Acetyl-d-carnitine

Acetyl-d-carnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2875 references associated with Acetyl-d-carnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Acetyl-d-carnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Acetyl-d-carnitine

MeSH term MeSH ID Detail
Proteostasis Deficiencies D057165 5 associated lipids
Parkinson Disease D010300 53 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Cleft Lip D002971 8 associated lipids
Body Weight D001835 333 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Alzheimer Disease D000544 76 associated lipids
Total 7

All references with Acetyl-d-carnitine

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Authors Title Published Journal PubMed Link
Patel SP et al. Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery. 2012 Neuroscience pmid:22445934
Ren J et al. Dynamic monitoring of carnitine and acetylcarnitine in the trimethylamine signal after exercise in human skeletal muscle by 7T 1H-MRS. 2013 Magn Reson Med pmid:22473634
Wadman RI et al. Drug treatment for spinal muscular atrophy types II and III. 2012 Cochrane Database Syst Rev pmid:22513940
pmid:22533417
pmid:22549035
Muoio DM et al. Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. 2012 Cell Metab. pmid:22560225
Sharma S et al. Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. 2012 Free Radic. Biol. Med. pmid:22583703
pmid:22592719
pmid:2262440
Smeland OB et al. Dietary supplementation with acetyl-l-carnitine in seizure treatment of pentylenetetrazole kindled mice. 2012 Neurochem. Int. pmid:22709675
Morand R et al. Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. 2012 Ther Drug Monit pmid:22743351
pmid:22753396
Karalija A et al. Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats. 2012 PLoS ONE pmid:22815926
Hu S et al. Use of hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat. 2012 Magn Reson Imaging pmid:22819176
Ang JE et al. Identification of human plasma metabolites exhibiting time-of-day variation using an untargeted liquid chromatography-mass spectrometry metabolomic approach. 2012 Chronobiol. Int. pmid:22823870
Muralidharan AR et al. Deciphering the potential efficacy of acetyl-L-carnitine (ALCAR) in maintaining connexin-mediated lenticular homeostasis. 2012 Mol. Vis. pmid:22876134
pmid:2289524
pmid:22947198
Mallinson JE et al. Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents. 2012 J. Physiol. (Lond.) pmid:23045346
pmid:2306109
Kanazirska MV et al. Beneficial effects of lysosome-modulating and other pharmacological and nanocarrier agents on amyloid-beta-treated cells. 2012 Curr Pharm Biotechnol pmid:23072393
pmid:23081917
pmid:231113
pmid:23214468
Schaevitz LR et al. Acetyl-L-carnitine improves behavior and dendritic morphology in a mouse model of Rett syndrome. 2012 PLoS ONE pmid:23227269
pmid:2323071
Sahlin K Muscle carnitine metabolism during incremental dynamic exercise in humans. 1990 Acta Physiol. Scand. pmid:2327259
pmid:23278446
Siliprandi N et al. Metabolic changes induced by maximal exercise in human subjects following L-carnitine administration. 1990 Biochim. Biophys. Acta pmid:2328258
pmid:23296212
Federighi G et al. Differentially expressed genes in Hirudo medicinalis ganglia after acetyl-L-carnitine treatment. 2013 PLoS ONE pmid:23308261
Nasca C et al. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:23382250
pmid:23386399
pmid:23389620
pmid:2339783
Zuena AR et al. Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine. 2013 PLoS ONE pmid:23409035
pmid:23411015
Mazzocchio R et al. Enhancement of recurrent inhibition by intravenous administration of L-acetylcarnitine in spastic patients. 1990 J. Neurol. Neurosurg. Psychiatry pmid:2341845
pmid:23421600
pmid:23428336
Lodi A et al. Proton NMR-based metabolite analyses of archived serial paired serum and urine samples from myeloma patients at different stages of disease activity identifies acetylcarnitine as a novel marker of active disease. 2013 PLoS ONE pmid:23431376
pmid:2344045
Russo SJ and Charney DS Next generation antidepressants. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:23471996
Hanada H et al. Acetyl-L-carnitine suppresses thyroid hormone-induced and spontaneous anuran tadpole tail shortening. 2013 Hereditas pmid:23489246
pmid:23545238
Ryckman KK et al. The influence of maternal disease on metabolites measured as part of newborn screening. 2013 J. Matern. Fetal. Neonatal. Med. pmid:23550828
pmid:23625722
Schloss JM et al. Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): a systematic review. 2013 Clin Nutr pmid:23647723
Wu SN et al. [Analysis of propionylcarnitine in blood and methylmalonic acid in urine of 162 patients with methylmalonic acidemia]. 2013 Zhonghua Yi Xue Za Zhi pmid:23663331
Cuccurazzu B et al. Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the Proneurogenic and antidepressant effects of acetyl-L-carnitine. 2013 Neuropsychopharmacology pmid:23670591

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