Malonyl-coa

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Malonyl-coa

Download all related citations
Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Wu J et al. Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli. 2017 J. Ind. Microbiol. Biotechnol. pmid:28324236
Yilmaz JL et al. Determination of Substrate Preferences for Desaturases and Elongases for Production of Docosahexaenoic Acid from Oleic Acid in Engineered Canola. 2017 Lipids pmid:28197856
Lehmann D et al. Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features. 2017 Int J Mol Sci pmid:28054946
Liang JL et al. A novel process for obtaining pinosylvin using combinatorial bioengineering in Escherichia coli. 2016 World J. Microbiol. Biotechnol. pmid:27116968
Wu J et al. Efficient biosynthesis of (2S)-pinocembrin from d-glucose by integrating engineering central metabolic pathways with a pH-shift control strategy. 2016 Bioresour. Technol. pmid:27450982
Cao W et al. Improved pinocembrin production in Escherichia coli by engineering fatty acid synthesis. 2016 J. Ind. Microbiol. Biotechnol. pmid:26733394
Vavrova E et al. Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:27507552
Gray JP et al. Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26786775
Martin J et al. Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein. 2016 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26767982
Meng L et al. Enhanced production of avermectin by deletion of type III polyketide synthases biosynthetic cluster rpp in Streptomyces avermitilis. 2016 Lett. Appl. Microbiol. pmid:27538855
Mo S et al. Improvement of FK506 Production in the High-Yielding Strain Streptomyces sp. RM7011 by Engineering the Supply of Allylmalonyl-CoA Through a Combination of Genetic and Chemical Approach. 2016 J. Microbiol. Biotechnol. pmid:26502733
Go Y et al. Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis. 2016 Diabetes pmid:27385159
Avidan O et al. Enhanced acetyl-CoA production is associated with increased triglyceride accumulation in the green alga Chlorella desiccata. 2015 J. Exp. Bot. pmid:25922486
Gao BW et al. Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis. 2015 Bioorg. Med. Chem. Lett. pmid:25677661
ElAzzouny MA et al. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. 2015 PLoS ONE pmid:26107620
Wang YY et al. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. 2015 Protein Pept. Lett. pmid:25267255
Levitan O et al. An RNA interference knock-down of nitrate reductase enhances lipid biosynthesis in the diatom Phaeodactylum tricornutum. 2015 Plant J. pmid:26473332
Miyazawa T et al. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit. 2015 J. Biol. Chem. pmid:26378232
Li M et al. De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae. 2015 Metab. Eng. pmid:26344106
Wu J et al. Enhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli. 2015 Sci Rep pmid:26323217
Loubière C et al. Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells. 2015 Oncotarget pmid:26002551
Martínez de Morentin PB et al. Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. 2015 Endocrinology pmid:25535827
Jin Z et al. Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE. 2015 J. Biol. Chem. pmid:26070565
Colak G et al. Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. 2015 Mol. Cell Proteomics pmid:26320211
Kerner J et al. Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation. 2014 J. Biol. Chem. pmid:24558043
Griffith DA et al. Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes. 2014 J. Med. Chem. pmid:25423286
Wu J et al. Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2S)-Naringenin Production from l-Tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:25239896
Mandrup S et al. In memoriam: M. Daniel Lane, 1930-2014. 2014 Trends Endocrinol. Metab. pmid:25084731
Zordoky BN et al. AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation. 2014 Circ. Res. pmid:25001074
Shi S et al. Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1. 2014 MBio pmid:24803522
Zhu S et al. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:24610848
Koirala N et al. Glycosylation and subsequent malonylation of isoflavonoids in E. coli: strain development, production and insights into future metabolic perspectives. 2014 J. Ind. Microbiol. Biotechnol. pmid:25189810
Dunn BJ et al. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. 2014 Biochemistry pmid:24871074
Xu P et al. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25049420
Xu P et al. Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. 2014 ACS Chem. Biol. pmid:24191643
Xu Y et al. Lipid accumulation is ahead of epithelial-to-mesenchymal transition and therapeutic intervention by acetyl-CoA carboxylase 2 silence in diabetic nephropathy. 2014 Metab. Clin. Exp. pmid:24650564
Bhatia H et al. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. 2014 Biochim. Biophys. Acta pmid:24560669
Karunakaran R et al. Malonate catabolism does not drive N2 fixation in legume nodules. 2013 Appl. Environ. Microbiol. pmid:23666330
Celato A et al. A new case of malonic aciduria with a presymptomatic diagnosis and an early treatment. 2013 Brain Dev. pmid:23177061
Cacho RA et al. Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. 2013 ACS Chem. Biol. pmid:23978092
Cheng R et al. Cloning and functional analysis of putative malonyl-CoA:acyl-carrier protein transacylase gene from the docosahexaenoic acid-producer Schizochytrium sp. TIO1101. 2013 World J. Microbiol. Biotechnol. pmid:23292648
Lewandowski ED et al. Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. 2013 Circ. Res. pmid:22982985
Mercier R et al. Excess membrane synthesis drives a primitive mode of cell proliferation. 2013 Cell pmid:23452849
Kage H et al. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. 2013 Chem. Biol. pmid:23790487
Vandhana S et al. Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. 2013 Biochim. Biophys. Acta pmid:23816424
Musiol EM et al. The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. 2013 Chembiochem pmid:23828654
Awakawa T et al. 4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. 2013 Chembiochem pmid:23609937
Gokulan K et al. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. 2013 J. Biol. Chem. pmid:23615910
Miura S et al. Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23695215
Koyuncu E et al. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. 2013 PLoS Pathog. pmid:23696731
Gao S et al. Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. 2013 Physiol. Behav. pmid:23680429
Albanesi D et al. Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. 2013 PLoS Pathog. pmid:23300457
Zhabyeyev P et al. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. 2013 Cardiovasc. Res. pmid:23257023
Knobloch M et al. Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. 2013 Nature pmid:23201681
Fritz V et al. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. 2013 Oncogene pmid:23208508
Derdak Z et al. Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. 2013 J. Hepatol. pmid:23211317
Tang X et al. Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae. 2013 Metab. Eng. pmid:23353549
Rao G et al. Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. 2013 Appl. Microbiol. Biotechnol. pmid:23358999
Kimber NE et al. Skeletal muscle fat metabolism after exercise in humans: influence of fat availability. 2013 J. Appl. Physiol. pmid:23519231
Gao S et al. Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23736540
Liu C et al. Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. 2013 PLoS ONE pmid:24073271
Zhang M et al. The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation. 2013 Mol. Cell. Biol. pmid:24081331
Gao S et al. Hypothalamic malonyl-CoA and the control of food intake. 2013 Physiol. Behav. pmid:23988346
Bertoni G A key step in phlorotannin biosynthesis revealed. 2013 Plant Cell pmid:23995082
Valsangkar D and Downs SM A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. 2013 Biol. Reprod. pmid:23863407
Zabala D et al. Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus. 2013 Metab. Eng. pmid:24148183
Zhang X et al. Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase. 2012 Jan-Feb Biotechnol. Prog. pmid:22038854
Albaugh VL et al. Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents. 2012 Schizophr Bull pmid:20494946
Natarajan S et al. Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP. 2012 Mol. Cells pmid:22134719
Smith AC and Cronan JE Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo. 2012 J. Bacteriol. pmid:22037404
Monsénégo J et al. Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. 2012 J. Hepatol. pmid:22037024
Rathnasingh C et al. Production of 3-hydroxypropionic acid via malonyl-CoA pathway using recombinant Escherichia coli strains. 2012 J. Biotechnol. pmid:21723339
Prada CE et al. Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy. 2012 Pediatrics pmid:22778304
Smith BK et al. Identification of a novel malonyl-CoA IC(50) for CPT-I: implications for predicting in vivo fatty acid oxidation rates. 2012 Biochem. J. pmid:22928974
Xue J et al. Novel compound heterozygous mutation of MLYCD in a Chinese patient with malonic aciduria. 2012 Mol. Genet. Metab. pmid:22104738
Reindl BA et al. Sani-cloth wipe mimics rare enzyme deficiency malonic aciduria on newborn screen. 2012 Pediatrics pmid:23071203
Glund S et al. Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice. 2012 Diabetologia pmid:22532389
Guo H et al. Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. 2012 Lipids Health Dis pmid:22243683
Cherbuy C et al. Oleate metabolism in pig enterocytes is characterized by an increased oxidation rate in the presence of a high esterification rate within two days after birth. 2012 J. Nutr. pmid:22223579
Tokutake Y et al. Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. 2012 Biochem. Biophys. Res. Commun. pmid:22713453
Jung SY et al. Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells. 2012 J. Cell. Biochem. pmid:22786746
Kolwicz SC et al. Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. 2012 Circ. Res. pmid:22730442
Iio W et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. 2012 Biochem. Biophys. Res. Commun. pmid:22503976
Jensen K et al. Polyketide proofreading by an acyltransferase-like enzyme. 2012 Chem. Biol. pmid:22444588
Ussher JR et al. Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. 2012 Cardiovasc. Res. pmid:22436846
Foster DW Malonyl-CoA: the regulator of fatty acid synthesis and oxidation. 2012 J. Clin. Invest. pmid:22833869
Ellis JM and Wolfgang MJ A genetically encoded metabolite sensor for malonyl-CoA. 2012 Chem. Biol. pmid:23102226
Jeya M et al. A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency. 2012 Mol Biosyst pmid:23059854
Moore RG et al. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. 2012 PLoS ONE pmid:22509304
Morash AJ and McClelland GB Regulation of carnitine palmitoyltransferase (CPT) I during fasting in rainbow trout (Oncorhynchus mykiss) promotes increased mitochondrial fatty acid oxidation. 2011 Nov-Dec Physiol. Biochem. Zool. pmid:22030855
Chen Q et al. Fatty acid synthase inhibitors separated from oiltea camellia by high-speed counter-current chromatography. 2011 Jun-Jul J. Food Sci. pmid:22417422
Gilibili RR et al. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues. 2011 Biomed. Chromatogr. pmid:21381064
Gao S et al. Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21508288
Lauzier B et al. Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart. 2011 J. Mol. Cell. Cardiol. pmid:21510957
Meng X et al. Increasing fatty acid production in E. coli by simulating the lipid accumulation of oleaginous microorganisms. 2011 J. Ind. Microbiol. Biotechnol. pmid:20972897
Keung W et al. Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet. 2011 J. Cardiovasc. Pharmacol. pmid:20980918
Mo S et al. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. 2011 J. Am. Chem. Soc. pmid:21175203
Wolfgang MJ and Lane MD Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity. 2011 FEBS J. pmid:21199367
Reamy AA and Wolfgang MJ Carnitine palmitoyltransferase-1c gain-of-function in the brain results in postnatal microencephaly. 2011 J. Neurochem. pmid:21592121
Gao S et al. Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21593415