Malonyl-coa

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Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Starvation D013217 47 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Placental Insufficiency D010927 6 associated lipids
Ketosis D007662 13 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypothyroidism D007037 32 associated lipids
Per page 10 20 | Total 20

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Authors Title Published Journal PubMed Link
Lane MD and Cha SH Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. 2009 Biochem. Biophys. Res. Commun. pmid:19265677
Rutkoski A and Jaworski JG Fatty acid synthetase from chloroplasts of soybean cotyledons: ACP activation and CoA inhibition. 1978 Biochem. Biophys. Res. Commun. pmid:718691
Takeshita M et al. Decrease of palmitoyl-CoA elongation in platelets and leukocytes in the patient of hereditary methemoglobinemia associated with mental retardation. 1987 Biochem. Biophys. Res. Commun. pmid:3675585
White JS Significance of differential effects of glucose and fructose on brain food signaling is uncertain. 2009 Biochem. Biophys. Res. Commun. pmid:19785993
Kashfi K et al. Effects of cholesterol loading of mouse macrophages on carnitine palmitoyltransferase activity and sensitivity to inhibition by malonyl-CoA. 1991 Biochem. Biophys. Res. Commun. pmid:2059202
Thupari JN et al. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. 2001 Biochem. Biophys. Res. Commun. pmid:11444828
Eaton S et al. Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. 2001 Biochem. Biophys. Res. Commun. pmid:11444876
Kashfi K and Cook GA Malonyl-CoA inhibits proteolysis of carnitine palmitoyltransferase. 1991 Biochem. Biophys. Res. Commun. pmid:1859420
Oguro S et al. Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. 2004 Biochem. Biophys. Res. Commun. pmid:15530429
Nicot C et al. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. 2004 Biochem. Biophys. Res. Commun. pmid:15541339
Dai J et al. Leucine-764 near the extreme C-terminal end of carnitine palmitoyltransferase I is important for activity. 2003 Biochem. Biophys. Res. Commun. pmid:12565845
Yoshida S et al. Stereospecific incorporation of hydrogens from NADPH in elongation of very long fatty acyl-CoA by swine cerebral microsomes. 1984 Biochem. Biophys. Res. Commun. pmid:6497886
Srinivasan KR and Kumar S Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis. 1981 Biochem. Biophys. Res. Commun. pmid:7247949
Guzmán M and Geelen MJ Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol. 1988 Biochem. Biophys. Res. Commun. pmid:3401227
Knudsen J and Grunnet I Primer specificity of mammalian mammary gland fatty acid synthetases. 1980 Biochem. Biophys. Res. Commun. pmid:7417345
Cook GA et al. Feeding of lovastatin to rats increases the activity of the hepatic mitochondrial outer carnitine palmitoyltransferase. 1988 Biochem. Biophys. Res. Commun. pmid:3342059
Guzmán M et al. Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA. 1987 Biochem. Biophys. Res. Commun. pmid:3426584
Suh DY et al. Evidence for catalytic cysteine-histidine dyad in chalcone synthase. 2000 Biochem. Biophys. Res. Commun. pmid:10973790
Abo-Hashema KA et al. Liver mitochondria, confirmed as intact by complete suppression of succinate uptake and oxidation, possess a carnitine palmitoyltransferase I that is totally inhibited by malonyl CoA. 1999 Biochem. Biophys. Res. Commun. pmid:10329463
Tokutake Y et al. Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. 2012 Biochem. Biophys. Res. Commun. pmid:22713453
Iio W et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. 2012 Biochem. Biophys. Res. Commun. pmid:22503976
Peñas M and Benito M Regulation of carnitine palmitoyltransferase activity in the liver and brown adipose tissue in the newborn rat: effect of starvation and hypothermia. 1986 Biochem. Biophys. Res. Commun. pmid:3964261
Nagi MN et al. Evidence for two separate beta-ketoacyl CoA reductase components of the hepatic microsomal fatty acid chain elongation system in the rat. 1989 Biochem. Biophys. Res. Commun. pmid:2692567
Saha AK et al. Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. 2004 Biochem. Biophys. Res. Commun. pmid:14733947
Tokutake Y et al. Coenzyme A and its thioester pools in fasted and fed rat tissues. 2010 Biochem. Biophys. Res. Commun. pmid:20933504
Brown NF et al. Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. 1997 Biochem. J. pmid:9355756
Roughan PG Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. 1997 Biochem. J. pmid:9355762
Grantham BD and Zammit VA Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats. 1986 Biochem. J. pmid:3814087
Moir AM and Zammit VA Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume. 1995 Biochem. J. pmid:7848296
Saggerson ED and Carpenter CA The effect of malonyl-CoA on overt and latent carnitine acyltransferase activities in rat liver and adipocyte mitochondria. 1983 Biochem. J. pmid:6860313
Jackson VN et al. Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster. 1999 Biochem. J. pmid:10417309
Kozaki A and Sasaki Y Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. 1999 Biochem. J. pmid:10215591
Alam N and Saggerson ED Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. 1998 Biochem. J. pmid:9693125
Saggerson ED Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA. 1982 Biochem. J. pmid:7092822
Zammit VA Regulation of hepatic fatty acid metabolism. The activities of mitochondrial and microsomal acyl-CoA:sn-glycerol 3-phosphate O-acyltransferase and the concentrations of malonyl-CoA, non-esterified and esterified carnitine, glycerol 3-phosphate, ketone bodies and long-chain acyl-CoA esters in livers of fed or starved pregnant, lactating and weaned rats. 1981 Biochem. J. pmid:7326003
Zammit VA The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. 1999 Biochem. J. pmid:10527927
Saggerson ED et al. Effects of thyroidectomy and starvation on the activity and properties of hepatic carnitine palmitoyltransferase. 1982 Biochem. J. pmid:7165724
Geelen MJ Medium-chain fatty acids as short-term regulators of hepatic lipogenesis. 1994 Biochem. J. pmid:7915110
Niot I et al. Involvement of microsomal vesicles in part of the sensitivity of carnitine palmitoyltransferase I to malonyl-CoA inhibition in mitochondrial fractions of rat liver. 1994 Biochem. J. pmid:7998995
Grantham BD and Zammit VA Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA. 1986 Biochem. J. pmid:3954755
Roughan G A semi-preparative enzymic synthesis of malonyl-CoA from [14C]acetate and 14CO2: labelling in the 1, 2 or 3 position. 1994 Biochem. J. pmid:8002939
Guzman M et al. Evidence against direct involvement of phosphorylation in the activation of carnitine palmitoyltransferase by okadaic acid in rat hepatocytes. 1994 Biochem. J. pmid:8010950
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Scholem RD and Brown GK Metabolism of malonic semialdehyde in man. 1983 Biochem. J. pmid:6418146
Awan MM and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation. 1993 Biochem. J. pmid:8216240
Mynatt RL et al. Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids. 1994 Biochem. J. pmid:8192665
Bird MI and Saggerson ED Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity. 1984 Biochem. J. pmid:6487267
Brass EP et al. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. 1990 Biochem. J. pmid:2327967
Kolodziej MP and Zammit VA Sensitivity of inhibition of rat liver mitochondrial outer-membrane carnitine palmitoyltransferase by malonyl-CoA to chemical- and temperature-induced changes in membrane fluidity. 1990 Biochem. J. pmid:2268270
Marsh EN et al. Subunit interactions in Propionibacterium shermanii methylmalonyl-CoA mutase studied by analytical ultracentrifugation. 1989 Biochem. J. pmid:2569862
Smith BK et al. Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. 2012 Biochem. J. pmid:22928974
Zammit VA et al. Target size analysis by radiation inactivation of carnitine palmitoyltransferase activity and malonyl-CoA binding in outer membranes from rat liver mitochondria. 1989 Biochem. J. pmid:2604707
Derrick JP and Ramsay RR L-carnitine acyltransferase in intact peroxisomes is inhibited by malonyl-CoA. 1989 Biochem. J. pmid:2590167
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Baquet A et al. Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes. 1991 Biochem. J. pmid:1989589
Ramsay RR et al. Carnitine palmitoyltransferase in human erythrocyte membrane. Properties and malonyl-CoA sensitivity. 1991 Biochem. J. pmid:2039446
Mikkelsen J et al. Stoichiometry of substrate binding to rat liver fatty acid synthetase. 1985 Biochem. J. pmid:4052054
Ghadiminejad I and Saggerson ED The relationship of rat liver overt carnitine palmitoyltransferase to the mitochondrial malonyl-CoA binding entity and to the latent palmitoyltransferase. 1990 Biochem. J. pmid:2241911
Mills SE et al. Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I. 1984 Biochem. J. pmid:6743235
Faye A et al. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity. 2005 Biochem. J. pmid:15498023
Walker TA et al. Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris. 1981 Biochem. J. pmid:6803763
Zammit VA Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA. 1984 Biochem. J. pmid:6712621
Cook GA et al. Altered sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA in ketotic diabetic rats. 1984 Biochem. J. pmid:6426472
Cook GA and Cox KA Hysteretic behaviour of carnitine palmitoyltransferase. The effect of preincubation with malonyl-CoA. 1986 Biochem. J. pmid:3790097
Lloyd AC et al. Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. 1986 Biochem. J. pmid:3800884
Saggerson ED and Carpenter CA Sensitivity of brown-adipose-tissue carnitine palmitoyltransferase to inhibition by malonyl-CoA. 1982 Biochem. J. pmid:7115330
Weinstein I et al. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. 1986 Biochem. J. pmid:3800903
Robinson IN and Zammit VA Sensitivity of carnitine acyltransferase I to malonly-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo. 1982 Biochem. J. pmid:7126192
Saggerson ED Does fasting decrease the inhibitory effect of malonyl-CoA on hepatic beta-oxidation? 1982 Biochem. J. pmid:7159415
Saggerson ED and Carpenter CA Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy. 1982 Biochem. J. pmid:7165725
Schofield PS et al. Altered interactions between lipogenesis and fatty acid oxidation in regenerating rat liver. 1987 Biochem. J. pmid:3593202
McGarry JD and Foster DW Importance of experimental conditions in evaluating the malonyl-CoA sensitivity of liver carnitine acyltransferase. Studies with fed and starved rats. 1981 Biochem. J. pmid:7340831
McGarry JD and Brown NF Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity. 2000 Biochem. J. pmid:10861226
Walker KA et al. Fluazifop, a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. 1988 Biochem. J. pmid:2902848
Roughan PG et al. On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts. 1979 Biochem. J. pmid:534525
Park EA et al. Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I. 1995 Biochem. J. pmid:7575418
Kolodziej MP and Zammit VA Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes. 1990 Biochem. J. pmid:2327991
Broadway NM and Saggerson ED Solubilization and separation of two distinct carnitine acyltransferases from hepatic microsomes: characterization of the malonyl-CoA-sensitive enzyme. 1995 Biochem. J. pmid:7575437
Grantham BD and Zammit VA Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes. 1988 Biochem. J. pmid:3277623
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Brady LJ et al. Hepatic mitochondrial inner-membrane properties, beta-oxidation and carnitine palmitoyltransferases A and B. Effects of genetic obesity and starvation. 1986 Biochem. J. pmid:3954744
Saggerson ED et al. Cycloheximide blocks changes in rat liver carnitine palmitoyltransferase 1 activity in starvation. 1984 Biochem. J. pmid:6508756
Zammit VA et al. Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0 degree C and 37 degrees C with a fixed concentration of malonyl-CoA. 1984 Biochem. J. pmid:6477517
Cook GA Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. 1984 Biochem. J. pmid:6525169
Brindle NP et al. Regulation of carnitine palmitoyltransferase activity by malonyl-CoA in mitochondria from sheep liver, a tissue with a low capacity for fatty acid synthesis. 1985 Biochem. J. pmid:4084227
Bird MI et al. Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. 1985 Biochem. J. pmid:3977877
Murthy MS and Pande SV Characterization of a solubilized malonyl-CoA-sensitive carnitine palmitoyltransferase from the mitochondrial outer membrane as a protein distinct from the malonyl-CoA-insensitive carnitine palmitoyltransferase of the inner membrane. 1990 Biochem. J. pmid:2363698
McCormick K et al. Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation. 1983 Biochem. J. pmid:6661211
Lee GY et al. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. 2004 Biochem. J. pmid:14641110
Zammit VA Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro. 1983 Biochem. J. pmid:6870813
Zammit VA and Corstorphine CG Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. 1985 Biochem. J. pmid:4062901
Sanchez J and Harwood JL Products of fatty acid synthesis by a particulate fraction from germinating pea (Pisum sativum L.). 1981 Biochem. J. pmid:7337704
Brady LJ et al. Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. 1985 Biochem. J. pmid:4091801
Fraser F et al. Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane. 1997 Biochem. J. pmid:9169604
Pégorier JP et al. Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols. 1988 Biochem. J. pmid:3355499
Skelly RH et al. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. 1998 Biochem. J. pmid:9531497
Knudsen J Medium-chain fatty acid synthesis in lactating-rabbit mammary gland. Intracellular concentration and specificity of medium-chain acyl thioester hydrolase. 1979 Biochem. J. pmid:574008
Broadway NM and Saggerson ED Effect of membrane environment on the activity and inhibitability by malonyl-CoA of the carnitine acyltransferase of hepatic microsomal membranes. 1997 Biochem. J. pmid:9065760
Child CJ and Shoolingin-Jordan PM Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. 1998 Biochem. J. pmid:9480912
Brady PS and Brady LJ Action in vivo and in vitro of 2-tetradecylglycidic acid, 2-tetradecylglycidyl-CoA and 2-tetradecylglycidylcarnitine on hepatic carnitine palmitoyltransferase. 1986 Biochem. J. pmid:3800962