Malonyl-coa

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

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All references with Malonyl-coa

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Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Wu J et al. Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli. 2017 J. Ind. Microbiol. Biotechnol. pmid:28324236
Yilmaz JL et al. Determination of Substrate Preferences for Desaturases and Elongases for Production of Docosahexaenoic Acid from Oleic Acid in Engineered Canola. 2017 Lipids pmid:28197856
Lehmann D et al. Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features. 2017 Int J Mol Sci pmid:28054946
Liang JL et al. A novel process for obtaining pinosylvin using combinatorial bioengineering in Escherichia coli. 2016 World J. Microbiol. Biotechnol. pmid:27116968
Wu J et al. Efficient biosynthesis of (2S)-pinocembrin from d-glucose by integrating engineering central metabolic pathways with a pH-shift control strategy. 2016 Bioresour. Technol. pmid:27450982
Cao W et al. Improved pinocembrin production in Escherichia coli by engineering fatty acid synthesis. 2016 J. Ind. Microbiol. Biotechnol. pmid:26733394
Vavrova E et al. Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:27507552
Gray JP et al. Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26786775
Martin J et al. Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein. 2016 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26767982
Meng L et al. Enhanced production of avermectin by deletion of type III polyketide synthases biosynthetic cluster rpp in Streptomyces avermitilis. 2016 Lett. Appl. Microbiol. pmid:27538855
Mo S et al. Improvement of FK506 Production in the High-Yielding Strain Streptomyces sp. RM7011 by Engineering the Supply of Allylmalonyl-CoA Through a Combination of Genetic and Chemical Approach. 2016 J. Microbiol. Biotechnol. pmid:26502733
Go Y et al. Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis. 2016 Diabetes pmid:27385159
Avidan O et al. Enhanced acetyl-CoA production is associated with increased triglyceride accumulation in the green alga Chlorella desiccata. 2015 J. Exp. Bot. pmid:25922486
Gao BW et al. Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis. 2015 Bioorg. Med. Chem. Lett. pmid:25677661
ElAzzouny MA et al. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. 2015 PLoS ONE pmid:26107620
Wang YY et al. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. 2015 Protein Pept. Lett. pmid:25267255
Levitan O et al. An RNA interference knock-down of nitrate reductase enhances lipid biosynthesis in the diatom Phaeodactylum tricornutum. 2015 Plant J. pmid:26473332
Miyazawa T et al. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit. 2015 J. Biol. Chem. pmid:26378232
Li M et al. De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae. 2015 Metab. Eng. pmid:26344106
Wu J et al. Enhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli. 2015 Sci Rep pmid:26323217
Loubière C et al. Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells. 2015 Oncotarget pmid:26002551
Martínez de Morentin PB et al. Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. 2015 Endocrinology pmid:25535827
Jin Z et al. Compartmentation of Metabolism of the C12-, C9-, and C5-n-dicarboxylates in Rat Liver, Investigated by Mass Isotopomer Analysis: ANAPLEROSIS FROM DODECANEDIOATE. 2015 J. Biol. Chem. pmid:26070565
Colak G et al. Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. 2015 Mol. Cell Proteomics pmid:26320211
Kerner J et al. Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation. 2014 J. Biol. Chem. pmid:24558043
Griffith DA et al. Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes. 2014 J. Med. Chem. pmid:25423286
Wu J et al. Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2S)-Naringenin Production from l-Tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:25239896
Mandrup S et al. In memoriam: M. Daniel Lane, 1930-2014. 2014 Trends Endocrinol. Metab. pmid:25084731
Zordoky BN et al. AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation. 2014 Circ. Res. pmid:25001074
Shi S et al. Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1. 2014 MBio pmid:24803522
Zhu S et al. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:24610848
Koirala N et al. Glycosylation and subsequent malonylation of isoflavonoids in E. coli: strain development, production and insights into future metabolic perspectives. 2014 J. Ind. Microbiol. Biotechnol. pmid:25189810
Dunn BJ et al. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. 2014 Biochemistry pmid:24871074
Xu P et al. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25049420
Xu P et al. Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. 2014 ACS Chem. Biol. pmid:24191643
Xu Y et al. Lipid accumulation is ahead of epithelial-to-mesenchymal transition and therapeutic intervention by acetyl-CoA carboxylase 2 silence in diabetic nephropathy. 2014 Metab. Clin. Exp. pmid:24650564
Bhatia H et al. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. 2014 Biochim. Biophys. Acta pmid:24560669
Karunakaran R et al. Malonate catabolism does not drive N2 fixation in legume nodules. 2013 Appl. Environ. Microbiol. pmid:23666330
Cacho RA et al. Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. 2013 ACS Chem. Biol. pmid:23978092
Kage H et al. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. 2013 Chem. Biol. pmid:23790487
Gokulan K et al. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. 2013 J. Biol. Chem. pmid:23615910
Miura S et al. Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23695215
Koyuncu E et al. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. 2013 PLoS Pathog. pmid:23696731
Gao S et al. Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23736540
Liu C et al. Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. 2013 PLoS ONE pmid:24073271
Zhang M et al. The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation. 2013 Mol. Cell. Biol. pmid:24081331
Gao S et al. Hypothalamic malonyl-CoA and the control of food intake. 2013 Physiol. Behav. pmid:23988346
Bertoni G A key step in phlorotannin biosynthesis revealed. 2013 Plant Cell pmid:23995082
Valsangkar D and Downs SM A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. 2013 Biol. Reprod. pmid:23863407
Zabala D et al. Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus. 2013 Metab. Eng. pmid:24148183