Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Body Weight D001835 333 associated lipids
Cleft Lip D002971 8 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
López-Viñas E et al. Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A. 2007 J. Biol. Chem. pmid:17452323
Leonard E et al. Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. 2007 Appl. Environ. Microbiol. pmid:17468269
Liu Y et al. Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. 2007 Assay Drug Dev Technol pmid:17477831
Patil PB et al. Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. 2007 Arch. Physiol. Biochem. pmid:17522981
Noland RC et al. Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17638705
Ma SM et al. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. 2007 J. Am. Chem. Soc. pmid:17696354
Ghadbane H et al. Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). 2007 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:17909282
Thomson DM et al. LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17925454
Guay C et al. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. 2007 J. Biol. Chem. pmid:17928289
Gu L et al. GNAT-like strategy for polyketide chain initiation. 2007 Science pmid:17991863
Wolfgang MJ et al. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18032600
Zhou L et al. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18083904
Sharma V et al. Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18203848
Bortolami S et al. Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I. 2008 J. Bioenerg. Biomembr. pmid:18214656
Janovská A et al. AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. 2008 Mol. Cell. Endocrinol. pmid:18255222
Singh SP et al. Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. 2008 Biochemistry pmid:18311940
Hayashi O and Satoh K Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. 2008 Biosci. Biotechnol. Biochem. pmid:18323644
Minkler PE et al. Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. 2008 Anal. Biochem. pmid:18355435
Wolfgang MJ and Lane MD Hypothalamic malonyl-coenzyme A and the control of energy balance. 2008 Mol. Endocrinol. pmid:18356287
Morash AJ et al. Intertissue regulation of carnitine palmitoyltransferase I (CPTI): mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss). 2008 Biochim. Biophys. Acta pmid:18359285
Funabashi M et al. Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus. 2008 J. Biol. Chem. pmid:18364359
Schujman GE et al. A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism. 2008 Mol. Microbiol. pmid:18384517
Tsfadia O et al. Pheromone biosynthetic pathways: PBAN-regulated rate-limiting steps and differential expression of desaturase genes in moth species. 2008 Insect Biochem. Mol. Biol. pmid:18405833
López M et al. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. 2008 Cell Metab. pmid:18460330
Ussher JR and Lopaschuk GD The malonyl CoA axis as a potential target for treating ischaemic heart disease. 2008 Cardiovasc. Res. pmid:18499682
Kong R et al. Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis. 2008 J. Am. Chem. Soc. pmid:18529057
Wattanachaisaereekul S et al. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. 2008 Metab. Eng. pmid:18555717
Kashfi K and Cook GA Malonyl-CoA inhibits proteolysis of carnitine palmitoyltransferase. 1991 Biochem. Biophys. Res. Commun. pmid:1859420
Saggerson D Malonyl-CoA, a key signaling molecule in mammalian cells. 2008 Annu. Rev. Nutr. pmid:18598135
Singh P et al. Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives. 2009 J Enzyme Inhib Med Chem pmid:18608763
Yatscoff MA et al. Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart. 2008 Pediatr. Res. pmid:18614968
Pénicaud L et al. Effect of insulin on the properties of liver carnitine palmitoyltransferase in the starved rat: assessment by the euglycemic hyperinsulinemic clamp. 1991 Metab. Clin. Exp. pmid:1861636
Kerner J et al. Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation. 2008 Arch. Physiol. Biochem. pmid:18629681
Deshaies Y AMP kinase: heart, cancer and the CNS--view from the chair. 2008 Int J Obes (Lond) pmid:18719594
Lopaschuk GD AMP-activated protein kinase control of energy metabolism in the ischemic heart. 2008 Int J Obes (Lond) pmid:18719595
Lane MD et al. Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. 2008 Int J Obes (Lond) pmid:18719599
Ghadiminejad I and Saggerson ED A study of properties and abundance of the components of liver carnitine palmitoyltransferases in mitochondrial inner and outer membranes. Effects of hypothyroidism, fasting and a ketotic diabetic state. 1991 Biochem. J. pmid:1872797
Zammit VA and Arduini A The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. 2008 Cell Metab. pmid:18762014
Dzamko N et al. AMPK-independent pathways regulate skeletal muscle fatty acid oxidation. 2008 J. Physiol. (Lond.) pmid:18845612
Cha SH et al. Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18971329
Relat J et al. A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme. 2009 FEBS J. pmid:19049515
Ghadiminejad I and Saggerson D A proportion of rat liver mitochondrial carnitine palmitoyltransferase can be made activatable by malonyl-CoA. 1991 Biochim. Biophys. Acta pmid:1911872
Coletta DK et al. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. 2009 Diabetologia pmid:19169664
Lavarías S et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). 2009 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:19171199
Wang Q et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. 2009 Hepatology pmid:19177596
Frøsig C et al. Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19190265
Ussher JR and Lopaschuk GD Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. 2009 Basic Res. Cardiol. pmid:19242641
Zhao Z et al. Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle. 2009 Life Sci. pmid:19250943
Katsuyama Y et al. Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. 2009 J. Biol. Chem. pmid:19258320
Lane MD and Cha SH Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. 2009 Biochem. Biophys. Res. Commun. pmid:19265677