rats. 1985 FEBS Lett. pmid:3979557
Smith S et al. Modification of mammalian fatty acid synthetase activity by NADP. 1985 FEBS Lett. pmid:4043381
Saggerson ED and Topping DL Glycerolphosphate acyltransferase, dihydroxyacetonephosphate acyltransferase and carnitine palmitoyltransferase in a glycogen storage disease (gsd/gsd) rat. 1981 FEBS Lett. pmid:6946003
Wolkowicz PE and Wood JM Effect of malonyl-CoA on calcium uptake and pyridine nucleotide redox state in rat liver mitochondria. 1979 FEBS Lett. pmid:221253
Pageaux JF et al. [Rapid induction of hepatic acetyl-CoA carboxylase activity after estradiol benzoate injection in the quail]. 1981 FEBS Lett. pmid:9222334
Relat J et al. A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme. 2009 FEBS J. pmid:19049515
Springob K et al. A polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones. 2007 FEBS J. pmid:17229146
Wolfgang MJ and Lane MD Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity. 2011 FEBS J. pmid:21199367
Jenei ZA et al. Packing of transmembrane domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and malonyl-CoA sensitivity of the mitochondrial outer membrane protein. 2011 FASEB J. pmid:21917985
Mingrone G et al. Leptin pulsatility in formerly obese women. 2005 FASEB J. pmid:15955844
Lelliott CJ et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. 2005 FASEB J. pmid:15985534
Lindén D et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. 2006 FASEB J. pmid:16507761
Winder WW Malonyl-CoA--regulator of fatty acid oxidation in muscle during exercise. 1998 Exerc Sport Sci Rev pmid:9696987
Trevisan CP et al. Malonyl-CoA abnormal inhibition of residual enzyme activity in carnitine palmitoyltransferase deficiency. 1986 Eur. Neurol. pmid:3720808
Schönekess BO et al. Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency. 1995 Eur. J. Pharmacol. pmid:8605952
Domergue F et al. Evidence that oleoyl-CoA and ATP-dependent elongations coexist in rapeseed (Brassica napus L.). 1999 Eur. J. Biochem. pmid:10406955
Inui H et al. Fatty acid synthesis in mitochondria of Euglena gracilis. 1984 Eur. J. Biochem. pmid:6146525
Trumble GE et al. Purification and characterization of rat skeletal muscle acetyl-CoA carboxylase. 1995 Eur. J. Biochem. pmid:7628470
Morita H et al. Novel polyketides synthesized with a higher plant stilbene synthase. 2001 Eur. J. Biochem. pmid:11432743
Wölfle K et al. On the mechanism of action of methylmalonyl-CoA mutase. Change of the steric course on isotope substitution. 1986 Eur. J. Biochem. pmid:2870921
Hügler M et al. Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. 2003 Eur. J. Biochem. pmid:12581213
Rahmatullah M et al. Mechanism of activation of bovine kidney pyruvate dehydrogenase a kinase by malonyl-CoA and enzyme-catalyzed decarboxylation of malonyl-CoA. 1985 Eur. J. Biochem. pmid:4018076
Prip-Buus C et al. Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells. 1992 Eur. J. Biochem. pmid:1356769
Kresze GB et al. Reaction of yeast fatty acid synthetase with iodoacetamide. 3. Malonyl-coenzyme A decarboxylase as product of the reaction of fatty acid synthetase with iodoacetamide. 1977 Eur. J. Biochem. pmid:334544