Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Lane MD and Cha SH Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. 2009 Biochem. Biophys. Res. Commun. pmid:19265677
Rutkoski A and Jaworski JG Fatty acid synthetase from chloroplasts of soybean cotyledons: ACP activation and CoA inhibition. 1978 Biochem. Biophys. Res. Commun. pmid:718691
Cha SH and Lane MD Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway. 2009 Biochem. Biophys. Res. Commun. pmid:19523445
Takeshita M et al. Decrease of palmitoyl-CoA elongation in platelets and leukocytes in the patient of hereditary methemoglobinemia associated with mental retardation. 1987 Biochem. Biophys. Res. Commun. pmid:3675585
White JS Significance of differential effects of glucose and fructose on brain food signaling is uncertain. 2009 Biochem. Biophys. Res. Commun. pmid:19785993
Kashfi K et al. Effects of cholesterol loading of mouse macrophages on carnitine palmitoyltransferase activity and sensitivity to inhibition by malonyl-CoA. 1991 Biochem. Biophys. Res. Commun. pmid:2059202
Thupari JN et al. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. 2001 Biochem. Biophys. Res. Commun. pmid:11444828
Eaton S et al. Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. 2001 Biochem. Biophys. Res. Commun. pmid:11444876
Kashfi K and Cook GA Malonyl-CoA inhibits proteolysis of carnitine palmitoyltransferase. 1991 Biochem. Biophys. Res. Commun. pmid:1859420
Oguro S et al. Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. 2004 Biochem. Biophys. Res. Commun. pmid:15530429
Nicot C et al. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. 2004 Biochem. Biophys. Res. Commun. pmid:15541339
Saito K et al. Differential hydrogen exchange during the fatty acid synthetase reaction: deuterium distribution of fatty acids synthesized from [2-2H2]malonyl-CoA. 1982 Biochem. Biophys. Res. Commun. pmid:6758778
Saha AK et al. AMPK regulation of the growth of cultured human keratinocytes. 2006 Biochem. Biophys. Res. Commun. pmid:16949049
Srinivasan KR and Kumar S Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis. 1981 Biochem. Biophys. Res. Commun. pmid:7247949
Knudsen J and Grunnet I Primer specificity of mammalian mammary gland fatty acid synthetases. 1980 Biochem. Biophys. Res. Commun. pmid:7417345
Guzmán M et al. Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA. 1987 Biochem. Biophys. Res. Commun. pmid:3426584
Suh DY et al. Evidence for catalytic cysteine-histidine dyad in chalcone synthase. 2000 Biochem. Biophys. Res. Commun. pmid:10973790
Abo-Hashema KA et al. Liver mitochondria, confirmed as intact by complete suppression of succinate uptake and oxidation, possess a carnitine palmitoyltransferase I that is totally inhibited by malonyl CoA. 1999 Biochem. Biophys. Res. Commun. pmid:10329463
Iio W et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. 2012 Biochem. Biophys. Res. Commun. pmid:22503976
Peñas M and Benito M Regulation of carnitine palmitoyltransferase activity in the liver and brown adipose tissue in the newborn rat: effect of starvation and hypothermia. 1986 Biochem. Biophys. Res. Commun. pmid:3964261
Nagi MN et al. Evidence for two separate beta-ketoacyl CoA reductase components of the hepatic microsomal fatty acid chain elongation system in the rat. 1989 Biochem. Biophys. Res. Commun. pmid:2692567
Saha AK et al. Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. 2004 Biochem. Biophys. Res. Commun. pmid:14733947
Luthria DL et al. Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. 1997 Biochem. Biophys. Res. Commun. pmid:9144553
Tokutake Y et al. Coenzyme A and its thioester pools in fasted and fed rat tissues. 2010 Biochem. Biophys. Res. Commun. pmid:20933504
Kariya T and Wille LJ Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid). 1978 Biochem. Biophys. Res. Commun. pmid:637858
Moir AM and Zammit VA Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume. 1995 Biochem. J. pmid:7848296
Murthy MS and Pande SV Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes. 1987 Biochem. J. pmid:3435481
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Zammit VA Regulation of hepatic fatty acid metabolism. The activities of mitochondrial and microsomal acyl-CoA:sn-glycerol 3-phosphate O-acyltransferase and the concentrations of malonyl-CoA, non-esterified and esterified carnitine, glycerol 3-phosphate, ketone bodies and long-chain acyl-CoA esters in livers of fed or starved pregnant, lactating and weaned rats. 1981 Biochem. J. pmid:7326003
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Moir AM and Zammit VA Rapid switch of hepatic fatty acid metabolism from oxidation to esterification during diurnal feeding of meal-fed rats correlates with changes in the properties of acetyl-CoA carboxylase, but not of carnitine palmitoyltransferase I. 1993 Biochem. J. pmid:8097087
Niot I et al. Involvement of microsomal vesicles in part of the sensitivity of carnitine palmitoyltransferase I to malonyl-CoA inhibition in mitochondrial fractions of rat liver. 1994 Biochem. J. pmid:7998995
Scholem RD and Brown GK Metabolism of malonic semialdehyde in man. 1983 Biochem. J. pmid:6418146
Awan MM and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation. 1993 Biochem. J. pmid:8216240
Mynatt RL et al. Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids. 1994 Biochem. J. pmid:8192665
Edwards MR et al. Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites. 1985 Biochem. J. pmid:4052034
Mikkelsen J et al. Stoichiometry of substrate binding to rat liver fatty acid synthetase. 1985 Biochem. J. pmid:4052054
Walker TA et al. Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris. 1981 Biochem. J. pmid:6803763
Zammit VA Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA. 1984 Biochem. J. pmid:6712621
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Jones AV et al. Inhibition of plant fatty acid synthesis by nitroimidazoles. 1981 Biochem. J. pmid:7325993
Walker KA et al. Fluazifop, a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. 1988 Biochem. J. pmid:2902848
Grantham BD and Zammit VA Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes. 1988 Biochem. J. pmid:3277623
Brindle NP et al. Regulation of carnitine palmitoyltransferase activity by malonyl-CoA in mitochondria from sheep liver, a tissue with a low capacity for fatty acid synthesis. 1985 Biochem. J. pmid:4084227
McCormick K et al. Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation. 1983 Biochem. J. pmid:6661211
Zammit VA and Corstorphine CG Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states. 1985 Biochem. J. pmid:4052052
Zammit VA and Corstorphine CG Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. 1985 Biochem. J. pmid:4062901
Sanchez J and Harwood JL Products of fatty acid synthesis by a particulate fraction from germinating pea (Pisum sativum L.). 1981 Biochem. J. pmid:7337704
Pégorier JP et al. Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols. 1988 Biochem. J. pmid:3355499
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497