Acetyl-d-carnitine

Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2875 references associated with Acetyl-d-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Acetyl-d-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Alzheimer Disease D000544 76 associated lipids
Parkinson Disease D010300 53 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Cleft Lip D002971 8 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 7

All references with Acetyl-d-carnitine

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Authors Title Published Journal PubMed Link
Phillipson OT Management of the aging risk factor for Parkinson's disease. 2014 Neurobiol. Aging pmid:24246717
Uziel G et al. Carnitine stimulation of pyruvate dehydrogenase complex (PDHC) in isolated human skeletal muscle mitochondria. 1988 Muscle Nerve pmid:3405240
Elanchezhian R et al. Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation. 2009 Mol. Vis. pmid:19649174
Muralidharan AR et al. Deciphering the potential efficacy of acetyl-L-carnitine (ALCAR) in maintaining connexin-mediated lenticular homeostasis. 2012 Mol. Vis. pmid:22876134
Lau T et al. Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant. 2017 Mol. Psychiatry pmid:27240534
Chiechio S et al. L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. 2002 Mol. Pharmacol. pmid:11961116
Behrend AM et al. Substrate oxidation and cardiac performance during exercise in disorders of long chain fatty acid oxidation. 2012 Mol. Genet. Metab. pmid:22030098
Löster H et al. Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy. 1999 Mol. Cell. Biochem. pmid:10569188
Cui J et al. Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. 2003 Mol. Cell. Biochem. pmid:14674702
Hu C et al. Inhibition of OCTN2-mediated transport of carnitine by etoposide. 2012 Mol. Cancer Ther. pmid:22389472
Chiechio S et al. Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. 2006 Mol Pain pmid:16764720
Notartomaso S et al. Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain. 2017 Mol Pain pmid:28326943
Pekkinen J et al. Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. 2013 Mol Nutr Food Res pmid:23868375
Calabrese V et al. Redox homeostasis and cellular stress response in aging and neurodegeneration. 2010 Methods Mol. Biol. pmid:20013185
Cotter MA et al. Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes. 1995 Metab. Clin. Exp. pmid:7666797
Brass EP and Beyerinck RA Interactions of propionate and carnitine metabolism in isolated rat hepatocytes. 1987 Metab. Clin. Exp. pmid:3110541
Parr TB A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop. 2001 Med. Hypotheses pmid:11388776
Paradies G et al. Carnitine-acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine. 1995 Mech. Ageing Dev. pmid:8788238
Gómez LA et al. Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart. 2012 Feb-Mar Mech. Ageing Dev. pmid:22322067
Kerner J et al. Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart. 2015 Mech. Ageing Dev. pmid:25660059

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