Gago MF et al. |
SANDO: two novel mutations in POLG1 gene. |
2006 |
Neuromuscul. Disord. |
pmid:16919951
|
Kottlors M et al. |
Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. |
2001 |
Neuromuscul. Disord. |
pmid:11595519
|
Masi F et al. |
Effects of long-term acetyl-L-carnitine administration in rats--II: Protection against the disrupting effect of stress on the acquisition of appetitive behavior. |
2003 |
Neuropsychopharmacology |
pmid:12655313
|
Tolu P et al. |
Effects of long-term acetyl-L-carnitine administration in rats: I. increased dopamine output in mesocorticolimbic areas and protection toward acute stress exposure. |
2002 |
Neuropsychopharmacology |
pmid:12225698
|
Cuccurazzu B et al. |
Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the Proneurogenic and antidepressant effects of acetyl-L-carnitine. |
2013 |
Neuropsychopharmacology |
pmid:23670591
|
Binienda ZK et al. |
Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol. |
2010 |
Neurosci. Lett. |
pmid:20542088
|
Sarkar S et al. |
Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-L-carnitine. |
2015 |
Neurosci. Lett. |
pmid:26321151
|
Robinson BL et al. |
Opposing effects of ketamine and acetyl L-carnitine on the serotonergic system of zebrafish. |
2015 |
Neurosci. Lett. |
pmid:26365406
|
Flatters SJ et al. |
Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy. |
2006 |
Neurosci. Lett. |
pmid:16406309
|
Patel SP et al. |
Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery. |
2012 |
Neuroscience |
pmid:22445934
|
Nagesh Babu G et al. |
Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function. |
2011 |
Neurotox Res |
pmid:20217290
|
Robinson BL et al. |
Distinct effects of ketamine and acetyl L-carnitine on the dopamine system in zebrafish. |
2016 Mar-Apr |
Neurotoxicol Teratol |
pmid:26898327
|
Cuevas E et al. |
Acetyl L-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos. |
2013 Sep-Oct |
Neurotoxicol Teratol |
pmid:23896048
|
Katoh T et al. |
[Application of Metabolomics to Multiple Chemical Sensitivity Research]. |
2016 |
Nihon Eiseigaku Zasshi |
pmid:26832623
|
Suchy J et al. |
Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. |
2009 |
Nutr Res |
pmid:19185780
|
Kathirvel E et al. |
Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. |
2013 |
Nutr Res |
pmid:24176233
|
Burotto M and Fojo AT |
Acetyl-L-carnitine and prevention of chemotherapy-induced peripheral neuropathy: can anything work? |
2013 |
Oncologist |
pmid:24217999
|
Campone M et al. |
A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy. |
2013 |
Oncologist |
pmid:24105751
|
De Luca A et al. |
Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells. |
2015 |
Oncotarget |
pmid:26087310
|
Feher J et al. |
Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. |
2003 Sep-Oct |
Ophthalmologica |
pmid:12913326
|
Feher J et al. |
Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10. |
2005 May-Jun |
Ophthalmologica |
pmid:15947501
|
Fehér J et al. |
[Metabolic therapy for early treatment of age-related macular degeneration]. |
2007 |
Orv Hetil |
pmid:18039616
|
Xiao WH and Bennett GJ |
Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-L-carnitine. |
2008 |
Pain |
pmid:17659836
|
Kopsky DJ and Hesselink JM |
Nerve regeneration in neuropathic pain. |
2010 |
Pain Med |
pmid:21199307
|
Li X et al. |
An acetyl-L-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminum oxide nanoparticles. |
2016 |
Part Fibre Toxicol |
pmid:26772537
|
Tyni T et al. |
Analysis of mitochondrial fatty acid oxidation intermediates by tandem mass spectrometry from intact mitochondria prepared from homogenates of cultured fibroblasts, skeletal muscle cells, and fresh muscle. |
2002 |
Pediatr. Res. |
pmid:12084849
|
Van Hove JL et al. |
Intravenous L-carnitine and acetyl-L-carnitine in medium-chain acyl-coenzyme A dehydrogenase deficiency and isovaleric acidemia. |
1994 |
Pediatr. Res. |
pmid:8134205
|
Hack A et al. |
Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis. |
2006 |
Pediatr. Res. |
pmid:16690958
|
Okamura N et al. |
Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. |
2006 |
Pharm. Res. |
pmid:16826461
|
Zaitone SA et al. |
Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. |
2012 |
Pharmacol. Biochem. Behav. |
pmid:21958946
|
Virmani MA et al. |
Protective actions of L-carnitine and acetyl-L-carnitine on the neurotoxicity evoked by mitochondrial uncoupling or inhibitors. |
1995 |
Pharmacol. Res. |
pmid:8736490
|
Valoti M et al. |
Effects of carnitine and its derivatives on gastric acid secretion in rats. |
1996 Nov-Dec |
Pharmacol. Res. |
pmid:9076846
|
Arafa HM and Sayed-Ahmed MM |
Protective role of carnitine esters against alcohol-induced gastric lesions in rats. |
2003 |
Pharmacol. Res. |
pmid:12860448
|
Mansour HH |
Protective role of carnitine ester against radiation-induced oxidative stress in rats. |
2006 |
Pharmacol. Res. |
pmid:16757176
|
Marciani P et al. |
L-carnitine and carnitine ester transport in the rat small intestine. |
1991 |
Pharmacol. Res. |
pmid:2062791
|
Babicová A et al. |
In vivo study of radioprotective effect of NO-synthase inhibitors and acetyl-L-carnitine. |
2013 |
Physiol Res |
pmid:23869893
|
Pracharoenwattana I et al. |
Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. |
2005 |
Plant Cell |
pmid:15923350
|
Fiehn O et al. |
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. |
2010 |
PLoS ONE |
pmid:21170321
|
Diekman EF et al. |
Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency. |
2016 |
PLoS ONE |
pmid:26881790
|
Lindsay KL et al. |
Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy. |
2015 |
PLoS ONE |
pmid:26716698
|
Macconi D et al. |
Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II. |
2015 |
PLoS ONE |
pmid:25993470
|
Li S et al. |
Acetyl-L-carnitine in the treatment of peripheral neuropathic pain: a systematic review and meta-analysis of randomized controlled trials. |
2015 |
PLoS ONE |
pmid:25751285
|
Wang CH et al. |
Acetyl-l-carnitine and oxfenicine on cardiac pumping mechanics in streptozotocin-induced diabetes in male Wistar rats. |
2013 |
PLoS ONE |
pmid:23922880
|
Lodi A et al. |
Proton NMR-based metabolite analyses of archived serial paired serum and urine samples from myeloma patients at different stages of disease activity identifies acetylcarnitine as a novel marker of active disease. |
2013 |
PLoS ONE |
pmid:23431376
|
Zuena AR et al. |
Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine. |
2013 |
PLoS ONE |
pmid:23409035
|
Federighi G et al. |
Differentially expressed genes in Hirudo medicinalis ganglia after acetyl-L-carnitine treatment. |
2013 |
PLoS ONE |
pmid:23308261
|
Schaevitz LR et al. |
Acetyl-L-carnitine improves behavior and dendritic morphology in a mouse model of Rett syndrome. |
2012 |
PLoS ONE |
pmid:23227269
|
Karalija A et al. |
Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats. |
2012 |
PLoS ONE |
pmid:22815926
|
Abdul Muneer PM et al. |
Methamphetamine inhibits the glucose uptake by human neurons and astrocytes: stabilization by acetyl-L-carnitine. |
2011 |
PLoS ONE |
pmid:21556365
|
Masterson C and Wood C |
Pea chloroplast carnitine acetyltransferase. |
2000 |
Proc. Biol. Sci. |
pmid:10670945
|
Hagen TM et al. |
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9689120
|
Russo SJ and Charney DS |
Next generation antidepressants. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23471996
|
Nasca C et al. |
L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23382250
|
Wu R et al. |
Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22328148
|
Hagen TM et al. |
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11854487
|
Liu J et al. |
Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11854488
|
Liu J et al. |
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11854529
|
Abdul Muneer PM et al. |
Inhibitory effects of alcohol on glucose transport across the blood-brain barrier leads to neurodegeneration: preventive role of acetyl-L: -carnitine. |
2011 |
Psychopharmacology (Berl.) |
pmid:21079922
|
Vermeulen RC and Scholte HR |
Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. |
2004 Mar-Apr |
Psychosom Med |
pmid:15039515
|
Lal A et al. |
Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts. |
2008 |
Redox Rep. |
pmid:18284845
|
Kobayashi D et al. |
Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa. |
2007 |
Reproduction |
pmid:17965255
|
Kobayashi D et al. |
Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells. |
2005 |
Reproduction |
pmid:16322553
|
Calvani M et al. |
[L-acetylcarnitine treatment on fragile X patients hyperactive behaviour]. |
2001 |
Rev Neurol |
pmid:12447823
|
Huber K et al. |
Metabotypes with properly functioning mitochondria and anti-inflammation predict extended productive life span in dairy cows. |
2016 |
Sci Rep |
pmid:27089826
|
Rosenthal RE et al. |
Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine. |
1992 |
Stroke |
pmid:1519288
|
Morand R et al. |
Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. |
2012 |
Ther Drug Monit |
pmid:22743351
|
Hori T et al. |
Carnitine palmitoyltransferase 2 deficiency: the time-course of blood and urinary acylcarnitine levels during initial L-carnitine supplementation. |
2010 |
Tohoku J. Exp. Med. |
pmid:20543534
|
Itoh T et al. |
Effect of carnitine administration on glycine metabolism in patients with isovaleric acidemia: significance of acetylcarnitine determination to estimate the proper carnitine dose. |
1996 |
Tohoku J. Exp. Med. |
pmid:8875766
|
Ponte F et al. |
Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes. |
2011 |
Toxicology |
pmid:21807063
|
Laird MD et al. |
Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. |
2013 |
Transl Stroke Res |
pmid:24323418
|
Li S and Laher I |
Exercise Pills: At the Starting Line. |
2015 |
Trends Pharmacol. Sci. |
pmid:26439443
|
Curran MW et al. |
Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial. |
2016 |
Trials |
pmid:27079660
|
Kotil K et al. |
Neuroprotective effects of acetyl-L-carnithine in experimental chronic compression neuropathy. A prospective, randomized and placebo-control trials. |
2007 |
Turk Neurosurg |
pmid:17935020
|
Cavallini G et al. |
Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. |
2005 |
Urology |
pmid:16286128
|
Mingorance C et al. |
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders. |
2011 |
Vasc Health Risk Manag |
pmid:21490942
|
Capecchi PL et al. |
Carnitines increase plasma levels of adenosine and ATP in humans. |
1997 |
Vasc Med |
pmid:9546959
|
Wu SN et al. |
[Analysis of propionylcarnitine in blood and methylmalonic acid in urine of 162 patients with methylmalonic acidemia]. |
2013 |
Zhonghua Yi Xue Za Zhi |
pmid:23663331
|