To understand associated biological information of Palmitoyl coenzyme a, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Palmitoyl coenzyme a is suspected in Parkinson Disease and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Palmitoyl coenzyme a
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Riboflavin Deficiency | D012257 | 10 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Mitochondrial Diseases | D028361 | 25 associated lipids |
| Togaviridae Infections | D014036 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Rodent Model are used in the study 'Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels.' (Worth AJ et al., 2014).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hara A et al. | Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. | 2017 | Biochem. Pharmacol. | pmid:28450226 |
| Cortassa S et al. | Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study. | 2017 | PLoS Comput. Biol. | pmid:28598967 |
| Ritchie MK et al. | Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE. | 2016 | J. Biol. Chem. | pmid:26663084 |
| Soupene E et al. | Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA. | 2016 | J. Lipid Res. | pmid:26621918 |
| Albesa-Jové D et al. | Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA. | 2016 | Nat Commun | pmid:26965057 |
| Seeßle J et al. | Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis. | 2015 | Biochim. Biophys. Acta | pmid:25603556 |
| Kaylor JJ et al. | Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium. | 2015 | PLoS ONE | pmid:25974161 |
| Ludzki A et al. | Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling. | 2015 | Diabetes | pmid:25845660 |
| Tuvdendorj D et al. | Triglycerides produced in the livers of fasting rabbits are predominantly stored as opposed to secreted into the plasma. | 2015 | Metab. Clin. Exp. | pmid:25682063 |
| Alefishat E et al. | Effects of NAD at purine receptors in isolated blood vessels. | 2015 | Purinergic Signal. | pmid:25315718 |