Malonyl-coa

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3249 references associated with Malonyl-coa in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for Malonyl-coa

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonyl-coa

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Weight Gain D015430 101 associated lipids
Hypoglycemia D007003 13 associated lipids
Per page 10 20 | Total 20

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Malonyl-coa

Download all related citations
Per page 10 20 50 100 | Total 927
Authors Title Published Journal PubMed Link
Meehan MJ et al. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. 2011 Biochemistry pmid:21069965
Kudej RK et al. Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. 2011 Cardiovasc. Res. pmid:21835931
Serviddio G et al. Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet. 2011 PLoS ONE pmid:21909411
Keung W et al. Chronic central leptin decreases food intake and improves glucose tolerance in diet-induced obese mice independent of hypothalamic malonyl CoA levels and skeletal muscle insulin sensitivity. 2011 Endocrinology pmid:21914780
Jenei ZA et al. Packing of transmembrane domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and malonyl-CoA sensitivity of the mitochondrial outer membrane protein. 2011 FASEB J. pmid:21917985
Sloan JL et al. Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria. 2011 Nat. Genet. pmid:21841779
Naganuma T et al. Biochemical characterization of the very long-chain fatty acid elongase ELOVL7. 2011 FEBS Lett. pmid:21959040
Hammerbacher A et al. Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection. 2011 Plant Physiol. pmid:21865488
Gilibili RR et al. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues. 2011 Biomed. Chromatogr. pmid:21381064
Lauzier B et al. Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart. 2011 J. Mol. Cell. Cardiol. pmid:21510957
Bengtsson C et al. Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. 2011 Bioorg. Med. Chem. pmid:21515056
Meng X et al. Increasing fatty acid production in E. coli by simulating the lipid accumulation of oleaginous microorganisms. 2011 J. Ind. Microbiol. Biotechnol. pmid:20972897
Keung W et al. Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet. 2011 J. Cardiovasc. Pharmacol. pmid:20980918
Geisler JG Targeting energy expenditure via fuel switching and beyond. 2011 Diabetologia pmid:20953861
Olson DP et al. Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20368432
Martinez MA et al. A novel role of malonyl-ACP in lipid homeostasis. 2010 Biochemistry pmid:20201588
Lopaschuk GD et al. Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite. 2010 Pharmacol. Rev. pmid:20392806
Lin X et al. Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid {beta}-oxidation in liver of neonatal swine. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20237302
Maharjan S et al. Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides. 2010 Biotechnol. Lett. pmid:19838628
Takagi M et al. Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus. 2010 J. Bacteriol. pmid:19854913
Sucajtys-Szulc E et al. Differential effect of prolonged food restriction and fasting on hypothalamic malonyl-CoA concentration and expression of orexigenic and anorexigenic neuropeptides genes in rats. 2010 Neuropeptides pmid:20004973
Sharma V et al. Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria. 2010 Mol. Cell. Biochem. pmid:19862603
Kharel MK et al. Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. 2010 Org. Lett. pmid:20486694
Morash AJ et al. Genome duplication events have led to a diversification in the CPT I gene family in fish. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20519364
Onorato JM et al. Liquid-liquid extraction coupled with LC/MS/MS for monitoring of malonyl-CoA in rat brain tissue. 2010 Anal Bioanal Chem pmid:20549491
Thyfault JP et al. Metabolic profiling of muscle contraction in lean compared with obese rodents. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20504904
Hamed RB et al. Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. 2010 Chem. Commun. (Camb.) pmid:20162132
Liu T et al. Quantitative analysis and engineering of fatty acid biosynthesis in E. coli. 2010 Metab. Eng. pmid:20184964
Guzmán-Ruiz R et al. Sensitivity of cardiac carnitine palmitoyltransferase to malonyl-CoA is regulated by leptin: similarities with a model of endogenous hyperleptinemia. 2010 Endocrinology pmid:20056820
Price NT et al. Alternative exon usage in the single CPT1 gene of Drosophila generates functional diversity in the kinetic properties of the enzyme: differential expression of alternatively spliced variants in Drosophila tissues. 2010 J. Biol. Chem. pmid:20061394
Morita H et al. A structure-based mechanism for benzalacetone synthase from Rheum palmatum. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20080733
Footitt EJ et al. Use of a long-chain triglyceride-restricted/medium-chain triglyceride-supplemented diet in a case of malonyl-CoA decarboxylase deficiency with cardiomyopathy. 2010 J. Inherit. Metab. Dis. pmid:20549361
Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Hozyasz KK et al. Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate. 2010 Int J Oral Sci pmid:21125791
Tokutake Y et al. Coenzyme A and its thioester pools in fasted and fed rat tissues. 2010 Biochem. Biophys. Res. Commun. pmid:20933504
Kim DH et al. Molecular characterization of flavonoid malonyltransferase from Oryza sativa. 2009 Nov-Dec Plant Physiol. Biochem. pmid:19733090
Zhao Z et al. Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle. 2009 Life Sci. pmid:19250943
Katsuyama Y et al. Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa. 2009 J. Biol. Chem. pmid:19258320
Lane MD and Cha SH Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. 2009 Biochem. Biophys. Res. Commun. pmid:19265677
Ide T et al. Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver. 2009 J. Nutr. Sci. Vitaminol. pmid:19352061
Celik A et al. Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia. 2009 Oncol. Rep. pmid:19288015
Relat J et al. A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme. 2009 FEBS J. pmid:19049515
Dean JT et al. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. 2009 Cell Metab. pmid:19490907
Downs SM et al. Fatty acid oxidation and meiotic resumption in mouse oocytes. 2009 Mol. Reprod. Dev. pmid:19455666
Tosin M et al. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. 2009 Chembiochem pmid:19507202
Cha SH and Lane MD Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway. 2009 Biochem. Biophys. Res. Commun. pmid:19523445
Metz JG et al. Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. 2009 Plant Physiol. Biochem. pmid:19272783
Nilsson LA et al. Prolactin suppresses malonyl-CoA concentration in human adipose tissue. 2009 Horm. Metab. Res. pmid:19551610
Miyanaga A and Horinouchi S Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases. 2009 J. Antibiot. pmid:19557027
Zha W et al. Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering. 2009 Metab. Eng. pmid:19558964
Awakawa T et al. Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. 2009 Chem. Biol. pmid:19549600
Eustáquio AS et al. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19590008
Kitazawa H et al. Development of a high-density assay for long-chain fatty acyl-CoA elongases. 2009 Lipids pmid:19575253
Fowler ZL et al. Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. 2009 Appl. Environ. Microbiol. pmid:19633125
Schink B An alternative to the glyoxylate shunt. 2009 Mol. Microbiol. pmid:19682245
Saez G et al. Gene expression and protein content in relation to intramuscular fat content in Muscovy and Pekin ducks. 2009 Poult. Sci. pmid:19834090
Ma SM et al. Complete reconstitution of a highly reducing iterative polyketide synthase. 2009 Science pmid:19900898
White JS Significance of differential effects of glucose and fructose on brain food signaling is uncertain. 2009 Biochem. Biophys. Res. Commun. pmid:19785993
Singh P et al. Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives. 2009 J Enzyme Inhib Med Chem pmid:18608763
Singh SP et al. Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE). 2009 Aging (Albany NY) pmid:20157589
Coletta DK et al. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. 2009 Diabetologia pmid:19169664
Ussher JR and Lopaschuk GD Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. 2009 Basic Res. Cardiol. pmid:19242641
Frøsig C et al. Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19190265
Lavarías S et al. Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). 2009 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:19171199
Wang Q et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. 2009 Hepatology pmid:19177596
Dzamko N et al. AMPK-independent pathways regulate skeletal muscle fatty acid oxidation. 2008 J. Physiol. (Lond.) pmid:18845612
Cha SH et al. Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18971329
Minkler PE et al. Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue. 2008 Anal. Biochem. pmid:18355435
Zhou L et al. Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18083904
Sharma V et al. Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18203848
Janovská A et al. AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. 2008 Mol. Cell. Endocrinol. pmid:18255222
Bortolami S et al. Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I. 2008 J. Bioenerg. Biomembr. pmid:18214656
Wolfgang MJ and Lane MD Hypothalamic malonyl-coenzyme A and the control of energy balance. 2008 Mol. Endocrinol. pmid:18356287
Hayashi O and Satoh K Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. 2008 Biosci. Biotechnol. Biochem. pmid:18323644
Schujman GE et al. A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism. 2008 Mol. Microbiol. pmid:18384517
Morash AJ et al. Intertissue regulation of carnitine palmitoyltransferase I (CPTI): mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss). 2008 Biochim. Biophys. Acta pmid:18359285
Funabashi M et al. Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus. 2008 J. Biol. Chem. pmid:18364359
Ussher JR and Lopaschuk GD The malonyl CoA axis as a potential target for treating ischaemic heart disease. 2008 Cardiovasc. Res. pmid:18499682
Kong R et al. Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis. 2008 J. Am. Chem. Soc. pmid:18529057
López M et al. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. 2008 Cell Metab. pmid:18460330
Saggerson D Malonyl-CoA, a key signaling molecule in mammalian cells. 2008 Annu. Rev. Nutr. pmid:18598135
Yatscoff MA et al. Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart. 2008 Pediatr. Res. pmid:18614968
Kerner J et al. Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation. 2008 Arch. Physiol. Biochem. pmid:18629681
Deshaies Y AMP kinase: heart, cancer and the CNS--view from the chair. 2008 Int J Obes (Lond) pmid:18719594
Lopaschuk GD AMP-activated protein kinase control of energy metabolism in the ischemic heart. 2008 Int J Obes (Lond) pmid:18719595
Lane MD et al. Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. 2008 Int J Obes (Lond) pmid:18719599
Wattanachaisaereekul S et al. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. 2008 Metab. Eng. pmid:18555717
Zammit VA and Arduini A The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. 2008 Cell Metab. pmid:18762014
Tsfadia O et al. Pheromone biosynthetic pathways: PBAN-regulated rate-limiting steps and differential expression of desaturase genes in moth species. 2008 Insect Biochem. Mol. Biol. pmid:18405833
Singh SP et al. Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. 2008 Biochemistry pmid:18311940
Ghadbane H et al. Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). 2007 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:17909282
Guay C et al. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. 2007 J. Biol. Chem. pmid:17928289
Thomson DM et al. LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17925454
Liu Y et al. Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. 2007 Assay Drug Dev Technol pmid:17477831
Noland RC et al. Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17638705
Gu L et al. GNAT-like strategy for polyketide chain initiation. 2007 Science pmid:17991863
Wolfgang MJ et al. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18032600
Ma SM et al. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. 2007 J. Am. Chem. Soc. pmid:17696354
Cahová M et al. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. 2007 Physiol Res pmid:16497094
Patil PB et al. Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. 2007 Arch. Physiol. Biochem. pmid:17522981