Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Starvation D013217 47 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Placental Insufficiency D010927 6 associated lipids
Ketosis D007662 13 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypothyroidism D007037 32 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Brown NF et al. Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. 1997 Biochem. J. pmid:9355756
Roughan PG Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. 1997 Biochem. J. pmid:9355762
Jackson VN et al. Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster. 1999 Biochem. J. pmid:10417309
Murthy MS and Pande SV Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes. 1987 Biochem. J. pmid:3435481
Kozaki A and Sasaki Y Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. 1999 Biochem. J. pmid:10215591
Saggerson ED Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA. 1982 Biochem. J. pmid:7092822
Zammit VA Regulation of hepatic fatty acid metabolism. The activities of mitochondrial and microsomal acyl-CoA:sn-glycerol 3-phosphate O-acyltransferase and the concentrations of malonyl-CoA, non-esterified and esterified carnitine, glycerol 3-phosphate, ketone bodies and long-chain acyl-CoA esters in livers of fed or starved pregnant, lactating and weaned rats. 1981 Biochem. J. pmid:7326003
Kasumov T et al. Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. 2005 Biochem. J. pmid:15773815
Geelen MJ Medium-chain fatty acids as short-term regulators of hepatic lipogenesis. 1994 Biochem. J. pmid:7915110
Moir AM and Zammit VA Rapid switch of hepatic fatty acid metabolism from oxidation to esterification during diurnal feeding of meal-fed rats correlates with changes in the properties of acetyl-CoA carboxylase, but not of carnitine palmitoyltransferase I. 1993 Biochem. J. pmid:8097087
Grantham BD and Zammit VA Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA. 1986 Biochem. J. pmid:3954755
Guzman M et al. Evidence against direct involvement of phosphorylation in the activation of carnitine palmitoyltransferase by okadaic acid in rat hepatocytes. 1994 Biochem. J. pmid:8010950
Scholem RD and Brown GK Metabolism of malonic semialdehyde in man. 1983 Biochem. J. pmid:6418146
Awan MM and Saggerson ED Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation. 1993 Biochem. J. pmid:8216240
Bird MI and Saggerson ED Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase. 1985 Biochem. J. pmid:4052033
Mynatt RL et al. Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids. 1994 Biochem. J. pmid:8192665
Edwards MR et al. Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites. 1985 Biochem. J. pmid:4052034
Bird MI and Saggerson ED Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity. 1984 Biochem. J. pmid:6487267
Marsh EN et al. Subunit interactions in Propionibacterium shermanii methylmalonyl-CoA mutase studied by analytical ultracentrifugation. 1989 Biochem. J. pmid:2569862
Zammit VA et al. Target size analysis by radiation inactivation of carnitine palmitoyltransferase activity and malonyl-CoA binding in outer membranes from rat liver mitochondria. 1989 Biochem. J. pmid:2604707
Derrick JP and Ramsay RR L-carnitine acyltransferase in intact peroxisomes is inhibited by malonyl-CoA. 1989 Biochem. J. pmid:2590167
Civelek VN et al. Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP. 1996 Biochem. J. pmid:8809055
Mikkelsen J et al. Stoichiometry of substrate binding to rat liver fatty acid synthetase. 1985 Biochem. J. pmid:4052054
Moir AM and Zammit VA Monitoring of changes in hepatic fatty acid and glycerolipid metabolism during the starved-to-fed transition in vivo. Studies on awake, unrestrained rats. 1993 Biochem. J. pmid:8424771
Mills SE et al. Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I. 1984 Biochem. J. pmid:6743235
Faye A et al. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity. 2005 Biochem. J. pmid:15498023
Walker TA et al. Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris. 1981 Biochem. J. pmid:6803763
Zammit VA Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA. 1984 Biochem. J. pmid:6712621
Rendina AR and Cheng D Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. 2005 Biochem. J. pmid:15715522
Cook GA et al. Altered sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA in ketotic diabetic rats. 1984 Biochem. J. pmid:6426472
Leadlay PF and Fuller JQ Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. Studies with specifically tritiated (2R)-methylmalonyl-CoA as substrate. 1983 Biochem. J. pmid:6311169
Fuller JQ and Leadlay PF Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water. 1983 Biochem. J. pmid:6311170
Jones AV et al. Inhibition of plant fatty acid synthesis by nitroimidazoles. 1981 Biochem. J. pmid:7325993
McGarry JD and Foster DW Importance of experimental conditions in evaluating the malonyl-CoA sensitivity of liver carnitine acyltransferase. Studies with fed and starved rats. 1981 Biochem. J. pmid:7340831
Walker KA et al. Fluazifop, a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. 1988 Biochem. J. pmid:2902848
Grantham BD and Zammit VA Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes. 1988 Biochem. J. pmid:3277623
Brady LJ et al. Hepatic mitochondrial inner-membrane properties, beta-oxidation and carnitine palmitoyltransferases A and B. Effects of genetic obesity and starvation. 1986 Biochem. J. pmid:3954744
Zammit VA et al. Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0 degree C and 37 degrees C with a fixed concentration of malonyl-CoA. 1984 Biochem. J. pmid:6477517
Brindle NP et al. Regulation of carnitine palmitoyltransferase activity by malonyl-CoA in mitochondria from sheep liver, a tissue with a low capacity for fatty acid synthesis. 1985 Biochem. J. pmid:4084227
Zammit VA Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization. 1983 Biochem. J. pmid:6626153
McCormick K et al. Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation. 1983 Biochem. J. pmid:6661211
Lee GY et al. Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. 2004 Biochem. J. pmid:14641110
Zammit VA and Corstorphine CG Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states. 1985 Biochem. J. pmid:4052052
Zammit VA and Corstorphine CG Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. 1985 Biochem. J. pmid:4062901
Sanchez J and Harwood JL Products of fatty acid synthesis by a particulate fraction from germinating pea (Pisum sativum L.). 1981 Biochem. J. pmid:7337704
Brady LJ et al. Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. 1985 Biochem. J. pmid:4091801
Drynan L et al. The role of changes in the sensitivity of hepatic mitochondrial overt carnitine palmitoyltransferase in determining the onset of the ketosis of starvation in the rat. 1996 Biochem. J. pmid:8836117
Fraser F et al. Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane. 1997 Biochem. J. pmid:9169604
Pégorier JP et al. Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols. 1988 Biochem. J. pmid:3355499
Broadway NM and Saggerson ED Effect of membrane environment on the activity and inhibitability by malonyl-CoA of the carnitine acyltransferase of hepatic microsomal membranes. 1997 Biochem. J. pmid:9065760